A generic selection system for improved expression and thermostability of G protein-coupled receptors by directed evolution

por Klenk, Christoph, Ehrenmann, Janosch, Schütz, Marco, Plückthun, Andreas
Publicado 2016

Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies

por Waltenspühl, Yann, Ehrenmann, Janosch, Klenk, Christoph, Plückthun, Andreas
Publicado 2021

Crystal structure of the human oxytocin receptor

por Waltenspühl, Yann, Schöppe, Jendrik, Ehrenmann, Janosch, Kummer, Lutz, Plückthun, Andreas
Publicado 2020

Structural basis for the activation and ligand recognition of the human oxytocin receptor

por Waltenspühl, Yann, Ehrenmann, Janosch, Vacca, Santiago, Thom, Cristian, Medalia, Ohad, Plückthun, Andreas
Publicado 2022

Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists

por Schöppe, Jendrik, Ehrenmann, Janosch, Klenk, Christoph, Rucktooa, Prakash, Schütz, Marco, Doré, Andrew S., Plückthun, Andreas
Publicado 2019

Structures of neurokinin 1 receptor in complex with G(q) and G(s) proteins reveal substance P binding mode and unique activation features

por Thom, Cristian, Ehrenmann, Janosch, Vacca, Santiago, Waltenspühl, Yann, Schöppe, Jendrik, Medalia, Ohad, Plückthun, Andreas
Publicado 2021

Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts

por Schütz, Marco, Schöppe, Jendrik, Sedlák, Erik, Hillenbrand, Matthias, Nagy-Davidescu, Gabriela, Ehrenmann, Janosch, Klenk, Christoph, Egloff, Pascal, Kummer, Lutz, Plückthun, Andreas
Publicado 2016