Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production

por Piel, Sarah, Ehinger, Johannes K., Chamkha, Imen, Frostner, Eleonor Åsander, Sjövall, Fredrik, Elmér, Eskil, Hansson, Magnus J.
Publicado 2018

Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose

por Piel, Sarah, Chamkha, Imen, Dehlin, Adam Kozak, Ehinger, Johannes K., Sjövall, Fredrik, Elmér, Eskil, Hansson, Magnus J.
Publicado 2020

Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity

por Avram, Vlad F., Chamkha, Imen, Åsander-Frostner, Eleonor, Ehinger, Johannes K., Timar, Romulus Z., Hansson, Magnus J., Muntean, Danina M., Elmér, Eskil
Publicado 2021

Predictors of outcome in children with disorders of mitochondrial metabolism in the pediatric intensive care unit

por Ehinger, Johannes K., Karlsson, Michael, Sjövall, Fredrik, Leffler, Märta, McCormack, Shana E., Kubis, Sherri E., Åkesson, Anna, Falk, Marni J., Kilbaugh, Todd J.
Publicado 2021

Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Amiodarone Toxicity

por Bețiu, Alina M., Chamkha, Imen, Gustafsson, Ellen, Meijer, Elna, Avram, Vlad F., Åsander Frostner, Eleonor, Ehinger, Johannes K., Petrescu, Lucian, Muntean, Danina M., Elmér, Eskil
Publicado 2021

Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury

por Karlsson, Michael, Pukenas, Bryan, Chawla, Sanjeev, Ehinger, Johannes K., Plyler, Ross, Stolow, Madeline, Gabello, Melissa, Hugerth, Matilda, Elmér, Eskil, Hansson, Magnus J., Margulies, Susan, Kilbaugh, Todd
Publicado 2019

In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning

por Owiredu, Shawn, Ranganathan, Abhay, Greenwood, John C., Piel, Sarah, Janowska, Joanna I., Eckmann, David M., Kelly, Matthew, Ehinger, Johannes K., Kilbaugh, Todd J., Jang, David H.
Publicado 2020

Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons

por Galera-Monge, Teresa, Zurita-Díaz, Francisco, Canals, Isaac, Grønning Hansen, Marita, Rufián-Vázquez, Laura, Ehinger, Johannes K., Elmér, Eskil, Martin, Miguel A., Garesse, Rafael, Ahlenius, Henrik, Gallardo, M. Esther
Publicado 2020

Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency

por Ehinger, Johannes K., Piel, Sarah, Ford, Rhonan, Karlsson, Michael, Sjövall, Fredrik, Frostner, Eleonor Åsander, Morota, Saori, Taylor, Robert W., Turnbull, Doug M., Cornell, Clive, Moss, Steven J., Metzsch, Carsten, Hansson, Magnus J., Fliri, Hans, Elmér, Eskil
Publicado 2016

Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning

por Piel, Sarah, Janowska, Joanna I., Ward, J. Laurenson, McManus, Meagan J., Jose, Joshua S., Starr, Jonathan, Sheldon, Malkah, Clayman, Carly L., Elmér, Eskil, Hansson, Magnus J., Jang, David H., Karlsson, Michael, Ehinger, Johannes K., Kilbaugh, Todd J.
Publicado 2022