Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies

por Glez-Vaz, Javier, Azpilikueta, Arantza, Olivera, Irene, Cirella, Assunta, Teijeira, Alvaro, Ochoa, Maria C, Alvarez, Maite, Eguren-Santamaria, Iñaki, Luri-Rey, Carlos, Rodriguez-Ruiz, Maria E, Nie, Xinxin, Chen, Lieping, Guedan, Sonia, Sanmamed, Miguel F, Luis Perez Gracia, Jose, Melero, Ignacio
Publicado 2022

Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists

por Cirella, Assunta, Bolaños, Elixabet, Luri-Rey, Carlos, Di Trani, Claudia Augusta, Olivera, Irene, Gomis, Gabriel, Glez-Vaz, Javier, Pinci, Beatrice, Garasa, Saray, Sánchez-Gregorio, Sandra, Azpilikueta, Arantza, Eguren-Santamaria, Iñaki, Valencia, Karmele, Palencia, Belén, Alvarez, Maite, Ochoa, Maria C., Teijeira, Álvaro, Berraondo, Pedro, Melero, Ignacio
Publicado 2023

mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy

por Olivera, Irene, Bolaños, Elixabet, Gonzalez-Gomariz, Jose, Hervas-Stubbs, Sandra, Mariño, Karina V., Luri-Rey, Carlos, Etxeberria, Iñaki, Cirella, Assunta, Egea, Josune, Glez-Vaz, Javier, Garasa, Saray, Alvarez, Maite, Eguren-Santamaria, Iñaki, Guedan, Sonia, Sanmamed, Miguel F., Berraondo, Pedro, Rabinovich, Gabriel A., Teijeira, Alvaro, Melero, Ignacio
Publicado 2023