Editorial: The notch signaling pathway in lymphoid malignancies

por Fais, Franco, Efremov, Dimitar G.
Publicado 2023

Therapeutic Targets in Chronic Lymphocytic Leukemia

por Laurenti, Luca, Efremov, Dimitar G.
Publicado 2020

Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL

por Efremov, Dimitar G., Wiestner, Adrian, Laurenti, Luca
Publicado 2012

Mechanisms of B Cell Receptor Activation and Responses to B Cell Receptor Inhibitors in B Cell Malignancies

por Efremov, Dimitar G., Turkalj, Sven, Laurenti, Luca
Publicado 2020

New developments in the management of chronic lymphocytic leukemia: role of ofatumumab

por Laurenti, Luca, Innocenti, Idanna, Autore, Francesco, Sica, Simona, Efremov, Dimitar G
Publicado 2016

The Two Membrane Isoforms of Human IgE Assemble into Functionally Distinct B Cell Antigen Receptors

por Batista, Facundo D., Anand, Shubha, Presani, Gianni, Efremov, Dimitar G., Burrone, Oscar R.
Publicado 1996

The Use of Monoclonal Antibodies in the Treatment of Autoimmune Complications of Chronic Lymphocytic Leukemia

por Laurenti, Luca, Vannata, Barbara, Innocenti, Idanna, Autore, Francesco, Santini, Francesco, Sica, Simona, Efremov, Dimitar G.
Publicado 2013

Chlorambucil plus Rituximab as Front-Line Therapy in Elderly/Unfit Patients Affected by B-Cell Chronic Lymphocytic Leukemia: Results of a Single-Centre Experience

por Laurenti, Luca, Vannata, Barbara, Innocenti, Idanna, Autore, Francesco, Santini, Francesco, Piccirillo, Nicola, Za, Tommaso, Bellesi, Silvia, Marietti, Sara, Sica, Simona, Efremov, Dimitar G., Leone, Giuseppe
Publicado 2013

ABT‐199 (Venetoclax), a BH3‐mimetic Bcl‐2 inhibitor, does not cause Ca(2+)‐signalling dysregulation or toxicity in pancreatic acinar cells

por Jakubowska, Monika A, Kerkhofs, Martijn, Martines, Claudio, Efremov, Dimitar G, Gerasimenko, Julia V, Gerasimenko, Oleg V, Petersen, Ole H, Bultynck, Geert, Vervliet, Tim, Ferdek, Pawel E
Publicado 2018

Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance

por Dal-Bo, Michele, Bertoni, Francesco, Forconi, Francesco, Zucchetto, Antonella, Bomben, Riccardo, Marasca, Roberto, Deaglio, Silvia, Laurenti, Luca, Efremov, Dimitar G, Gaidano, Gianluca, Del Poeta, Giovanni, Gattei, Valter
Publicado 2009

Genotype-phenotype association analysis identifies the role of α globin genes in modulating disease severity of β thalassaemia intermedia in Sri Lanka

por Perera, Shiromi, Allen, Angela, Silva, Ishari, Hapugoda, Menaka, Wickramarathne, M. Nirmali, Wijesiriwardena, Indira, Allen, Stephen, Rees, David, Efremov, Dimitar G., Fisher, Christopher A., Weatherall, David J., Premawardhena, Anuja
Publicado 2019

Prevalence of Allelic Variants and Clonality of IGHV1-69 Expressing B-Cells in Patients with Different Severity of COVID 19 Disease

por Panovska-Stavridis, Irina, Ridova, Nevenka, Stojanovska, Simona, Stevanovic, Milena, Stojanoska, Tatjana, Demiri, Ilir, Matevska-Geshkovska, Nadica, Vujovic, Marija, Markoska, Hristina, Filipce, Venko, Dimovski, Aleksandar J., Efremov, Dimitar G
Publicado 2021

Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia

por Vitale, Candida, Griggio, Valentina, Todaro, Maria, Riganti, Chiara, Jones, Rebecca, Boccellato, Elia, Perutelli, Francesca, Arruga, Francesca, Vaisitti, Tiziana, Efremov, Dimitar G., Deaglio, Silvia, Landesman, Yosef, Bruno, Benedetto, Coscia, Marta
Publicado 2023

Multiple Distinct Sets of Stereotyped Antigen Receptors Indicate a Role for Antigen in Promoting Chronic Lymphocytic Leukemia

por Messmer, Bradley T., Albesiano, Emilia, Efremov, Dimitar G., Ghiotto, Fabio, Allen, Steven L., Kolitz, Jonathan, Foa, Robin, Damle, Rajendra N., Fais, Franco, Messmer, Davorka, Rai, Kanti R., Ferrarini, Manlio, Chiorazzi, Nicholas
Publicado 2004

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic...

por Bulian, Pietro, Rossi, Davide, Forconi, Francesco, Del Poeta, Giovanni, Bertoni, Francesco, Zucca, Emanuele, Montillo, Marco, Pozzato, Gabriele, D'Arena, Giovanni, Efremov, Dimitar G, Marasca, Roberto, Lauria, Francesco, Gaidano, Gianluca, Gattei, Valter, Laurenti, Luca
Publicado 2012

Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens

por Jiménez de Oya, Nereida, De Giovanni, Marco, Fioravanti, Jessica, Übelhart, Rudolf, Di Lucia, Pietro, Fiocchi, Amleto, Iacovelli, Stefano, Efremov, Dimitar G, Caligaris‐Cappio, Federico, Jumaa, Hassan, Ghia, Paolo, Guidotti, Luca G, Iannacone, Matteo
Publicado 2017

BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models

por Vervloessem, Tamara, Sasi, Binu K., Xerxa, Elena, Karamanou, Spyridoula, Kale, Justin, La Rovere, Rita M., Chakraborty, Supriya, Sneyers, Flore, Vogler, Meike, Economou, Anastassios, Laurenti, Luca, Andrews, David W., Efremov, Dimitar G., Bultynck, Geert
Publicado 2020

The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells

por Dal Bo, Michele, D'Agaro, Tiziana, Gobessi, Stefania, Zucchetto, Antonella, Dereani, Sara, Rossi, Davide, Zaja, Francesco, Pozzato, Gabriele, Di Raimondo, Francesco, Gaidano, Gianluca, Laurenti, Luca, Del Poeta, Giovanni, Efremov, Dimitar G., Gattei, Valter, Bomben, Riccardo
Publicado 2015

CD200 and Chronic Lymphocytic Leukemia: Biological and Clinical Relevance

por D’Arena, Giovanni, De Feo, Vincenzo, Pietrantuono, Giuseppe, Seneca, Elisa, Mansueto, Giovanna, Villani, Oreste, La Rocca, Francesco, D’Auria, Fiorella, Statuto, Teodora, Valvano, Luciana, Arruga, Francesca, Deaglio, Silvia, Efremov, Dimitar G., Sgambato, Alessandro, Laurenti, Luca
Publicado 2020

A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia

por Goral, Agnieszka, Firczuk, Malgorzata, Fidyt, Klaudyna, Sledz, Marta, Simoncello, Francesca, Siudakowska, Karolina, Pagano, Giulia, Moussay, Etienne, Paggetti, Jérôme, Nowakowska, Patrycja, Gobessi, Stefania, Barankiewicz, Joanna, Salomon-Perzynski, Aleksander, Benvenuti, Federica, Efremov, Dimitar G., Juszczynski, Przemyslaw, Lech-Maranda, Ewa, Muchowicz, Angelika
Publicado 2022