Messenger ribonucleic acid vaccines against infectious diseases: current concepts and future prospects

por Edwards, Darin K, Carfi, Andrea
Publicado 2022

Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response

por Edwards, Darin K., Jasny, Edith, Yoon, Heesik, Horscroft, Nigel, Schanen, Brian, Geter, Tanya, Fotin-Mleczek, Mariola, Petsch, Benjamin, Wittman, Vaughan
Publicado 2017

Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants

por Choi, Angela, Koch, Matthew, Wu, Kai, Dixon, Groves, Oestreicher, Judy, Legault, Holly, Stewart-Jones, Guillaume B. E., Colpitts, Tonya, Pajon, Rolando, Bennett, Hamilton, Carfi, Andrea, Edwards, Darin K.
Publicado 2021

Safety and Immunogenicity of a 100 μg mRNA-1273 Vaccine Booster for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)

por Chalkias, Spyros, Schwartz, Howard, Nestorova, Biliana, Feng, Jing, Chang, Ying, Zhou, Honghong, Dutko, Frank J., Edwards, Darin K., Montefiori, David, Pajon, Rolando, Leav, Brett, Miller, Jacqueline M., Das, Rituparna
Publicado 2022

Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2

por Mackin, Samantha R., Desai, Pritesh, Whitener, Bradley M., Karl, Courtney E., Liu, Meizi, Baric, Ralph S., Edwards, Darin K., Chicz, Taras M., McNamara, Ryan P., Alter, Galit, Diamond, Michael S.
Publicado 2022

Immune response to SARS-CoV-2 after a booster of mRNA-1273: an open-label phase 2 trial

por Chu, Laurence, Vrbicky, Keith, Montefiori, David, Huang, Wenmei, Nestorova, Biliana, Chang, Ying, Carfi, Andrea, Edwards, Darin K., Oestreicher, Judy, Legault, Holly, Dutko, Frank J., Girard, Bethany, Pajon, Rolando, Miller, Jacqueline M., Das, Rituparna, Leav, Brett, McPhee, Roderick
Publicado 2022

Serum Neutralizing Activity Elicited by mRNA-1273 Vaccine

por Wu, Kai, Werner, Anne P., Koch, Matthew, Choi, Angela, Narayanan, Elisabeth, Stewart-Jones, Guillaume B.E., Colpitts, Tonya, Bennett, Hamilton, Boyoglu-Barnum, Seyhan, Shi, Wei, Moliva, Juan I., Sullivan, Nancy J., Graham, Barney S., Carfi, Andrea, Corbett, Kizzmekia S., Seder, Robert A., Edwards, Darin K.
Publicado 2021

Safety, immunogenicity and antibody persistence of a bivalent Beta-containing booster vaccine against COVID-19: a phase 2/3 trial

por Chalkias, Spyros, Eder, Frank, Essink, Brandon, Khetan, Shishir, Nestorova, Biliana, Feng, Jing, Chen, Xing, Chang, Ying, Zhou, Honghong, Montefiori, David, Edwards, Darin K., Girard, Bethany, Pajon, Rolando, Dutko, Frank J., Leav, Brett, Walsh, Stephen R., Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Publicado 2022

Three-month antibody persistence of a bivalent Omicron-containing booster vaccine against COVID-19

por Chalkias, Spyros, Harper, Charles, Vrbicky, Keith, Walsh, Stephen R., Essink, Brandon, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Ying Chang, Sutherland, Andrea, Montefiori, David C., Girard, Bethany, Edwards, Darin K., Jing Feng, Zhou, Honghong, Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Publicado 2023

A Bivalent Omicron-Containing Booster Vaccine against Covid-19

por Chalkias, Spyros, Harper, Charles, Vrbicky, Keith, Walsh, Stephen R., Essink, Brandon, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Chang, Ying, Sutherland, Andrea, Montefiori, David C., Girard, Bethany, Edwards, Darin K., Feng, Jing, Zhou, Honghong, Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Publicado 2022

Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates

por Schramm, Chaim A., Moon, Damee, Peyton, Lowrey, Lima, Noemia S., Wake, Christian, Boswell, Kristin L., Henry, Amy R., Laboune, Farida, Ambrozak, David, Darko, Samuel W., Teng, I-Ting, Foulds, Kathryn E., Carfi, Andrea, Edwards, Darin K., Kwong, Peter D., Koup, Richard A., Seder, Robert A., Douek, Daniel C.
Publicado 2023

mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2

por Darling, Tamarand L., Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Bricker, Traci L., Liang, Chieh-Yu, Joshi, Astha, Bamunuarachchi, Gayan, Seehra, Kuljeet, Schmitz, Aaron J., Halfmann, Peter J., Kawaoka, Yoshihiro, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S., Boon, Adrianus C.M.
Publicado 2022

Safety and immunogenicity of SARS-CoV-2 variant mRNA vaccine boosters in healthy adults: an interim analysis

por Choi, Angela, Koch, Matthew, Wu, Kai, Chu, Laurence, Ma, LingZhi, Hill, Anna, Nunna, Naveen, Huang, Wenmei, Oestreicher, Judy, Colpitts, Tonya, Bennett, Hamilton, Legault, Holly, Paila, Yamuna, Nestorova, Biliana, Ding, Baoyu, Montefiori, David, Pajon, Rolando, Miller, Jacqueline M., Leav, Brett, Carfi, Andrea, McPhee, Roderick, Edwards, Darin K.
Publicado 2021

Original SARS-CoV-2 monovalent and Omicron BA.4/BA.5 bivalent COVID-19 mRNA vaccines: phase 2/3 trial interim results

por Chalkias, Spyros, Whatley, Jordan L., Eder, Frank, Essink, Brandon, Khetan, Shishir, Bradley, Paul, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Zhao, Xiaoping, Sutherland, Andrea, Shen, Xiaoying, Girard, Bethany, Edwards, Darin K., Feng, Jing, Zhou, Honghong, Walsh, Stephen, Montefiori, David C., Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Publicado 2023

Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection

por Baldeon Vaca, Gabriela, Meyer, Michelle, Cadete, Ana, Hsiao, Chiaowen Joyce, Golding, Anne, Jeon, Albert, Jacquinet, Eric, Azcue, Emily, Guan, Chenxia Monica, Sanchez-Felix, Xavier, Pietzsch, Colette A., Mire, Chad E., Hyde, Matthew A., Comeaux, Margaret E., Williams, Julie M., Sung, Jean C., Carfi, Andrea, Edwards, Darin K., Bukreyev, Alexander, Bahl, Kapil
Publicado 2023

Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice

por Ying, Baoling, Scheaffer, Suzanne M., Whitener, Bradley, Liang, Chieh-Yu, Dmytrenko, Oleksandr, Mackin, Samantha, Wu, Kai, Lee, Diana, Avena, Laura E., Chong, Zhenlu, Case, James Brett, Ma, LingZhi, Kim, Thu, Sein, Caralyn, Woods, Angela, Berrueta, Daniela Montes, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2022

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

por Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda, Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2021

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

por Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2021

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

por Wu, Kai, Choi, Angela, Koch, Matthew, Elbashir, Sayda, Ma, LingZhi, Lee, Diana, Woods, Angela, Henry, Carole, Palandjian, Charis, Hill, Anna, Jani, Hardik, Quinones, Julian, Nunna, Naveen, O'Connell, Sarah, McDermott, Adrian B., Falcone, Samantha, Narayanan, Elisabeth, Colpitts, Tonya, Bennett, Hamilton, Corbett, Kizzmekia S., Seder, Robert, Graham, Barney S., Stewart-Jones, Guillaume B.E., Carfi, Andrea, Edwards, Darin K.
Publicado 2021

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant

por Scheaffer, Suzanne M., Lee, Diana, Whitener, Bradley, Ying, Baoling, Wu, Kai, Jani, Hardik, Martin, Philippa, Amato, Nicholas J., Avena, Laura E., Berrueta, Daniela Montes, Schmidt, Stephen D., O’Dell, Sijy, Nasir, Arshan, Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Koup, Richard A., Doria-Rose, Nicole A., Carfi, Andrea, Elbashir, Sayda M., Thackray, Larissa B., Edwards, Darin K., Diamond, Michael S.
Publicado 2022