Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehensive computational investigations

por Ejaz, Syeda Abida, Aziz, Mubashir, Zafar, Zeenat, Akhtar, Naveed, Ogaly, Hanan A.
Publicado 2023

Pharmacophore-Based Virtual Screening and In-Silico Explorations of Biomolecules (Curcumin Derivatives) of Curcuma longa as Potential Lead Inhibitors of ERBB and VEGFR-2 for the Tr...

por Ejaz, Syeda Abida, Aziz, Mubashir, Fawzy Ramadan, Mohamed, Fayyaz, Ammara, Bilal, Muhammad Sajjad
Publicado 2023

Synthesis, Biological Evaluation, and Molecular Dynamics of Carbothioamides Derivatives as Carbonic Anhydrase II and 15-Lipoxygenase Inhibitors

por Channar, Pervaiz Ali, Alharthy, Rima D., Ejaz, Syeda Abida, Saeed, Aamer, Iqbal, Jamshed
Publicado 2022

Hypothyroidism correlates with dyslipidemia and protein contents in patients with various metabolic disorders

por Kiran, Muniba, Ejaz, Samina, Iqbal, Muhamad Nouman, Malik, Waqas Nazir, Zahoor, Sana, Ejaz, Syeda Abida
Publicado 2022

Synthesis of Brominated 2-Phenitidine Derivatives as Valuable Inhibitors of Cholinesterases for the Treatment of Alzheimer’s Disease

por Abbasi, Muhammad Athar, Saeed, Amna, Aziz-ur-Rehman, Mohmmed Khan, Khalid, Ashraf, Muhammad, Ejaz, Syeda Abida
Publicado 2014

Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies

por Iqbal, Jamshed, El-Gamal, Mohammed I., Ejaz, Syeda Abida, Lecka, Joanna, Sévigny, Jean, Oh, Chang-Hyun
Publicado 2018

Synthesis, characterization and biological evaluation of pyrazole-based benzene sulfonamides as inhibitors of human carbonic anhydrase II, IX and XII

por Hussain, Tajamul, Ullah, Saif, Alrokayan, Salman, Alamery, Salman, Mohammed, Arif Ahmed, Ejaz, Syeda Abida, Aziz, Mubashir, Iqbal, Jamshed
Publicado 2023

[1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase

por Alrokayan, Salman, Hussain, Tajamul, Alamery, Salman, Mohammed, Arif Ahmed, Mahmood, Abid, Ejaz, Syeda Abida, Langer, Peter, Iqbal, Jamshed
Publicado 2023

Identification of potent inhibitors of NEK7 protein using a comprehensive computational approach

por Aziz, Mubashir, Ejaz, Syeda Abida, Tamam, Nissren, Siddique, Farhan, Riaz, Naheed, Qais, Faizan Abul, Chtita, Samir, Iqbal, Jamshed
Publicado 2022

Discovery of Phenylcarbamoylazinane-1,2,4-Triazole Amides Derivatives as the Potential Inhibitors of Aldo-Keto Reductases (AKR1B1 & AKRB10): Potential Lead Molecules for Treatment...

por Saeed, Amna, Ejaz, Syeda Abida, Sarfraz, Muhammad, Tamam, Nissren, Siddique, Farhan, Riaz, Naheed, Qais, Faizan Abul, Chtita, Samir, Iqbal, Jamshed
Publicado 2022

Structure and surface analyses of a newly synthesized acyl thiourea derivative along with its in silico and in vitro investigations for RNR, DNA binding, urease inhibition and radi...

por Khalid, Aqsa, Arshad, Nasima, Channar, Pervaiz Ali, Saeed, Aamer, Mir, Muhammad Ismail, Abbas, Qamar, Ejaz, Syeda Abida, Hökelek, Tuncer, Saeed, Amna, Tehzeeb, Arfa
Publicado 2022

Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies

por Ahmed, Atteeque, Saeed, Aamer, Ejaz, Syeda Abida, Aziz, Mubashir, Hashmi, Muhammad Zaffar, Channar, Pervaiz Ali, Abbas, Qamar, Raza, Hussain, Shafiq, Zahid, El-Seedi, Hesham R.
Publicado 2022

