Inhibition of SF3B1 by molecules targeting the spliceosome results in massive aberrant exon skipping

por Wu, Gang, Fan, Liying, Edmonson, Michael N., Shaw, Timothy, Boggs, Kristy, Easton, John, Rusch, Michael C., Webb, Thomas R., Zhang, Jinghui, Potter, Philip M.
Publicado 2018

The landscape of coding RNA editing events in pediatric cancer

por Wen, Ji, Rusch, Michael, Brady, Samuel W., Shao, Ying, Edmonson, Michael N., Shaw, Timothy I., Powers, Brent B., Tian, Liqing, Easton, John, Mullighan, Charles G., Gruber, Tanja, Ellison, David, Zhang, Jinghui
Publicado 2021

The neoepitope landscape in pediatric cancers

por Chang, Ti-Cheng, Carter, Robert A., Li, Yongjin, Li, Yuxin, Wang, Hong, Edmonson, Michael N., Chen, Xiang, Arnold, Paula, Geiger, Terrence L., Wu, Gang, Peng, Junmin, Dyer, Michael, Downing, James R., Green, Douglas R., Thomas, Paul G., Zhang, Jinghui
Publicado 2017

Analysis of error profiles in deep next-generation sequencing data

por Ma, Xiaotu, Shao, Ying, Tian, Liqing, Flasch, Diane A., Mulder, Heather L., Edmonson, Michael N., Liu, Yu, Chen, Xiang, Newman, Scott, Nakitandwe, Joy, Li, Yongjin, Li, Benshang, Shen, Shuhong, Wang, Zhaoming, Shurtleff, Sheila, Robison, Leslie L., Levy, Shawn, Easton, John, Zhang, Jinghui
Publicado 2019

CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data

por Tian, Liqing, Li, Yongjin, Edmonson, Michael N., Zhou, Xin, Newman, Scott, McLeod, Clay, Thrasher, Andrew, Liu, Yu, Tang, Bo, Rusch, Michael C., Easton, John, Ma, Jing, Davis, Eric, Trull, Austyn, Michael, J. Robert, Szlachta, Karol, Mullighan, Charles, Baker, Suzanne J., Downing, James R., Ellison, David W., Zhang, Jinghui
Publicado 2020

Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X

por Liu, Yu, Li, Chunliang, Shen, Shuhong, Chen, Xiaolong, Szlachta, Karol, Edmonson, Michael N., Shao, Ying, Ma, Xiaotu, Hyle, Judith, Wright, Shaela, Ju, Bensheng, Rusch, Michael C., Liu, Yanling, Li, Benshang, Macias, Michael, Tian, Liqing, Easton, John, Qian, Maoxiang, Yang, Jun J., Hu, Shaoyan, Look, A. Thomas, Zhang, Jinghui
Publicado 2020

Pediatric Cancer Variant Pathogenicity Information Exchange (PeCanPIE): a cloud-based platform for curating and classifying germline variants

por Edmonson, Michael N., Patel, Aman N., Hedges, Dale J., Wang, Zhaoming, Rampersaud, Evadnie, Kesserwan, Chimene A., Zhou, Xin, Liu, Yanling, Newman, Scott, Rusch, Michael C., McLeod, Clay L., Wilkinson, Mark R., Rice, Stephen V., Soussi, Thierry, Taylor, J. Paul, Benatar, Michael, Becksfort, Jared B., Nichols, Kim E., Robison, Leslie L., Downing, James R., Zhang, Jinghui
Publicado 2019

Defining the condensate landscape of fusion oncoproteins

por Tripathi, Swarnendu, Shirnekhi, Hazheen K., Gorman, Scott D., Chandra, Bappaditya, Baggett, David W., Park, Cheon-Gil, Somjee, Ramiz, Lang, Benjamin, Hosseini, Seyed Mohammad Hadi, Pioso, Brittany J., Li, Yongsheng, Iacobucci, Ilaria, Gao, Qingsong, Edmonson, Michael N., Rice, Stephen V., Zhou, Xin, Bollinger, John, Mitrea, Diana M., White, Michael R., McGrail, Daniel J., Jarosz, Daniel F., Yi, S. Stephen, Babu, M. Madan, Mullighan, Charles G., Zhang, Jinghui, Sahni, Nidhi, Kriwacki, Richard W.
Publicado 2023

