Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters

por Mast, Natalia, El-Darzi, Nicole, Li, Yong, Pikuleva, Irina A.
Publicado 2023

CYP46A1-dependent and independent effects of efavirenz treatment

por Mast, Natalia, El-Darzi, Nicole, Petrov, Alexey M, Li, Young, Pikuleva, Irina A
Publicado 2020

N,N-Dimethyl-3β-hydroxycholenamide Reduces Retinal Cholesterol via Partial Inhibition of Retinal Cholesterol Biosynthesis Rather Than its Liver X Receptor Transcriptional Activity

por El-Darzi, Nicole, Astafev, Artem, Mast, Natalia, Saadane, Aicha, Lam, Morrie, Pikuleva, Irina A.
Publicado 2018

The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina

por Petrov, Alexey M., Astafev, Artem A., Mast, Natalia, Saadane, Aicha, El-Darzi, Nicole, Pikuleva, Irina A.
Publicado 2019

Characterizations of Hamster Retina as a Model for Studies of Retinal Cholesterol Homeostasis

por El-Darzi, Nicole, Mast, Natalia, Dailey, Brian, Denker, John, Li, Yong, Vance, Joseph, Pikuleva, Irina A.
Publicado 2021

2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis

por El-Darzi, Nicole, Mast, Natalia, Hammer, Sandra S., Dorweiler, Tim F., Busik, Julia V., Pikuleva, Irina A.
Publicado 2022

The normalizing effects of the CYP46A1 activator efavirenz on retinal sterol levels and risk factors for glaucoma in Apoj(−/−) mice

por El-Darzi, Nicole, Mast, Natalia, Li, Yong, Dailey, Brian, Kang, Min, Rhee, Douglas J., Pikuleva, Irina A.
Publicado 2023

Low-Dose Anti-HIV Drug Efavirenz Mitigates Retinal Vascular Lesions in a Mouse Model of Alzheimer’s Disease

por El-Darzi, Nicole, Mast, Natalia, Buchner, David A., Saadane, Aicha, Dailey, Brian, Trichonas, Georgios, Pikuleva, Irina A.
Publicado 2022

Cholesterol crystal formation is a unifying pathogenic mechanism in the development of diabetic retinopathy

por Hammer, Sandra S., Dorweiler, Tim F., McFarland, Delaney, Adu-Agyeiwaah, Yvonne, Mast, Natalia, El-Darzi, Nicole, Fortmann, Seth D., Nooti, Sunil, Agrawal, Devendra K., Pikuleva, Irina A., Abela, George S., Grant, Maria B., Busik, Julia V.
Publicado 2023