Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment

por O’Brien, Sarah A., Orf, Jessica, Skrzypczynska, Katarzyna M., Tan, Hong, Kim, Jennie, DeVoss, Jason, Belmontes, Brian, Egen, Jackson G.
Publicado 2021

Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies

por Noe, Paul, Wang, Joy H., Chung, Kyu, Cheng, Zhiyong, Field, Jessica J., Shen, Xiaomeng, Cortesio, Christa L., Pastuskovas, Cinthia V., Phee, Hyewon, Tarbell, Kristin V., Egen, Jackson G., Casbon, Amy-Jo
Publicado 2023

Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity

por Kim, Jennie C., Liu, Xian, Fitzgerald, Karen, Eng, Jason S., Orf, Jessica, O’Brien, Sarah A., Belmontes, Brian, Casbon, Amy-Jo, Novitskiy, Sergey V., Tarbell, Kristin V., DeVoss, Jason, Egen, Jackson G.
Publicado 2022

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

por Rutgeerts, Paul J, Fedorak, Richard N, Hommes, Daan W, Sturm, Andreas, Baumgart, Daniel C, Bressler, Brian, Schreiber, Stefan, Mansfield, John C, Williams, Marna, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Keir, Mary, Luca, Diana, Danilenko, Dimitri, Egen, Jackson, O'Byrne, Sharon
Publicado 2013

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

por Lamb, Christopher A., Mansfield, John C., Tew, Gaik W., Gibbons, Deena, Long, Anna K., Irving, Peter, Diehl, Lauri, Eastham-Anderson, Jeff, Price, Maria B., O’Boyle, Graeme, Jones, David E. J., O’Byrne, Sharon, Hayday, Adrian, Keir, Mary E., Egen, Jackson G., Kirby, John A.
Publicado 2017

Autonomous IL-36R signaling in neutrophils activates potent antitumor effector functions

por Roy, Sumedha, Fitzgerald, Karen, Lalani, Almin, Lai, Chin-Wen, Kim, Aeryon, Kim, Jennie, Ou, Peiqi, Mirsoian, Annie, Liu, Xian, Ramrakhiani, Ambika, Zhao, Huiren, Zhou, Hong, Xu, Haoda, Meisen, Hans, Li, Chi-Ming, Lugt, Bryan Vander, Thibault, Steve, Tinberg, Christine E., DeVoss, Jason, Egen, Jackson, Wu, Lawren C., Noubade, Rajkumar
Publicado 2023

Functional Consequences of the Macrophage Stimulating Protein 689C Inflammatory Bowel Disease Risk Allele

por Kauder, Steven E., Santell, Lydia, Mai, Elaine, Wright, Lilyan Y., Luis, Elizabeth, N'Diaye, Elsa N., Lutman, Jeff, Ratti, Navneet, Sa, Susan M., Maun, Henry R., Stefanich, Eric, Gonzalez, Lino C., Graham, Robert R., Diehl, Lauri, Faubion, William A., Keir, Mary E., Young, Judy, Chaudhuri, Amitabha, Lazarus, Robert A., Egen, Jackson G.
Publicado 2013