Demonstration of the Antitumor Activity of the iNKT Agonist ABX196, a Novel Enhancer of Cancer Immunotherapy, in Melanoma and Hepatocarcinoma Mouse Models

por Scherrer, Didier, Barrett, Noel, Teyton, Luc, Pearce, Tillman, Nitcheu, Josianne, Pouletty, Philippe, Santo, Julien, Ehrlich, Hartmut J.
Publicado 2022

The Anti-Hiv Candidate Abx464 Dampens Intestinal Inflammation by Triggering Il-22 Production in Activated Macrophages

por Chebli, Karim, Papon, Laura, Paul, Conception, Garcel, Aude, Campos, Noëlie, Scherrer, Didier, J. Ehrlich, Hartmut, Hahne, Michael, Tazi, Jamal
Publicado 2017

RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation

por Manchon, Laurent, Chebli, Karim, Papon, Laura, Paul, Conception, Garcel, Aude, Campos, Noëlie, Scherrer, Didier, Ehrlich, Hartmut, Hahne, Michael, Tazi, Jamal
Publicado 2017

H5N1 Whole-Virus Vaccine Induces Neutralizing Antibodies in Humans Which Are Protective in a Mouse Passive Transfer Model

por Howard, M. Keith, Sabarth, Nicolas, Savidis-Dacho, Helga, Portsmouth, Daniel, Kistner, Otfried, Kreil, Thomas R., Ehrlich, Hartmut J., Barrett, P. Noel
Publicado 2011

ABX464 (obefazimod) for patients with COVID-19 at risk for severe disease: miR-AGE, a randomized, double-blind placebo-controlled trial

por Giavina-Bianchi, Pedro, Cua, Eric, Risso, Karine, Mondain, Véronique, Vissian, Anaïs, Joie, Cécile, Pouletty, Philippe, Gineste, Paul, Ehrlich, Hartmut J., Kalil, Jorge
Publicado 2023

Anti-amyloidogenic Activity of IgGs Contained in Normal Plasma

por O’Nuallain, Brian, Williams, Angela D., McWilliams-Koeppen, Helen P., Acero, Luis, Weber, Alfred, Ehrlich, Hartmut, Schwarz, Hans P., Solomon, Alan
Publicado 2010

Safety, Pharmacokinetics, and Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment-Naive HIV-Infected Subjects in a Phase 2 Randomized, Controlled Study

por Steens, Jean-Marc, Scherrer, Didier, Gineste, Paul, Barrett, P. Noel, Khuanchai, Supparatpino, Winai, Ratanasuwan, Ruxrungtham, Kiat, Tazi, Jamal, Murphy, Robert, Ehrlich, Hartmut
Publicado 2017

ABX464 (Obefazimod) Upregulates miR-124 to Reduce Proinflammatory Markers in Inflammatory Bowel Diseases

por Apolit, Cécile, Campos, Noëlie, Vautrin, Audrey, Begon-Pescia, Christina, Lapasset, Laure, Scherrer, Didier, Gineste, Paul, Ehrlich, Hartmut, Garcel, Aude, Santo, Julien, Tazi, Jamal
Publicado 2022

Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phas...

por Rutsaert, Sofie, Steens, Jean-Marc, Gineste, Paul, Cole, Basiel, Kint, Sam, Barrett, P Noel, Tazi, Jamal, Scherrer, Didier, Ehrlich, Hartmut J, Vandekerckhove, Linos
Publicado 2019

Safety and efficacy of the miR-124 upregulator ABX464 (obefazimod, 50 and 100 mg per day) in patients with active rheumatoid arthritis and inadequate response to methotrexate and/o...

por Daien, Claire, Krogulec, Marek, Gineste, Paul, Steens, Jean-Marc, Desroys du Roure, Laurence, Biguenet, Sophie, Scherrer, Didier, Santo, Julien, Ehrlich, Hartmut, Durez, Patrick
Publicado 2022

A Cell Culture–Derived Influenza Vaccine Provides Consistent Protection Against Infection and Reduces the Duration and Severity of Disease in Infected Individuals

por Ehrlich, Hartmut J., Singer, Julia, Berezuk, Gregory, Fritsch, Sandor, Aichinger, Gerald, Hart, Mary Kate, El-Amin, Wael, Portsmouth, Daniel, Kistner, Otfried, Barrett, P. Noel
Publicado 2012

Hyperimmune intravenous immunoglobulin containing high titers of pandemic H1N1 hemagglutinin and neuraminidase antibodies provides dose-dependent protection against lethal virus ch...

por Hohenadl, Christine, Wodal, Walter, Kerschbaum, Astrid, Fritz, Richard, Howard, M Keith, Farcet, Maria R, Portsmouth, Daniel, McVey, John K, Baker, Donald A, Ehrlich, Hartmut J, Barrett, P Noel, Kreil, Thomas R
Publicado 2014

Vectors Based on Modified Vaccinia Ankara Expressing Influenza H5N1 Hemagglutinin Induce Substantial Cross-Clade Protective Immunity

por Hessel, Annett, Schwendinger, Michael, Holzer, Georg W., Orlinger, Klaus K., Coulibaly, Sogue, Savidis-Dacho, Helga, Zips, Marie-Luise, Crowe, Brian A., Kreil, Thomas R., Ehrlich, Hartmut J., Barrett, P. Noel, Falkner, Falko G.
Publicado 2011

Human Anti-Aβ IgGs Target Conformational Epitopes on Synthetic Dimer Assemblies and the AD Brain-Derived Peptide

por Welzel, Alfred T., Williams, Angela D., McWilliams-Koeppen, Helen P., Acero, Luis, Weber, Alfred, Blinder, Veronika, Mably, Alex, Bunk, Sebastian, Hermann, Corinna, Farrell, Michael A., Ehrlich, Hartmut J., Schwarz, Hans P., Walsh, Dominic M., Solomon, Alan, O’Nuallain, Brian
Publicado 2012

A Whole Virus Pandemic Influenza H1N1 Vaccine Is Highly Immunogenic and Protective in Active Immunization and Passive Protection Mouse Models

por Kistner, Otfried, Crowe, Brian A., Wodal, Walter, Kerschbaum, Astrid, Savidis-Dacho, Helga, Sabarth, Nicolas, Falkner, Falko G., Mayerhofer, Ines, Mundt, Wolfgang, Reiter, Manfred, Grillberger, Leopold, Tauer, Christa, Graninger, Michael, Sachslehner, Alois, Schwendinger, Michael, Brühl, Peter, Kreil, Thomas R., Ehrlich, Hartmut J., Barrett, P. Noel
Publicado 2010