Dynamic range of GSK3α not GSK3β is essential for bidirectional synaptic plasticity at hippocampal CA3-CA1 synapses

por Shahab, Lion, Plattner, Florian, Irvine, Elaine E, Cummings, Damian M, Edwards, Frances A
Publicado 2014

Differential development of neuronal physiological responsiveness in two human neural stem cell lines

por Donato, Roberta, Miljan, Erik A, Hines, Susan J, Aouabdi, Sihem, Pollock, Kenneth, Patel, Sara, Edwards, Frances A, Sinden, John D
Publicado 2007

Large and Small Dendritic Spines Serve Different Interacting Functions in Hippocampal Synaptic Plasticity and Homeostasis

por Paulin, Joshua J. W., Haslehurst, Peter, Fellows, Alexander D., Liu, Wenfei, Jackson, Joshua D., Joel, Zelah, Cummings, Damian M., Edwards, Frances A.
Publicado 2016

Following spatial Aβ aggregation dynamics in evolving Alzheimer’s disease pathology by imaging stable isotope labeling kinetics

por Michno, Wojciech, Stringer, Katie M., Enzlein, Thomas, Passarelli, Melissa K., Escrig, Stephane, Vitanova, Karina, Wood, Jack, Blennow, Kaj, Zetterberg, Henrik, Meibom, Anders, Hopf, Carsten, Edwards, Frances A., Hanrieder, Jörg
Publicado 2021

Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

por Liu, Wenfei, Taso, Orjona, Wang, Rui, Bayram, Sevinc, Graham, Andrew C, Garcia-Reitboeck, Pablo, Mallach, Anna, Andrews, William D, Piers, Thomas M, Botia, Juan A, Pocock, Jennifer M, Cummings, Damian M, Hardy, John, Edwards, Frances A, Salih, Dervis A
Publicado 2020

First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression

por Cummings, Damian M., Liu, Wenfei, Portelius, Erik, Bayram, Sevinç, Yasvoina, Marina, Ho, Sui-Hin, Smits, Hélène, Ali, Shabinah S., Steinberg, Rivka, Pegasiou, Chrysia-Maria, James, Owain T., Matarin, Mar, Richardson, Jill C., Zetterberg, Henrik, Blennow, Kaj, Hardy, John A., Salih, Dervis A., Edwards, Frances A.
Publicado 2015

Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APP(Swe)/PSEN1(M146V) transgenic mice

por Medawar, Evelyn, Benway, Tiffanie A., Liu, Wenfei, Hanan, Taylor A., Haslehurst, Peter, James, Owain T., Yap, Kenrick, Muessig, Laurenz, Moroni, Fabia, Nahaboo Solim, Muzammil A., Baidildinova, Gaukhar, Wang, Rui, Richardson, Jill C., Cacucci, Francesca, Salih, Dervis A., Cummings, Damian M., Edwards, Frances A.
Publicado 2018

Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia

por Benitez, Diana P., Jiang, Shenyi, Wood, Jack, Wang, Rui, Hall, Chloe M., Peerboom, Carlijn, Wong, Natalie, Stringer, Katie M., Vitanova, Karina S., Smith, Victoria C., Joshi, Dhaval, Saito, Takashi, Saido, Takaomi C., Hardy, John, Hanrieder, Jörg, De Strooper, Bart, Salih, Dervis A., Tripathi, Takshashila, Edwards, Frances A., Cummings, Damian M.
Publicado 2021

Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study

por Chaney, Aisling M, Lopez-Picon, Francisco R, Serrière, Sophie, Wang, Rui, Bochicchio, Daniela, Webb, Samuel D, Vandesquille, Matthias, Harte, Michael K, Georgiadou, Christina, Lawrence, Catherine, Busson, Julie, Vercouillie, Johnny, Tauber, Clovis, Buron, Frédéric, Routier, Sylvain, Reekie, Tristan, Snellman, Anniina, Kassiou, Michael, Rokka, Johanna, Davies, Karen E, Rinne, Juha O, Salih, Dervis A, Edwards, Frances A, Orton, Llwyd D, Williams, Stephen R, Chalon, Sylvie, Boutin, Hervé
Publicado 2021