Somatic selection distinguishes oncogenes and tumor suppressor genes

por Chandrashekar, Pramod, Ahmadinejad, Navid, Wang, Junwen, Sekulic, Aleksandar, Egan, Jan B, Asmann, Yan W, Kumar, Sudhir, Maley, Carlo, Liu, Li
Publicado 2019

PANDA: pathway and annotation explorer for visualizing and interpreting gene-centric data

por Hart, Steven N., Moore, Raymond M., Zimmermann, Michael T., Oliver, Gavin R., Egan, Jan B., Bryce, Alan H., Kocher, Jean-Pierre A.
Publicado 2015

Oncolytic virotherapy in upper gastrointestinal tract cancers

por Yokoda, Raquel, Nagalo, Bolni M, Arora, Mansi, Egan, Jan B, Bogenberger, James M, DeLeon, Thomas T, Zhou, Yumei, Ahn, Daniel H, Borad, Mitesh J
Publicado 2018

Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect

por Yokoda, Raquel, Nagalo, Bolni M, Vernon, Brent, Oklu, Rahmi, Albadawi, Hassan, DeLeon, Thomas T, Zhou, Yumei, Egan, Jan B, Duda, Dan G, Borad, Mitesh J
Publicado 2017

Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet

por Myers, Cheryl E., Hoelzinger, Dominique B., Truong, Tiffany N., Chew, Lindsey A., Myles, Arpita, Chaudhuri, Leena, Egan, Jan B., Liu, Jun, Gendler, Sandra J., Cohen, Peter A.
Publicado 2017

Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing

por Bryce, Alan H., Egan, Jan B., Smadbeck, James B., Johnson, Sarah H., Murphy, Stephen J., Harris, Faye R., Halling, Geoffrey C., Terra, Simone B. S. P., Cheville, John, Pagliaro, Lance, Leibovich, Brad, Costello, Brian A., Vasmatzis, George
Publicado 2019

Differential impact of tumor suppressor gene (TP53, PTEN, RB1) alterations and treatment outcomes in metastatic, hormone-sensitive prostate cancer

por Velez, Miguel Gonzalez, Kosiorek, Heidi E., Egan, Jan B., McNatty, Andrea L., Riaz, Irbaz B., Hwang, Steven R., Stewart, Glenn A., Ho, Thai H., Moore, Cassandra N., Singh, Parminder, Sharpsten, Renee K., Costello, Brian A., Bryce, Alan H.
Publicado 2021

Whole Genome Analyses of a Well-Differentiated Liposarcoma Reveals Novel SYT1 and DDR2 Rearrangements

por Egan, Jan B., Barrett, Michael T., Champion, Mia D., Middha, Sumit, Lenkiewicz, Elizabeth, Evers, Lisa, Francis, Princy, Schmidt, Jessica, Shi, Chang-Xin, Van Wier, Scott, Badar, Sandra, Ahmann, Gregory, Kortuem, K. Martin, Boczek, Nicole J., Fonseca, Rafael, Craig, David W., Carpten, John D., Borad, Mitesh J., Stewart, A. Keith
Publicado 2014

Simultaneous Characterization of Somatic Events and HPV-18 Integration in a Metastatic Cervical Carcinoma Patient Using DNA and RNA Sequencing

por Liang, Winnie S., Aldrich, Jessica, Nasser, Sara, Kurdoglu, Ahmet, Phillips, Lori, Reiman, Rebecca, McDonald, Jacquelyn, Izatt, Tyler, Christoforides, Alexis, Baker, Angela, Craig, Christine, Egan, Jan B., Chase, Dana M., Farley, John H., Bryce, Alan H., Stewart, A. Keith, Borad, Mitesh J., Carpten, John D., Craig, David W., Monk, Bradley J.
Publicado 2014

Comparison of germline mutations in African American and Caucasian men with metastatic prostate cancer

por Ledet, Elisa M., Burgess, Earle F., Sokolova, Alexandra O., Jaeger, Ellen B., Hatton, Whitley, Moses, Marcus, Miller, Patrick, Cotogno, Patrick, Layton, Jodi, Barata, Pedro, Lewis, Brian E., Nakazawa, Mari, Zhu, Jason, Dellinger, Beth, Elrefai, Sara, Nafissi, Nellie N., Egan, Jan B., Shore, Neal, McKay, Rana R., Bryce, Alan H., Cheng, Heather H., Antonarakis, Emmanuel S., Sartor, Oliver
Publicado 2021

LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth

por Oliver, Gavin R., Marcano-Bonilla, Sofia, Quist, Jonathan, Tolosa, Ezequiel J., Iguchi, Eriko, Swanson, Amy A., Hoppman, Nicole L., Schwab, Tanya, Sigafoos, Ashley, Prodduturi, Naresh, Voss, Jesse S., Knight, Shannon M., Zhang, Jin, Fadra, Numrah, Urrutia, Raul, Zimmerman, Michael, Egan, Jan B., Bilyeu, Anthony G., Jen, Jin, Veras, Ema, Al-Safi, Rema’a, Block, Matthew, Kerr, Sarah, Fernandez-Zapico, Martin E., Schoolmeester, John K., Klee, Eric W.
Publicado 2021

Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing

por Liang, Winnie S., Craig, David W., Carpten, John, Borad, Mitesh J., Demeure, Michael J., Weiss, Glen J., Izatt, Tyler, Sinari, Shripad, Christoforides, Alexis, Aldrich, Jessica, Kurdoglu, Ahmet, Barrett, Michael, Phillips, Lori, Benson, Hollie, Tembe, Waibhav, Braggio, Esteban, Kiefer, Jeffrey A., Legendre, Christophe, Posner, Richard, Hostetter, Galen H., Baker, Angela, Egan, Jan B., Han, Haiyong, Lake, Douglas, Stites, Edward C., Ramanathan, Ramesh K., Fonseca, Rafael, Stewart, A. Keith, Von Hoff, Daniel
Publicado 2012

Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

por Bryce, Alan H., Egan, Jan B., Borad, Mitesh J., Stewart, A. Keith, Nowakowski, Grzegorz S., Chanan-Khan, Asher, Patnaik, Mrinal M., Ansell, Stephen M., Banck, Michaela S., Robinson, Steven I., Mansfield, Aaron S., Klee, Eric W., Oliver, Gavin R., McCormick, Jennifer B., Huneke, Norine E., Tagtow, Colleen M., Jenkins, Robert B., Rumilla, Kandelaria M., Kerr, Sarah E., Kocher, Jean-Pierre A., Beck, Scott A., Fernandez-Zapico, Martin E., Farrugia, Gianrico, Lazaridis, Konstantinos N., McWilliams, Robert R.
Publicado 2017

Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment Wit...

por Bryce, Alan H., Borad, Mitesh J., Egan, Jan B., Condjella, Rachel M., Liang, Winnie S., Fonseca, Rafael, McCullough, Ann E., Hunt, Katherine S., Ritacca, Nicole R., Barrett, Michael T., Patel, Maitray D., Young, Scott W., Silva, Alvin C., Ho, Thai H., Halfdanarson, Thorvardur R., Stanton, Melissa L., Cheville, John, Swanson, Scott, Schneider, Daniel E., McWilliams, Robert R., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Cuyugan, Lori, McDonald, Jacquelyn, Adkins, Jonathan, Mastrian, Stephen D., Von Hoff, Daniel D., Craig, David W., Stewart, A. Keith, Carpten, John D.
Publicado 2016

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

por Borad, Mitesh J., Egan, Jan B., Condjella, Rachel M., Liang, Winnie S., Fonseca, Rafael, Ritacca, Nicole R., McCullough, Ann E., Barrett, Michael T., Hunt, Katherine S., Champion, Mia D., Patel, Maitray D., Young, Scott W., Silva, Alvin C., Ho, Thai H., Halfdanarson, Thorvardur R., McWilliams, Robert R., Lazaridis, Konstantinos N., Ramanathan, Ramesh K., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Cuyugan, Lori, McDonald, Jacquelyn, Adkins, Jonathan, Mastrian, Stephen D., Valdez, Riccardo, Jaroszewski, Dawn E., Von Hoff, Daniel D., Craig, David W., Stewart, A. Keith, Carpten, John D., Bryce, Alan H.
Publicado 2016

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

por Borad, Mitesh J., Champion, Mia D., Egan, Jan B., Liang, Winnie S., Fonseca, Rafael, Bryce, Alan H., McCullough, Ann E., Barrett, Michael T., Hunt, Katherine, Patel, Maitray D., Young, Scott W., Collins, Joseph M., Silva, Alvin C., Condjella, Rachel M., Block, Matthew, McWilliams, Robert R., Lazaridis, Konstantinos N., Klee, Eric W., Bible, Keith C., Harris, Pamela, Oliver, Gavin R., Bhavsar, Jaysheel D., Nair, Asha A., Middha, Sumit, Asmann, Yan, Kocher, Jean-Pierre, Schahl, Kimberly, Kipp, Benjamin R., Barr Fritcher, Emily G., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Phillips, Lori, McDonald, Jackie, Adkins, Jonathan, Mastrian, Stephen D., Placek, Pamela, Watanabe, Aprill T., LoBello, Janine, Han, Haiyong, Von Hoff, Daniel, Craig, David W., Stewart, A. Keith, Carpten, John D.
Publicado 2014

Molecular Modeling and Functional Analysis of Exome Sequencing–Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma

por Egan, Jan B., Marks, David L., Hogenson, Tara L., Vrabel, Anne M., Sigafoos, Ashley N., Tolosa, Ezequiel J., Carr, Ryan M., Safgren, Stephanie L., Enriquez Hesles, Elisa, Almada, Luciana L., Romecin-Duran, Paola A., Iguchi, Eriko, Ala’Aldeen, Aryan, Kocher, Jean-Pierre A., Oliver, Gavin R., Prodduturi, Naresh, Mead, David W., Hossain, Asif, Huneke, Norine E., Tagtow, Colleen M., Ailawadhi, Sikander, Ansell, Stephen M., Banck, Michaela S., Bryce, Alan H., Carballido, Estrella M., Chanan-Khan, Asher A., Curtis, Kelly K., Resnik, Ernesto, Gawryletz, Chelsea D., Go, Ronald S., Halfdanarson, Thorvardur R., Ho, Thai H., Joseph, Richard W., Kapoor, Prashant, Mansfield, Aaron S., Meurice, Nathalie, Nageswara Rao, Amulya A., Nowakowski, Grzegorz S., Pardanani, Animesh, Parikh, Sameer A., Cheville, John C., Feldman, Andrew L., Ramanathan, Ramesh K., Robinson, Steven I., Tibes, Raoul, Finnes, Heidi D., McCormick, Jennifer B., McWilliams, Robert R., Jatoi, Aminah, Patnaik, Mrinal M., Silva, Alvin C., Wieben, Eric D., McAllister, Tammy M., Rumilla, Kandelaria M., Kerr, Sarah E., Lazaridis, Konstantinos N., Farrugia, Gianrico, Stewart, A. Keith, Clark, Karl J., Kennedy, Eileen J., Klee, Eric W., Borad, Mitesh J., Fernandez-Zapico, Martin E.
Publicado 2017