VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases

por Ekstrom, Thomas L., Pathoulas, Nicholas M., Huehls, Amelia M., Kanakkanthara, Arun, Karnitz, Larry M.
Publicado 2021

Robust activation of microhomology-mediated end joining for precision gene editing applications

por Ata, Hirotaka, Ekstrom, Thomas L., Martínez-Gálvez, Gabriel, Mann, Carla M., Dvornikov, Alexey V., Schaefbauer, Kyle J., Ma, Alvin C., Dobbs, Drena, Clark, Karl J., Ekker, Stephen C.
Publicado 2018

Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma

por Kanakkanthara, Arun, Hou, Xiaonan, Ekstrom, Thomas L., Zanfagnin, Valentina, Huehls, Amelia M., Kelly, Rebecca L., Ding, Husheng, Larson, Melissa C., Vasmatzis, George, Oberg, Ann L., Kaufmann, Scott H., Mansfield, Aaron S., Weroha, S. John, Karnitz, Larry M.
Publicado 2022