Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells

por Lieb, Simone, Blaha-Ostermann, Silvia, Kamper, Elisabeth, Rippka, Janine, Schwarz, Cornelia, Ehrenhöfer-Wölfer, Katharina, Schlattl, Andreas, Wernitznig, Andreas, Lipp, Jesse J, Nagasaka, Kota, van der Lelij, Petra, Bader, Gerd, Koi, Minoru, Goel, Ajay, Neumüller, Ralph A, Peters, Jan-Michael, Kraut, Norbert, Pearson, Mark A, Petronczki, Mark, Wöhrle, Simon
Publicado 2019

SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines

por Ehrenhöfer-Wölfer, Katharina, Puchner, Teresa, Schwarz, Cornelia, Rippka, Janine, Blaha-Ostermann, Silvia, Strobl, Ursula, Hörmann, Alexandra, Bader, Gerd, Kornigg, Stefan, Zahn, Stephan, Sommergruber, Wolfgang, Schweifer, Norbert, Zichner, Thomas, Schlattl, Andreas, Neumüller, Ralph A., Shi, Junwei, Vakoc, Christopher R., Kögl, Manfred, Petronczki, Mark, Kraut, Norbert, Pearson, Mark A., Wöhrle, Simon
Publicado 2019

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

por Farnaby, William, Koegl, Manfred, Roy, Michael J., Whitworth, Claire, Diers, Emelyne, Trainor, Nicole, Zollman, David, Steurer, Steffen, Karolyi-Oezguer, Jale, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Galant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Gerstberger, Thomas, Schnitzer, Renate, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Ehrenhöfer-Wölfer, Katharina, Wöhrle, Simon, Boehmelt, Guido, Rinnenthal, Joerg, Arnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio
Publicado 2019