Molecular modelling insights into a physiologically favourable approach to eicosanoid biosynthesis inhibition through novel thieno[2,3-b]pyridine derivatives

por Mohamed, Mosaad S., Mansour, Yara E., Amin, Hatem K., El-Araby, Moustafa E.
Publicado 2018

Assessments of Alpha-Amylase Inhibitory Potential of Tagetes Flavonoids through In Vitro, Molecular Docking, and Molecular Dynamics Simulation Studies

por Mohamed, Gamal A., Omar, Abdelsattar M., El-Araby, Moustafa E., Mass, Shaza, Ibrahim, Sabrin R. M.
Publicado 2023

Molecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on Paclitaxel

por El-Araby, Moustafa E., Omar, Abdelsattar M., Khayat, Maan T., Assiri, Hanan A., Al-Abd, Ahmed M.
Publicado 2017

An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling

por Omar, Abdelsattar M., Abdulmalik, Osheiza, Ghatge, Mohini S., Muhammad, Yosra A., Paredes, Steven D., El-Araby, Moustafa E., Safo, Martin K.
Publicado 2020

New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase

por Alasmary, Fatmah A. S., Alnahdi, Fatima S., Ben Bacha, Abir, El-Araby, Amr M., Moubayed, Nadine, Alafeefy, Ahmed M., El-Araby, Moustafa E.
Publicado 2017

Synthetic bulky NS4A peptide variants bind to and inhibit HCV NS3 protease

por El-Araby, Moustafa E., Omar, Abdelsattar M., Soror, Sameh H., Arold, Stefan T., Khayat, Maan T., Asfour, Hani Z., Bamane, Faida, Elfaky, Mahmoud A.
Publicado 2020

Bioassay Guided Isolation and Docking Studies of a Potential β-Lactamase Inhibitor from Clutia myricoides

por Elfaky, Mahmoud A., El-Halawany, Ali M., Koshak, Abdulrahman E., Alshali, Khalid Z., El-Araby, Moustafa E., Khayat, Maan T., Abdallah, Hossam M.
Publicado 2020

1H-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease

por Omar, Abdelsattar M., Elfaky, Mahmoud A., Arold, Stefan T., Soror, Sameh H., Khayat, Maan T., Asfour, Hani Z., Bamane, Faida H., El-Araby, Moustafa E.
Publicado 2020

Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin

por Omar, Abdelsattar M., Mahran, Mona A., Ghatge, Mohini S., Bamane, Faida H. A., Ahmed, Mostafa H., El-Araby, Moustafa E., Abdulmalik, Osheiza, Safo, Martin K.
Publicado 2016

Insights on Cancer Cell Inhibition, Subcellular Activities, and Kinase Profile of Phenylacetamides Pending 1H-Imidazol-5-One Variants

por Khayat, Maan T., Omar, Abdelsattar M., Ahmed, Farid, Khan, Mohammad I., Ibrahim, Sara M., Muhammad, Yosra A., Malebari, Azizah M., Neamatallah, Thikryat, El-Araby, Moustafa E.
Publicado 2022

SAR Probing of KX2-391 Provided Analogues With Juxtaposed Activity Profile Against Major Oncogenic Kinases

por Omar, Abdelsattar M., Khayat, Maan T., Ahmed, Farid, Muhammad, Yosra A., Malebari, Azizah M., Ibrahim, Sara M., Khan, Mohammad I., Shah, Dhaval K., Childers, Wayne E., El-Araby, Moustafa E.
Publicado 2022

Improving the Solubility and Oral Bioavailability of a Novel Aromatic Aldehyde Antisickling Agent (PP10) for the Treatment of Sickle Cell Disease

por Ahmed, Tarek A., El-Say, Khalid M., Abd-Allah, Fathy I., Omar, Abdelsattar M., El-Araby, Moustafa E., Muhammad, Yosra A., Pagare, Piyusha P., Zhang, Yan, Mohmmad, Khadijah A., Abdulmalik, Osheiza, Safo, Martin K.
Publicado 2021