Progression to Metastasis of Solid Cancer

por Zacksenhaus, Eldad, Egan, Sean E.
Publicado 2021

A Tumor initiating cell-enriched prognostic signature for HER2(+):ERα(−) breast cancer; rationale, new features, controversies and future directions

por Liu, Jeff C., Egan, Sean E., Zacksenhaus, Eldad
Publicado 2013

The tumor cell‐derived matrix of lobular breast cancer: a new vulnerability

por Kozma, Katelyn J, Done, Susan J, Egan, Sean E
Publicado 2021

Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation

por Liu, Jeff C., Wang, Dong-Yu, Egan, Sean E., Zacksenhaus, Eldad
Publicado 2016

Elevated PI3K signaling drives multiple Breast Cancer subtypes

por Adams, Jessica R., Schachter, Nathan F., Liu, Jeff C., Zacksenhaus, Eldad, Egan, Sean E.
Publicado 2011

Targeting HER2(+) breast cancer: the TBK1/IKKε axis

por Jiang, Zhe, Liu, Jeff C., Chung, Philip E.D., Egan, Sean E., Zacksenhaus, Eldad
Publicado 2014

Notch3 Is Dispensable for Thymocyte β-Selection and Notch1-Induced T Cell Leukemogenesis

por Suliman, Sara, Tan, Joanne, Xu, Keli, Kousis, Philaretos C., Kowalski, Paul E., Chang, Greg, Egan, Sean E., Guidos, Cynthia
Publicado 2011

High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: Interaction with IQ motif-containing factors

por Robinson, Tyler JW, Pai, Melody, Liu, Jeff C, Vizeacoumar, Frederick, Sun, Thomas, Egan, Sean E, Datti, Alessandro, Huang, Jing, Zacksenhaus, Eldad
Publicado 2013

Erratum to: Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

por Bane, Anita L., Pinnaduwage, Dushanthi, Colby, Sarah, Reedijk, Michael, Egan, Sean E., Bull, Shelley B., O’Malley, Frances P., Andrulis, Irene L.
Publicado 2009

RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs

por Robinson, Tyler J. W., Liu, Jeff C., Vizeacoumar, Frederick, Sun, Thomas, Maclean, Neil, Egan, Sean E., Schimmer, Aaron D., Datti, Alessandro, Zacksenhaus, Eldad
Publicado 2013

Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K

por Liu, Jeff C, Voisin, Veronique, Wang, Sharon, Wang, Dong-Yu, Jones, Robert A, Datti, Alessandro, Uehling, David, Al-awar, Rima, Egan, Sean E, Bader, Gary D, Tsao, Ming, Mak, Tak W, Zacksenhaus, Eldad
Publicado 2014

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

por Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Harrell, Joshua Chuck, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M
Publicado 2013

Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay

por Hammoud, Lamis, Adams, Jessica R., Loch, Amanda J., Marcellus, Richard C., Uehling, David E., Aman, Ahmed, Fladd, Christopher, McKee, Trevor D., Jo, Christine E.B., Al-Awar, Rima, Egan, Sean E., Rossant, Janet
Publicado 2016

The Chromatin Regulator Ankrd11 Controls Palate and Cranial Bone Development

por Roth, Daniela Marta, Baddam, Pranidhi, Lin, Haiming, Vidal-García, Marta, Aponte, Jose David, De Souza, Sarah-Thea, Godziuk, Devyn, Watson, Adrianne Eve Scovil, Footz, Tim, Schachter, Nathan F., Egan, Sean E., Hallgrímsson, Benedikt, Graf, Daniel, Voronova, Anastassia
Publicado 2021

Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer

por Liu, Jeff C., Granieri, Letizia, Shrestha, Mariusz, Wang, Dong-Yu, Vorobieva, Ioulia, Rubie, Elizabeth A., Jones, Rob, Ju, YoungJun, Pellecchia, Giovanna, Jiang, Zhe, Palmerini, Carlo A., Ben-David, Yaacov, Egan, Sean E., Woodgett, James R., Bader, Gary D., Datti, Alessandro, Zacksenhaus, Eldad
Publicado 2018

Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer

por Jiang, Zhe, Ju, YoungJun, Ali, Amjad, Chung, Philip E. D., Skowron, Patryk, Wang, Dong-Yu, Shrestha, Mariusz, Li, Huiqin, Liu, Jeff C., Vorobieva, Ioulia, Ghanbari-Azarnier, Ronak, Mwewa, Ethel, Koritzinsky, Marianne, Ben-David, Yaacov, Woodgett, James R., Perou, Charles M., Dupuy, Adam, Bader, Gary D., Egan, Sean E., Taylor, Michael D., Zacksenhaus, Eldad
Publicado 2023

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

por An, Yeji, Adams, Jessica R., Hollern, Daniel P., Zhao, Anthony, Chang, Stephen G., Gams, Miki S., Chung, Philip E.D., He, Xiaping, Jangra, Rhea, Shah, Juhi S., Yang, Joanna, Beck, Lauren A., Raghuram, Nandini, Kozma, Katelyn J., Loch, Amanda J., Wang, Wei, Fan, Cheng, Done, Susan J., Zacksenhaus, Eldad, Guidos, Cynthia J., Perou, Charles M., Egan, Sean E.
Publicado 2018

Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer

por Schachter, Nathan F., Adams, Jessica R., Skowron, Patryk, Kozma, Katelyn. J., Lee, Christian A., Raghuram, Nandini, Yang, Joanna, Loch, Amanda J., Wang, Wei, Kucharczuk, Aaron, Wright, Katherine L., Quintana, Rita M., An, Yeji, Dotzko, Daniel, Gorman, Jennifer L., Wojtal, Daria, Shah, Juhi S., Leon-Gomez, Paul, Pellecchia, Giovanna, Dupuy, Adam J., Perou, Charles M., Ben-Porath, Ittai, Karni, Rotem, Zacksenhaus, Eldad, Woodgett, Jim R., Done, Susan J., Garzia, Livia, Sorana Morrissy, A., Reimand, Jüri, Taylor, Michael D., Egan, Sean E.
Publicado 2021