Loss of the Nuclear Protein RTF2 Enhances Influenza Virus Replication

por Chia, Bing Shao, Li, Bo, Cui, Ang, Eisenhaure, Thomas, Raychowdhury, Raktima, Lieb, David, Hacohen, Nir
Publicado 2020

Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation

por Lan, Yuk Yuen, Heather, James M., Eisenhaure, Thomas, Garris, Christopher Stuart, Lieb, David, Raychowdhury, Raktima, Hacohen, Nir
Publicado 2019

Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

por Gat-Viks, Irit, Chevrier, Nicolas, Wilentzik, Roni, Eisenhaure, Thomas, Raychowdhury, Raktima, Steuerman, Yael, Shalek, Alex, Hacohen, Nir, Amit, Ido, Regev, Aviv
Publicado 2013

Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures

por Reyes, Miguel, Vickers, Dwayne, Billman, Kianna, Eisenhaure, Thomas, Hoover, Paul, Browne, Edward P., Rao, Deepak A., Hacohen, Nir, Blainey, Paul C.
Publicado 2019

1830. Single-cell Transcriptional Profiling Reveals an Immune Cell State Signature of Bacterial Sepsis

por Reyes, Miguel, Bhattacharyya, Roby P, Filbin, Michael, Billman, Kianna, Eisenhaure, Thomas, Hung, Deborah T, Levy, Bruce, Baron, Rebecca, Blainey, Paul, Goldberg, Marcia B, Hacohen, Nir
Publicado 2019

SLAMF6​ deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint

por Hajaj, Emma, Eisenberg, Galit, Klein, Shiri, Frankenburg, Shoshana, Merims, Sharon, Ben David, Inna, Eisenhaure, Thomas, Henrickson, Sarah E, Villani, Alexandra Chloé, Hacohen, Nir, Abudi, Nathalie, Abramovich, Rinat, Cohen, Jonathan E, Peretz, Tamar, Veillette, Andre, Lotem, Michal
Publicado 2020

A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression

por Mahoney, Kathleen M., Shukla, Sachet A., Patsoukis, Nikolaos, Chaudhri, Apoorvi, Browne, Edward P., Arazi, Arnon, Eisenhaure, Thomas M., Pendergraft, William F., Hua, Ping, Pham, Hung C., Bu, Xia, Zhu, Baogong, Hacohen, Nir, Fritsch, Edward F., Boussiotis, Vassiliki A., Wu, Catherine J., Freeman, Gordon J.
Publicado 2018

Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

por Li, Bo, Clohisey, Sara M., Chia, Bing Shao, Wang, Bo, Cui, Ang, Eisenhaure, Thomas, Schweitzer, Lawrence D., Hoover, Paul, Parkinson, Nicholas J., Nachshon, Aharon, Smith, Nikki, Regan, Tim, Farr, David, Gutmann, Michael U., Bukhari, Syed Irfan, Law, Andrew, Sangesland, Maya, Gat-Viks, Irit, Digard, Paul, Vasudevan, Shobha, Lingwood, Daniel, Dockrell, David H., Doench, John G., Baillie, J. Kenneth, Hacohen, Nir
Publicado 2020

A large peptidome dataset improves HLA class I epitope prediction across most of the human population

por Sarkizova, Siranush, Klaeger, Susan, Le, Phuong M., Li, Letitia W., Oliveira, Giacomo, Keshishian, Hasmik, Hartigan, Christina R., Zhang, Wandi, Braun, David A., Ligon, Keith L., Bachireddy, Pavan, Zervantonakis, Ioannis K., Rosenbluth, Jennifer M., Ouspenskaia, Tamara, Law, Travis, Justesen, Sune, Stevens, Jonathan, Lane, William J., Eisenhaure, Thomas, Zhang, Guang Lan, Clauser, Karl R., Hacohen, Nir, Carr, Steven A., Wu, Catherine J., Keskin, Derin B.
Publicado 2019

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

por Tonnerre, Pierre, Wolski, David, Subudhi, Sonu, Al-Jabban, Jihad, Hoogeveen, Ruben C., Damasio, Marcos, Drescher, Hannah K., Bartsch, Lea M., Tully, Damien C., Sen, Debattama R., Bean, David J., Brown, Joelle, Torres-Cornejo, Almudena, Robidoux, Maxwell, Kvistad, Daniel, Alatrakchi, Nadia, Cui, Ang, Lieb, David, Cheney, James A., Gustafson, Jenna, Lewis-Ximenez, Lia L, Massenet-Regad, Lucile, Eisenhaure, Thomas, Aneja, Jasneet, Haining, W. Nicholas, Chung, Raymond T., Hacohen, Nir, Allen, Todd M., Kim, Arthur Y., Lauer, Georg M.
Publicado 2021

