Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers

por Brown, Lauren M., Ekert, Paul G., Fleuren, Emmy D. G.
Publicado 2023

A novel Apaf-1–independent putative caspase-2 activation complex

por Read, Stuart H., Baliga, Belinda C., Ekert, Paul G., Vaux, David L., Kumar, Sharad
Publicado 2002

Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9

por Ekert, Paul G., Silke, John, Hawkins, Christine J., Verhagen, Anne M., Vaux, David L.
Publicado 2001

MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data

por Cmero, Marek, Schmidt, Breon, Majewski, Ian J., Ekert, Paul G., Oshlack, Alicia, Davidson, Nadia M.
Publicado 2021

Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9

por Marsden, Vanessa S., Ekert, Paul G., Van Delft, Mark, Vaux, David L., Adams, Jerry M., Strasser, Andreas
Publicado 2004

JAFFAL: detecting fusion genes with long-read transcriptome sequencing

por Davidson, Nadia M., Chen, Ying, Sadras, Teresa, Ryland, Georgina L., Blombery, Piers, Ekert, Paul G., Göke, Jonathan, Oshlack, Alicia
Publicado 2022

p53-Dependent Transcriptional Responses to Interleukin-3 Signaling

por Jabbour, Anissa M., Gordon, Lavinia, Daunt, Carmel P., Green, Benjamin D., Kok, Chung H., D'Andrea, Richard, Ekert, Paul G.
Publicado 2012

Clinker: visualizing fusion genes detected in RNA-seq data

por Schmidt, Breon M, Davidson, Nadia M, Hawkins, Anthony D K, Bartolo, Ray, Majewski, Ian J, Ekert, Paul G, Oshlack, Alicia
Publicado 2018

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites

por Silke, John, Hawkins, Christine J., Ekert, Paul G., Chew, Joanne, Day, Catherine L., Pakusch, Miha, Verhagen, Anne M., Vaux, David L.
Publicado 2002

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

por Ekert, Paul G., Read, Stuart H., Silke, John, Marsden, Vanessa S., Kaufmann, Hitto, Hawkins, Christine J., Gerl, Robert, Kumar, Sharad, Vaux, David L.
Publicado 2004

Enhancing the Potential of Immunotherapy in Paediatric Sarcomas: Breaking the Immunosuppressive Barrier with Receptor Tyrosine Kinase Inhibitors

por Fleuren, Emmy D. G., Terry, Rachael L., Meyran, Deborah, Omer, Natacha, Trapani, Joseph A., Haber, Michelle, Neeson, Paul J., Ekert, Paul G.
Publicado 2021

Advances in CAR T cell immunotherapy for paediatric brain tumours

por Rao, Padmashree, Furst, Liam, Meyran, Deborah, Mayoh, Chelsea, Neeson, Paul J., Terry, Rachael, Khuong-Quang, Dong-Anh, Mantamadiotis, Theo, Ekert, Paul G.
Publicado 2022

Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis

por Manoharan, Neevika, Ajuyah, Pamela, Senapati, Akanksha, Wong, Marie, Mullins, Anna, Rodriguez, Michael, Doyle, Helen, McCowage, Geoff, Lau, Loretta M. S., Ekert, Paul G., Ziegler, David S.
Publicado 2021

The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice

por Pardo, Julian, Urban, Christin, Galvez, Eva M., Ekert, Paul G., Müller, Uwe, Kwon-Chung, June, Lobigs, Mario, Müllbacher, Arno, Wallich, Reinhard, Borner, Christoph, Simon, Markus M.
Publicado 2006

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis

por Wensveen, Felix M., Geest, Christian R., Libregts, Sten F. W. M., Derks, Ingrid A. M., Ekert, Paul G., Labi, Verena, Villunger, Andreas, Nolte, Martijn A., Eldering, Eric
Publicado 2013

Imprinted CDKN1C Is a Tumor Suppressor in Rhabdoid Tumor and Activated by Restoration of SMARCB1 and Histone Deacetylase Inhibitors

por Algar, Elizabeth M., Muscat, Andrea, Dagar, Vinod, Rickert, Christian, Chow, C. W., Biegel, Jaclyn A., Ekert, Paul G., Saffery, Richard, Craig, Jeff, Johnstone, Ricky W., Ashley, David M.
Publicado 2009

Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins

por Goodall, Katharine J., Finch-Edmondson, Megan L., van Vuuren, Joanne, Yeoh, George C., Gentle, Ian E., Vince, James E., Ekert, Paul G., Vaux, David L., Callus, Bernard A.
Publicado 2016

The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts

por Bandopadhayay, Pratiti, Jabbour, Anissa M, Riffkin, Christopher, Salmanidis, Marika, Gordon, Lavinia, Popovski, Dean, Rigby, Lin, Ashley, David M, Watkins, David N, Thomas, David M, Algar, Elizabeth, Ekert, Paul G
Publicado 2013

ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia

por Schmidt, Breon, Brown, Lauren M., Ryland, Georgina L., Lonsdale, Andrew, Kosasih, Hansen J., Ludlow, Louise E., Majewski, Ian J., Blombery, Piers, Ekert, Paul G., Davidson, Nadia M., Oshlack, Alicia
Publicado 2022

Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma

por Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J., Ekert, Paul G.
Publicado 2021