Discovery of 3-((3-amino-1H-indazol-4-yl)ethynyl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide (AKE-72), a potent Pan-BCR-ABL inhibitor including the T3...

por El-Damasy, Ashraf K., Kim, Hyun Ji, Park, Jung Woo, Nam, Yunju, Hur, Wooyoung, Bang, Eun-Kyoung, Keum, Gyochang
Publicado 2023

Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors

por El-Damasy, Ashraf K., Park, Jong Eun, Kim, Hyun Ji, Lee, Jinhyuk, Bang, Eun-Kyoung, Kim, Hoon, Keum, Gyochang
Publicado 2023

Synthesis and Molecular Docking Study of New Thiazole Derivatives as Potential Tubulin Polymerization Inhibitors

por El-Abd, Azhar O., Bayomi, Said M., El-Damasy, Ashraf K., Mansour, Basem, Abdel-Aziz, Naglaa I., El-Sherbeny, Magda A.
Publicado 2022

Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII

por El-Damasy, Ashraf K., Kim, Hyun Ji, Nocentini, Alessio, Seo, Seon Hee, Eldehna, Wagdy M., Bang, Eun-Kyoung, Supuran, Claudiu T., Keum, Gyochang
Publicado 2023

Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole–Pyrimidine Derivatives as Potential Antiproliferative Agents

por El-Damasy, Ashraf K., Jin, Heewon, Sabry, Mohamed A., Kim, Hyun Ji, Alanazi, Mohammed M., Seo, Seon Hee, Bang, Eun-Kyoung, Keum, Gyochang
Publicado 2023

Discovery of New Quinolone-Based Diarylamides as Potent B-RAF(V600E)/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer Activity

por Kim, Hyun Ji, Park, Jung Woo, Seo, Sangjae, Cho, Kwang-Hwi, Alanazi, Mohammed M., Bang, Eun-Kyoung, Keum, Gyochang, El-Damasy, Ashraf K.
Publicado 2023

Docking Study, Synthesis, and Anti-Inflammatory Potential of Some New Pyridopyrimidine-Derived Compounds

por Abdelgawad, Mohamed A, Al-Sanea, Mohammad M, Musa, Arafa, Elmowafy, Mohammed, El-Damasy, Ashraf K, Azouz, Amany A, Ghoneim, Mohammed M, Bakr, Rania B
Publicado 2022

Overcoming the imatinib-resistant BCR-ABL mutants with new ureidobenzothiazole chemotypes endowed with potent and broad-spectrum anticancer activity

por El-Damasy, Ashraf K., Jin, Heewon, Park, Jung Woo, Kim, Hyun Ji, Khojah, Hanan, Seo, Seon Hee, Lee, Ju-Hyeon, Bang, Eun-Kyoung, Keum, Gyochang
Publicado 2023

Identification of Novel Potential VEGFR-2 Inhibitors Using a Combination of Computational Methods for Drug Discovery

por Al-Sanea, Mohammad M., Chilingaryan, Garri, Abelyan, Narek, Sargsyan, Arsen, Hovhannisyan, Sargis, Gasparyan, Hayk, Gevorgyan, Smbat, Albogami, Sarah, Ghoneim, Mohammed M., Farag, Ahmed K., Mohamed, Ahmed A. B., El-Damasy, Ashraf K.
Publicado 2021

Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90

por Shin, Sang Chul, El-Damasy, Ashraf K., Lee, Ju Hyeon, Seo, Seon Hee, Kim, Ji Hyun, Seo, Young Ho, Lee, Yuri, Yu, Ji Hoon, Bang, Eun Kyoung, Kim, Eunice EunKyeong, Keum, Gyochang
Publicado 2020

The Wound-Healing Potential of Olea europaea L. Cv. Arbequina Leaves Extract: An Integrated In Vitro, In Silico, and In Vivo Investigation

por Al-Warhi, Tarfah, Elmaidomy, Abeer H., Maher, Sherif A., Abu-Baih, Dalia H., Selim, Samy, Albqmi, Mha, Al-Sanea, Mohammad M., Alnusaire, Taghreed S., Ghoneim, Mohammed M., Mostafa, Ehab M., Hussein, Shaimaa, El-Damasy, Ashraf K., Saber, Entesar Ali, Elrehany, Mahmoud A., Sayed, Ahmed M., Othman, Eman M., El-Sherbiny, Mohamed, Abdelmohsen, Usama Ramadan
Publicado 2022