Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300: response to correspondence by Borzì et al.

por Sacitharan, Pradeep K., Gharios, George Bou, Edwards, James R.
Publicado 2019

Modeling the Human Bone–Tumor Niche: Reducing and Replacing the Need for Animal Data

por Rao, Srinivasa R, Edwards, Claire M, Edwards, James R
Publicado 2020

SIRT1 directly activates autophagy in human chondrocytes

por Sacitharan, Pradeep K., Bou-Gharios, George, Edwards, James R.
Publicado 2020

Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication

por Jun, Indong, Han, Hyung-Seop, Edwards, James R., Jeon, Hojeong
Publicado 2018

Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300

por Sacitharan, Pradeep K., Lwin, Seint, Gharios, George Bou, Edwards, James R.
Publicado 2018

Adiponectin signalling in bone homeostasis, with age and in disease

por Lewis, Jonathan W., Edwards, James R., Naylor, Amy J., McGettrick, Helen M.
Publicado 2021

Minimally Invasive Mitral Valve Procedures: The Current State

por Ritwick, Bhuyan, Chaudhuri, Krishanu, Crouch, Gareth, Edwards, James R. M., Worthington, Michael, Stuklis, Robert G.
Publicado 2013

An Osteoblast-Derived Proteinase Controls Tumor Cell Survival via TGF-beta Activation in the Bone Microenvironment

por Thiolloy, Sophie, Edwards, James R., Fingleton, Barbara, Rifkin, Daniel B., Matrisian, Lynn M., Lynch, Conor C.
Publicado 2012

Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells

por Zhuang, Junling, Zhang, Jianghong, Lwin, Seint T., Edwards, James R., Edwards, Claire M., Mundy, Gregory R., Yang, Xiangli
Publicado 2012

Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction

por Danilin, Sabrina, Merkel, Alyssa R., Johnson, Joshua R., Johnson, Rachelle W., Edwards, James R., Sterling, Julie A.
Publicado 2012

Ageing in the musculoskeletal system: Cellular function and dysfunction throughout life

por Roberts, Sally, Colombier, Pauline, Sowman, Aneka, Mennan, Claire, Rölfing, Jan H D, Guicheux, Jérôme, Edwards, James R
Publicado 2016

The polyphenol resveratrol promotes skeletal growth in mice through a sirtuin 1‐bone morphogenic protein 2 longevity axis

por Zhao, Ming, Ko, Seon‐Yle, Garrett, I Ross, Mundy, Gregory R, Gutierrez, Gloria E, Edwards, James R
Publicado 2018

Activation of NF-kappa B Signaling Promotes Growth of Prostate Cancer Cells in Bone

por Jin, Renjie, Sterling, Julie A., Edwards, James R., DeGraff, David J., Lee, Changki, Park, Serk In, Matusik, Robert J.
Publicado 2013

Hypoxia‐inducible factor 1‐alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl‐4‐hydroxylase 2

por Hulley, Philippa A, Bishop, Tammie, Vernet, Aude, Schneider, Jurgen E, Edwards, James R, Athanasou, Nick A, Knowles, Helen J
Publicado 2017

Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp)

por Rao, Srinivasa R., Olechnowicz, Sam W. Z., Krätschmer, Patrick, Jepson, James E. C., Edwards, Claire M., Edwards, James R.
Publicado 2019

Transcriptional Regulation of BMP2 Expression by the PTH-CREB Signaling Pathway in Osteoblasts

por Zhang, Rongrong, Edwards, James R., Ko, Seon-Yle, Dong, Shanshan, Liu, Hongbin, Oyajobi, Babatunde O., Papasian, Christopher, Deng, Hong-Wen, Zhao, Ming
Publicado 2011

The antidiabetic drug metformin acts on the bone microenvironment to promote myeloma cell adhesion to preosteoblasts and increase myeloma tumour burden in vivo

por Gámez, Beatriz, Morris, Emma V., Olechnowicz, Sam W.Z., Webb, Siobhan, Edwards, James R., Sowman, Aneka, Turner, Christina J., Edwards, Claire M.
Publicado 2021

Biodegradable Magnesium Alloys Promote Angio‐Osteogenesis to Enhance Bone Repair

por Han, Hyung‐Seop, Jun, Indong, Seok, Hyun‐Kwang, Lee, Kang‐Sik, Lee, Kyungwoo, Witte, Frank, Mantovani, Diego, Kim, Yu‐Chan, Glyn‐Jones, Sion, Edwards, James R.
Publicado 2020

Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

por Whitburn, Jessica, Rao, Srinivasa R., Morris, Emma V., Tabata, Sho, Hirayama, Akiyoshi, Soga, Tomoyoshi, Edwards, James R., Kaya, Zeynep, Palmer, Charlotte, Hamdy, Freddie C., Edwards, Claire M.
Publicado 2022

Transgenic zebrafish model for quantification and visualization of tissue toxicity caused by alloying elements in newly developed biodegradable metal

por Han, Hyung-Seop, Jang, Gun Hyuk, Jun, Indong, Seo, Hyunseon, Park, Jimin, Glyn-Jones, Sion, Seok, Hyun-Kwang, Lee, Kwan Hyi, Mantovani, Diego, Kim, Yu-Chan, Edwards, James R.
Publicado 2018