Modulation of the Dipole Potential of Model Lipid Membranes with Phytochemicals: Molecular Mechanisms, Structure–Activity Relationships, and Implications in Reconstituted Ion Chann...

por Efimova, Svetlana S., Ostroumova, Olga S.
Publicado 2023

Is the Membrane Lipid Matrix a Key Target for Action of Pharmacologically Active Plant Saponins?

por Efimova, Svetlana S., Ostroumova, Olga S.
Publicado 2021

Triggering the Amphotericin B Pore-Forming Activity by Phytochemicals

por Efimova, Svetlana S., Malykhina, Anna I., Ostroumova, Olga S.
Publicado 2023

Probing Amphotericin B Single Channel Activity by Membrane Dipole Modifiers

por Ostroumova, Olga S., Efimova, Svetlana S., Schagina, Ludmila V.
Publicado 2012

Alkaloids Modulate the Functioning of Ion Channels Produced by Antimicrobial Agents via an Influence on the Lipid Host

por Efimova, Svetlana S., Zakharova, Anastasiia A., Ostroumova, Olga S.
Publicado 2020

Phosphodiesterase Type 5 Inhibitors Greatly Affect Physicochemical Properties of Model Lipid Membranes

por Zakharova, Anastasiia A., Efimova, Svetlana S., Ostroumova, Olga S.
Publicado 2021

Lipid Microenvironment Modulates the Pore-Forming Ability of Polymyxin B

por Zakharova, Anastasiia A., Efimova, Svetlana S., Ostroumova, Olga S.
Publicado 2022

The Degree of Hydroxylation of Phenolic Rings Determines the Ability of Flavonoids and Stilbenes to Inhibit Calcium-Mediated Membrane Fusion

por Zlodeeva, Polina D., Shekunov, Egor V., Ostroumova, Olga S., Efimova, Svetlana S.
Publicado 2023

The Interaction of Dipole Modifiers with Polyene-Sterol Complexes

por Ostroumova, Olga S., Efimova, Svetlana S., Chulkov, Evgeny G., Schagina, Ludmila V.
Publicado 2012

Fengycin induces ion channels in lipid bilayers mimicking target fungal cell membranes

por Zakharova, Anastasiia A., Efimova, Svetlana S., Malev, Valery V., Ostroumova, Olga S.
Publicado 2019

Discovery of the Potentiator of the Pore-Forming Ability of Lantibiotic Nisin: Perspectives for Anticancer Therapy

por Chernyshova, Dayana N., Tyulin, Alexander A., Ostroumova, Olga S., Efimova, Svetlana S.
Publicado 2022

3-Amino-Substituted Analogues of Fusidic Acid as Membrane-Active Antibacterial Compounds

por Salimova, Elena V., Mozgovoj, Oleg S., Efimova, Svetlana S., Ostroumova, Olga S., Parfenova, Lyudmila V.
Publicado 2023

A new look at Hsp70 activity in phosphatidylserine-enriched membranes: chaperone-induced quasi-interdigitated lipid phase

por Tagaeva, Ruslana, Efimova, Svetlana, Ischenko, Alexander, Zhakhov, Alexander, Shevtsov, Maxim, Ostroumova, Olga
Publicado 2023

Pore-forming activity of new conjugate antibiotics based on amphotericin B

por Efimova, Svetlana S., Tevyashova, Anna N., Olsufyeva, Evgenia N., Bykov, Evgeny E., Ostroumova, Olga S.
Publicado 2017

Blocking ion channels induced by antifungal lipopeptide syringomycin E with amide-linked local anesthetics

por Zakharova, Anastasiia A., Efimova, Svetlana S., Schagina, Ludmila V., Malev, Valery V., Ostroumova, Olga S.
Publicado 2018

1,3-Thiazine, 1,2,3,4-Dithiadiazole, and Thiohydrazide Derivatives Affect Lipid Bilayer Properties and Ion-Permeable Pores Induced by Antifungals

por Zakharova, Anastasiia A., Efimova, Svetlana S., Yuskovets, Valeriy N., Yakovlev, Igor P., Sarkisyan, Zara M., Ostroumova, Olga S.
Publicado 2020

Plant Alkaloids Inhibit Membrane Fusion Mediated by Calcium and Fragments of MERS-CoV and SARS-CoV/SARS-CoV-2 Fusion Peptides

por Shekunov, Egor V., Efimova, Svetlana S., Yudintceva, Natalia M., Muryleva, Anna A., Zarubaev, Vladimir V., Slita, Alexander V., Ostroumova, Olga S.
Publicado 2021

Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress

por Efimova, Svetlana S., Martynyuk, Vera A., Zakharova, Anastasiia A., Yudintceva, Natalia M., Chernov, Nikita M., Yakovlev, Igor P., Ostroumova, Olga S.
Publicado 2022

Cyclic lipopeptides as membrane fusion inhibitors against SARS-CoV-2: New tricks for old dogs

por Shekunov, Egor V., Zlodeeva, Polina D., Efimova, Svetlana S., Muryleva, Anna A., Zarubaev, Vladimir V., Slita, Alexander V., Ostroumova, Olga S.
Publicado 2023

Semisynthetic Amides of Amphotericin B and Nystatin A(1): A Comparative Study of In Vitro Activity/Toxicity Ratio in Relation to Selectivity to Ergosterol Membranes

por Tevyashova, Anna, Efimova, Svetlana, Alexandrov, Alexander, Omelchuk, Olga, Ghazy, Eslam, Bychkova, Elena, Zatonsky, Georgy, Grammatikova, Natalia, Dezhenkova, Lyubov, Solovieva, Svetlana, Ostroumova, Olga, Shchekotikhin, Andrey
Publicado 2023