ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes

por Brozzi, Flora, Eizirik, Décio L.
Publicado 2016

On the Immense Variety and Complexity of Circumstances Conditioning Pancreatic β-Cell Apoptosis in Type 1 Diabetes

por Eizirik, Decio L., Grieco, Fabio A.
Publicado 2012

Checks and Balances—The Limits of β-Cell Endurance to ER Stress

por Eizirik, Decio L., Coomans de Brachène, Alexandra
Publicado 2017

In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells

por Naamane, Najib, van Helden, Jacques, Eizirik, Decio L
Publicado 2007

Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes

por Colli, Maikel L., Szymczak, Florian, Eizirik, Decio L.
Publicado 2020

From Pancreatic β-Cell Gene Networks to Novel Therapies for Type 1 Diabetes

por Eizirik, Decio L., Szymczak, Florian, Alvelos, Maria Inês, Martin, Frank
Publicado 2021

Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways

por Bosi, Emanuele, Marchetti, Piero, Rutter, Guy Allen, Eizirik, Decio Laks
Publicado 2022

Clic4, a novel protein that sensitizes β-cells to apoptosis()

por Patel, Dhaval, Ythier, Damien, Brozzi, Flora, Eizirik, Decio L., Thorens, Bernard
Publicado 2015

Beta Cell Imaging—From Pre-Clinical Validation to First in Man Testing

por Demine, Stephane, Schulte, Michael L., Territo, Paul R., Eizirik, Decio L.
Publicado 2020

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

por Gurzov, Esteban N., Ortis, Fernanda, Bakiri, Latifa, Wagner, Erwin F., Eizirik, Decio L.
Publicado 2008

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

por Colli, Maikel L., Moore, Fabrice, Gurzov, Esteban N., Ortis, Fernanda, Eizirik, Decio L.
Publicado 2010

MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity

por Tyka, Karolina, Jörns, Anne, Turatsinze, Jean-Valery, Eizirik, Decio L., Lenzen, Sigurd, Gurgul-Convey, Ewa
Publicado 2019

Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells

por Demine, Stéphane, Schiavo, Andrea Alex, Marín-Cañas, Sandra, Marchetti, Piero, Cnop, Miriam, Eizirik, Decio L.
Publicado 2020

The Pancreatic ß-cell Response to Secretory Demands and Adaption to Stress

por Kalwat, Michael A, Scheuner, Donalyn, Rodrigues-dos-Santos, Karina, Eizirik, Decio L, Cobb, Melanie H
Publicado 2021

BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis

por Perez-Serna, Atenea A., Dos Santos, Reinaldo S., Ripoll, Cristina, Nadal, Angel, Eizirik, Decio L., Marroqui, Laura
Publicado 2023

Endogenous mitochondrial double‐stranded RNA is not an activator of the type I interferon response in human pancreatic beta cells

por Coomans de Brachène, Alexandra, Castela, Angela, Musuaya, Anyïshai E., Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L.
Publicado 2021

Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis

por Magnusson, Nils E, Cardozo, Alessandra K, Kruhøffer, Mogens, Eizirik, Decio L, Ørntoft, Torben F, Jensen, Jens L
Publicado 2005

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim

por Santin, Izortze, Moore, Fabrice, Colli, Maikel L., Gurzov, Esteban N., Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L.
Publicado 2011

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells

por Moore, Fabrice, Santin, Izortze, Nogueira, Tatiane C., Gurzov, Esteban N., Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L.
Publicado 2012

Tolerogenic insulin peptide therapy precipitates type 1 diabetes

por Bergman, Marie-Louise, Lopes-Carvalho, Thiago, Martins, Ana-Catarina, Grieco, Fabio A., Eizirik, Décio L., Demengeot, Jocelyne
Publicado 2017