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue

por Donlin, Laura T., Rao, Deepak A., Wei, Kevin, Slowikowski, Kamil, McGeachy, Mandy J., Turner, Jason D., Meednu, Nida, Mizoguchi, Fumitaka, Gutierrez-Arcelus, Maria, Lieb, David J., Keegan, Joshua, Muskat, Kaylin, Hillman, Joshua, Rozo, Cristina, Ricker, Edd, Eisenhaure, Thomas M., Li, Shuqiang, Browne, Edward P., Chicoine, Adam, Sutherby, Danielle, Noma, Akiko, Nusbaum, Chad, Kelly, Stephen, Pernis, Alessandra B., Ivashkiv, Lionel B., Goodman, Susan M., Robinson, William H., Utz, Paul J., Lederer, James A., Gravallese, Ellen M., Boyce, Brendan F., Hacohen, Nir, Pitzalis, Costantino, Gregersen, Peter K., Firestein, Gary S., Raychaudhuri, Soumya, Moreland, Larry W., Holers, V. Michael, Bykerk, Vivian P., Filer, Andrew, Boyle, David L., Brenner, Michael B., Anolik, Jennifer H.
Publicado 2018

The immune cell landscape in kidneys of patients with lupus nephritis

por Arazi, Arnon, Rao, Deepak A., Berthier, Celine C., Davidson, Anne, Liu, Yanyan, Hoover, Paul J., Chicoine, Adam, Eisenhaure, Thomas M., Jonsson, A. Helena, Li, Shuqiang, Lieb, David J., Zhang, Fan, Slowikowski, Kamil, Browne, Edward P., Noma, Akiko, Sutherby, Danielle, Steelman, Scott, Smilek, Dawn E., Tosta, Patti, Apruzzese, William, Massarotti, Elena, Dall’Era, Maria, Park, Meyeon, Kamen, Diane L., Furie, Richard A., Payan-Schober, Fernanda, Pendergraft, William F., McInnis, Elizabeth A., Buyon, Jill P., Petri, Michelle A., Putterman, Chaim, Kalunian, Kenneth C., Woodle, E. Steve, Lederer, James A., Hildeman, David A., Nusbaum, Chad, Raychaudhuri, Soumya, Kretzler, Matthias, Anolik, Jennifer H., Brenner, Michael B., Wofsy, David, Hacohen, Nir, Diamond, Betty
Publicado 2019

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

por Zhang, Fan, Wei, Kevin, Slowikowski, Kamil, Fonseka, Chamith Y., Rao, Deepak A., Kelly, Stephen, Goodman, Susan M., Tabechian, Darren, Hughes, Laura B., Salomon-Escoto, Karen, Watts, Gerald F. M., Jonsson, Anna H., Rangel-Moreno, Javier, Pellett, Nida M., Rozo, Cristina, Apruzzese, William, Eisenhaure, Thomas M., Lieb, David J., Boyle, David L., Mandelin, Arthur M., Boyce, Brendan F., DiCarlo, Edward, Gravallese, Ellen M., Gregersen, Peter K., Moreland, Larry, Firestein, Gary S., Hacohen, Nir, Nusbaum, Chad, Lederer, James A., Perlman, Harris, Pitzalis, Costantino, Filer, Andrew, Holers, V. Michael, Bykerk, Vivian P., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya, Albrecht, Jennifer, Bridges, S. Louis, Buckley, Christopher D., Buckner, Jane H., Dolan, James, Guthridge, Joel M., Gutierrez-Arcelus, Maria, Ivashkiv, Lionel B., James, Eddie A., James, Judith A., Keegan, Josh, Lee, Yvonne C., McGeachy, Mandy J., McNamara, Michael A., Mears, Joseph R., Mizoguchi, Fumitaka, Nguyen, Jennifer P., Noma, Akiko, Orange, Dana E., Rohani-Pichavant, Mina, Ritchlin, Christopher, Robinson, William H., Seshadri, Anupamaa, Sutherby, Danielle, Seifert, Jennifer, Turner, Jason D., Utz, Paul J.
Publicado 2019