The Inhibitory Potential of 2′-dihalo Ribonucleotides against HCV: Molecular Docking, Molecular Simulations, MM-BPSA, and DFT Studies

por Khalil, Ahmed, El-Khouly, Amany S., Elkaeed, Eslam B., Eissa, Ibrahim H.
Publicado 2022

Design, eco-friendly synthesis, molecular modeling and anticancer evaluation of thiazol-5(4H)-ones as potential tubulin polymerization inhibitors targeting the colchicine binding s...

por El-Naggar, Abeer M., Eissa, Ibrahim H., Belal, Amany, El-Sayed, Amira A.
Publicado 2020

In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT S...

por Alesawy, Mohamed S., Elkaeed, Eslam B., Alsfouk, Aisha A., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2021

Discovery of Potential SARS-CoV-2 Papain-like Protease Natural Inhibitors Employing a Multi-Phase In Silico Approach

por Elkaeed, Eslam B., Metwaly, Ahmed M., Alesawy, Mohamed S., Saleh, Abdulrahman M., Alsfouk, Aisha A., Eissa, Ibrahim H.
Publicado 2022

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10

por Eissa, Ibrahim H., Khalifa, Mohamed M., Elkaeed, Eslam B., Hafez, Elsayed E., Alsfouk, Aisha A., Metwaly, Ahmed M.
Publicado 2021

The Computational Preventive Potential of the Rare Flavonoid, Patuletin, Isolated from Tagetes patula, against SARS-CoV-2

por Metwaly, Ahmed M., Elkaeed, Eslam B., Alsfouk, Bshra A., Saleh, Abdulrahman M., Mostafa, Ahmad E., Eissa, Ibrahim H.
Publicado 2022

Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation

por Hagras, Mohamed, El Deeb, Moshira A., Elzahabi, Heba S. A., Elkaeed, Eslam B., Mehany, Ahmed B. M., Eissa, Ibrahim H.
Publicado 2021

Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apopto...

por Saleh, Abdulrahman M., Mahdy, Hazem A., El-Zahabi, Mohamed Ayman, Mehany, Ahmed B. M., Khalifa, Mohamed M., Eissa, Ibrahim H.
Publicado 2023

Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents

por Kotb, Anas Ramadan, Bakhotmah, Dina A., Abdallah, Abdallah E., Elkady, Hazem, Taghour, Mohammed S., Eissa, Ibrahim. H., El-Zahabi, Mohamed Ayman
Publicado 2022

Design, synthesis, docking, MD simulations, and anti-proliferative evaluation of thieno[2,3-d]pyrimidine derivatives as new EGFR inhibitors

por Sobh, Eman A., Dahab, Mohammed A., Elkaeed, Eslam B., Alsfouk, Aisha A., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2023

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor

por Al-Karmalawy, Ahmed A., Dahab, Mohammed A., Metwaly, Ahmed M., Elhady, Sameh S., Elkaeed, Eslam B., Eissa, Ibrahim H., Darwish, Khaled M.
Publicado 2021

Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies

por Ma, Chao, Taghour, Mohammed S., Belal, Amany, Mehany, Ahmed B. M., Mostafa, Naglaa, Nabeeh, Ahmed, Eissa, Ibrahim H., Al-Karmalawy, Ahmed A.
Publicado 2021

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies

por Khalifa, Mohamed M., Al-Karmalawy, Ahmed A., Elkaeed, Eslam B., Nafie, Mohamed S., Tantawy, Mohamed A., Eissa, Ibrahim H., Mahdy, Hazem A.
Publicado 2021

A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease

por Elkaeed, Eslam B., Eissa, Ibrahim H., Elkady, Hazem, Abdelalim, Ahmed, Alqaisi, Ahmad M., Alsfouk, Aisha A., Elwan, Alaa, Metwaly, Ahmed M.
Publicado 2022

Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

por Kotb, Anas Ramadan, Abdallah, Abdallah E., Elkady, Hazem, Eissa, Ibrahim H., Taghour, Mohammed S., Bakhotmah, Dina Abed, Abdelghany, Tamer M., El-Zahabi, Mohamed Ayman
Publicado 2023

Traditional ancient Egyptian medicine: A review

por Metwaly, Ahmed M., Ghoneim, Mohammed M., Eissa, Ibrahim.H., Elsehemy, Islam A., Mostafa, Ahmad E., Hegazy, Mostafa M., Afifi, Wael M., Dou, Deqiang
Publicado 2021

Ligand and Structure-Based In Silico Determination of the Most Promising SARS-CoV-2 nsp16-nsp10 2′-o-Methyltransferase Complex Inhibitors among 3009 FDA Approved Drugs

por Eissa, Ibrahim H., Alesawy, Mohamed S., Saleh, Abdulrahman M., Elkaeed, Eslam B., Alsfouk, Bshra A., El-Attar, Abdul-Aziz M. M., Metwaly, Ahmed M.
Publicado 2022

New Anticancer Theobromine Derivative Targeting EGFR(WT) and EGFR(T790M): Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies

por Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Alsfouk, Aisha A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers

por Alanazi, Mohammed M., Eissa, Ibrahim H., Alsaif, Nawaf A., Obaidullah, Ahmad J., Alanazi, Wael A., Alasmari, Abdullah F., Albassam, Hussam, Elkady, Hazem, Elwan, Alaa
Publicado 2021

Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR...

por Eissa, Ibrahim H., El-Haggar, Radwan, Dahab, Mohammed A., Ahmed, Marwa F., Mahdy, Hazem A., Alsantali, Reem I., Elwan, Alaa, Masurier, Nicolas, Fatahala, Samar S.
Publicado 2022