Synthesis, DFT and molecular docking of novel (Z)-4-bromo-N-(4-butyl-3 (quinolin-3-yl)thiazol-2(3H)-ylidene)benzamide as elastase inhibitor

por Mustafa, Muhammad Naeem, Channar, Pervaiz Ali, Ejaz, Syeda Abida, Afzal, Saira, Aziz, Mubashir, Shamim, Tahira, Saeed, Aamer, Alsfouk, Aisha A., Ujan, Rabail, Abbas, Qamar, Hökelek, Tuncer
Publicado 2023

Deep Learning and Structure-Based Virtual Screening for Drug Discovery against NEK7: A Novel Target for the Treatment of Cancer

por Aziz, Mubashir, Ejaz, Syeda Abida, Zargar, Seema, Akhtar, Naveed, Aborode, Abdullahi Tunde, A. Wani, Tanveer, Batiha, Gaber El-Saber, Siddique, Farhan, Alqarni, Mohammed, Akintola, Ashraf Akintayo
Publicado 2022

Design, Synthesis, Kinetic Analysis and Pharmacophore-Directed Discovery of 3-Ethylaniline Hybrid Imino-Thiazolidinone as Potential Inhibitor of Carbonic Anhydrase II: An Emerging...

por Ahmed, Atteeque, Aziz, Mubashir, Ejaz, Syeda Abida, Channar, Pervaiz Ali, Saeed, Aamer, Zargar, Seema, Wani, Tanveer A., Hamad, Asad, Abbas, Qamar, Raza, Hussain, Kim, Song Ja
Publicado 2022

In-silico Investigations of quinine and quinidine as potential Inhibitors of AKR1B1 and AKR1B10: Functional and structural characterization

por Ejaz, Syeda Abida, Saeed, Amna, Birmani, Pervez Rashid, Katubi, Khadijah Mohammedsalaeh, Elqahtani, Zainab Mufarreh, Al-Buriahi, M. S., Ujan, Rabail, Siddique, Farhan, Ahmed, Samia ben, Alrowaili, Z. A.
Publicado 2022

Computational Investigation of 1, 3, 4 Oxadiazole Derivatives as Lead Inhibitors of VEGFR 2 in Comparison with EGFR: Density Functional Theory, Molecular Docking and Molecular Dyna...

por Bilal, Muhammad Sajjad, Ejaz, Syeda Abida, Zargar, Seema, Akhtar, Naveed, Wani, Tanveer A., Riaz, Naheed, Aborode, Adullahi Tunde, Siddique, Farhan, Altwaijry, Nojood, Alkahtani, Hamad M., Umar, Haruna Isiyaku
Publicado 2022

Synthesis, kinetic studies and in-silico investigations of novel quinolinyl-iminothiazolines as alkaline phosphatase inhibitors

por Mustafa, Muhammad Naeem, Channar, Pervaiz Ali, Sarfraz, Muhammad, Saeed, Aamer, Ejaz, Syeda Abida, Aziz, Mubashir, Alasmary, Fatmah Ali, Alsoqair, Hanadi Yaqob, Raza, Hussain, Kim, Song Ja, Hamad, Asad
Publicado 2023

Synthesis and Evaluation of Novel S-alkyl Phthalimide- and S-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase

por Khan, Bilal Ahmad, Hamdani, Syeda Shamila, Jalil, Saquib, Ejaz, Syeda Abida, Iqbal, Jamshed, Shawky, Ahmed M., Alqahtani, Alaa M., Gabr, Gamal A., Ibrahim, Mahmoud A. A., Sidhom, Peter A.
Publicado 2022

Design, synthesis, biochemical and in silico characterization of novel naphthalene-thiourea conjugates as potential and selective inhibitors of alkaline phosphatase

por Saeed, Aamer, Ashraf, Saba, Aziz, Mubashir, Channar, Pervaiz Ali, Ejaz, Syeda Abida, Fayyaz, Ammara, Abbas, Qamar, Alasmary, Fatmah Ali, Karami, Abdulnasser Mahmoud, Tehzeeb, Arfa, Mumtaz, Amara, El-Seedi, Hesham R.
Publicado 2023