Energetics of the Microsporidian Polar Tube Invasion Machinery

por Chang, Ray, Davydov, Ari, Jaroenlak, Pattana, Budaitis, Breane, Ekiert, Damian C., Bhabha, Gira, Prakash, Manu
Publicado 2023

Phospholipid transport to the bacterial outer membrane through an envelope-spanning bridge

por Cooper, Benjamin F., Clark, Robert, Kudhail, Anju, Bhabha, Gira, Ekiert, Damian C., Khalid, Syma, Isom, Georgia L.
Publicado 2023

Structure of bacterial phospholipid transporter MlaFEDB with substrate bound

por Coudray, Nicolas, Isom, Georgia L, MacRae, Mark R, Saiduddin, Mariyah N, Bhabha, Gira, Ekiert, Damian C
Publicado 2020

An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody

por Krause, Jens C., Ekiert, Damian C., Tumpey, Terrence M., Smith, Patricia B., Wilson, Ian A., Crowe, James E.
Publicado 2011

3-Dimensional organization and dynamics of the microsporidian polar tube invasion machinery

por Jaroenlak, Pattana, Cammer, Michael, Davydov, Alina, Sall, Joseph, Usmani, Mahrukh, Liang, Feng-Xia, Ekiert, Damian C., Bhabha, Gira
Publicado 2020

Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses

por Tsibane, Tshidi, Ekiert, Damian C., Krause, Jens C., Martinez, Osvaldo, Crowe, James E., Wilson, Ian A., Basler, Christopher F.
Publicado 2012

A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans

por Gang, Spencer S., Grover, Manish, Reddy, Kirthi C., Raman, Deevya, Chang, Ya-Ting, Ekiert, Damian C., Barkoulas, Michalis, Troemel, Emily R.
Publicado 2022

De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters

por Liu, Yu, Zhang, Xin, Tan, Yun Lei, Bhabha, Gira, Ekiert, Damian C., Kipnis, Yakov, Bjelic, Sinisa, Baker, David, Kelly, Jeffery W.
Publicado 2014

Protein–protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning

por MacRae, Mark R., Puvanendran, Dhenesh, Haase, Max A.B., Coudray, Nicolas, Kolich, Ljuvica, Lam, Cherry, Baek, Minkyung, Bhabha, Gira, Ekiert, Damian C.
Publicado 2023

Exploring the repeat protein universe through computational protein design

por Brunette, TJ, Parmeggiani, Fabio, Huang, Po-Ssu, Bhabha, Gira, Ekiert, Damian C., Tsutakawa, Susan E., Hura, Greg L., Tainer, John A., Baker, David
Publicado 2015

3D reconstructions of parasite development and the intracellular niche of the microsporidian pathogen Encephalitozoon intestinalis

por Antao, Noelle V., Lam, Cherry, Davydov, Ari, Riggi, Margot, Sall, Joseph, Petzold, Christopher, Liang, Feng-Xia, Iwasa, Janet H., Ekiert, Damian C., Bhabha, Gira
Publicado 2023

Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization

por Ilmain, Juliana K., Perelman, Sofya S., Panepinto, Maria C., Irnov, Irnov, Coudray, Nicolas, Samhadaneh, Nora, Pironti, Alejandro, Ueberheide, Beatrix, Ekiert, Damian C., Bhabha, Gira, Torres, Victor J.
Publicado 2023

Divergent evolution of protein conformational dynamics in dihydrofolate reductase

por Bhabha, Gira, Ekiert, Damian C., Jennewein, Madeleine, Zmasek, Christian M., Tuttle, Lisa M., Kroon, Gerard, Dyson, H. Jane, Godzik, Adam, Wilson, Ian A., Wright, Peter E.
Publicado 2013

Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation

por Kolich, Ljuvica R, Chang, Ya-Ting, Coudray, Nicolas, Giacometti, Sabrina I, MacRae, Mark R, Isom, Georgia L, Teran, Evelyn M, Bhabha, Gira, Ekiert, Damian C
Publicado 2020

High-throughput small molecule screen identifies inhibitors of microsporidia invasion and proliferation in C. elegans

por Murareanu, Brandon M., Antao, Noelle V., Zhao, Winnie, Dubuffet, Aurore, El Alaoui, Hicham, Knox, Jessica, Ekiert, Damian C., Bhabha, Gira, Roy, Peter J., Reinke, Aaron W.
Publicado 2022

De novo design of obligate ABC-type heterotrimeric proteins

por Bermeo, Sherry, Favor, Andrew, Chang, Ya-Ting, Norris, Andrew, Boyken, Scott E., Hsia, Yang, Haddox, Hugh K., Xu, Chunfu, Brunette, T. J., Wysocki, Vicki H., Bhabha, Gira, Ekiert, Damian C., Baker, David
Publicado 2022

Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis

por Fichtner, Miriam L., Vieni, Casey, Redler, Rachel L., Kolich, Ljuvica, Jiang, Ruoyi, Takata, Kazushiro, Stathopoulos, Panos, Suarez, Pablo A., Nowak, Richard J., Burden, Steven J., Ekiert, Damian C., O’Connor, Kevin C.
Publicado 2020

De novo design of modular peptide-binding proteins by superhelical matching

por Wu, Kejia, Bai, Hua, Chang, Ya-Ting, Redler, Rachel, McNally, Kerrie E., Sheffler, William, Brunette, T. J., Hicks, Derrick R., Morgan, Tomos E., Stevens, Tim J., Broerman, Adam, Goreshnik, Inna, DeWitt, Michelle, Chow, Cameron M., Shen, Yihang, Stewart, Lance, Derivery, Emmanuel, Silva, Daniel Adriano, Bhabha, Gira, Ekiert, Damian C., Baker, David
Publicado 2023

Genetic variation of staphylococcal LukAB toxin determines receptor tropism

por Perelman, Sofya S., James, David B.A., Boguslawski, Kristina M., Nelson, Chase W., Ilmain, Juliana K., Zwack, Erin E., Prescott, Rachel A., Mohamed, Adil, Tam, Kayan, Chan, Rita, Narechania, Apurva, Pawline, Miranda B., Vozhilla, Nikollaq, Moustafa, Ahmed M., Kim, Sang Y., Dittmann, Meike, Ekiert, Damian C., Bhabha, Gira, Shopsin, Bo, Planet, Paul J., Koralov, Sergei B., Torres, Victor J.
Publicado 2021

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

por Edman, Natasha I, Redler, Rachel L, Phal, Ashish, Schlichthaerle, Thomas, Srivatsan, Sanjay R, Etemadi, Ali, An, Seong J, Favor, Andrew, Ehnes, Devon, Li, Zhe, Praetorius, Florian, Gordon, Max, Yang, Wei, Coventry, Brian, Hicks, Derrick R., Cao, Longxing, Bethel, Neville, Heine, Piper, Murray, Analisa, Gerben, Stacey, Carter, Lauren, Miranda, Marcos, Negahdari, Babak, Lee, Sangwon, Trapnell, Cole, Stewart, Lance, Ekiert, Damian C., Schlessinger, Joseph, Shendure, Jay, Bhabha, Gira, Ruohola-Baker, Hannele, Baker, David
Publicado 2023