Enrichment of heterozygous germline RECQL4 loss-of-function variants in pediatric osteosarcoma

por Maciaszek, Jamie L., Oak, Ninad, Chen, Wenan, Hamilton, Kayla V., McGee, Rose B., Nuccio, Regina, Mostafavi, Roya, Hines-Dowell, Stacy, Harrison, Lynn, Taylor, Leslie, Gerhardt, Elsie L., Ouma, Annastasia, Edmonson, Michael N., Patel, Aman, Nakitandwe, Joy, Pappo, Alberto S., Azzato, Elizabeth M., Shurtleff, Sheila A., Ellison, David W., Downing, James R., Hudson, Melissa M., Robison, Leslie L., Santana, Victor, Newman, Scott, Zhang, Jinghui, Wang, Zhaoming, Wu, Gang, Nichols, Kim E., Kesserwan, Chimene A.
Publicado 2019

Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome

por Rusch, Michael, Nakitandwe, Joy, Shurtleff, Sheila, Newman, Scott, Zhang, Zhaojie, Edmonson, Michael N., Parker, Matthew, Jiao, Yuannian, Ma, Xiaotu, Liu, Yanling, Gu, Jiali, Walsh, Michael F., Becksfort, Jared, Thrasher, Andrew, Li, Yongjin, McMurry, James, Hedlund, Erin, Patel, Aman, Easton, John, Yergeau, Donald, Vadodaria, Bhavin, Tatevossian, Ruth G., Raimondi, Susana, Hedges, Dale, Chen, Xiang, Hagiwara, Kohei, McGee, Rose, Robinson, Giles W., Klco, Jeffery M., Gruber, Tanja A., Ellison, David W., Downing, James R, Zhang, Jinghui
Publicado 2018

Pan-cancer genome and transcriptome analyses of 1,699 pediatric leukemias and solid tumors

por Ma, Xiaotu, Liu, Yu, Liu, Yanling, Alexandrov, Ludmil B, Edmonson, Michael N., Gawad, Charles, Zhou, Xin, Li, Yongjin, Rusch, Michael C., Easton, John, Huether, Robert, Gonzalez-Pena, Veronica, Wilkinson, Mark R., Hermida, Leandro C., Davis, Sean, Sioson, Edgar, Pounds, Stanley, Cao, Xueyuan, Ries, Rhonda E., Wang, Zhaoming, Chen, Xiang, Dong, Li, Diskin, Sharon J., Smith, Malcolm A., Guidry Auvil, Jaime M., Meltzer, Paul S., Lau, Ching C., Perlman, Elizabeth J., Maris, John M., Meshinchi, Soheil, Hunger, Stephen P., Gerhard, Daniela S., Zhang, Jinghui
Publicado 2018

Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing

por Newman, Scott, Nakitandwe, Joy, Kesserwan, Chimene A., Azzato, Elizabeth M., Wheeler, David A., Rusch, Michael, Shurtleff, Sheila, Hedges, Dale J., Hamilton, Kayla V., Foy, Scott G., Edmonson, Michael N., Thrasher, Andrew, Bahrami, Armita, Orr, Brent A., Klco, Jeffery M., Gu, Jiali, Harrison, Lynn W., Wang, Lu, Clay, Michael R., Ouma, Annastasia, Silkov, Antonina, Liu, Yanling, Zhang, Zhaojie, Liu, Yu, Brady, Samuel W., Zhou, Xin, Chang, Ti-Cheng, Pande, Manjusha, Davis, Eric, Becksfort, Jared, Patel, Aman, Wilkinson, Mark R., Rahbarinia, Delaram, Kubal, Manish, Maciaszek, Jamie L., Pastor, Victor, Knight, Jay, Gout, Alexander M., Wang, Jian, Gu, Zhaohui, Mullighan, Charles G., McGee, Rose B., Quinn, Emily A., Nuccio, Regina, Mostafavi, Roya, Gerhardt, Elsie L., Taylor, Leslie M., Valdez, Jessica M., Hines-Dowell, Stacy J., Pappo, Alberto S., Robinson, Giles, Johnson, Liza-Marie, Pui, Ching-Hon, Ellison, David W., Downing, James R., Zhang, Jinghui, Nichols, Kim E.
Publicado 2021