Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4H,5H-pyrano[3,2-c]chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors

por Arif, Nadia, Shafiq, Zahid, Mahmood, Khalid, Rafiq, Muhammad, Naz, Sadia, Shahzad, Sohail Anjum, Farooq, Umar, Bahkali, Ali H., Elgorban, Abdallah M., Yaqub, Muhammad, El-Gokha, Ahmed
Publicado 2022

Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3

por Ansideri, Francesco, Macedo, Joana T., Eitel, Michael, El-Gokha, Ahmed, Zinad, Dhafer S., Scarpellini, Camilla, Kudolo, Mark, Schollmeyer, Dieter, Boeckler, Frank M., Blaum, Bärbel S., Laufer, Stefan A., Koch, Pierre
Publicado 2018

Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability

por Andreev, Stanislav, Pantsar, Tatu, El-Gokha, Ahmed, Ansideri, Francesco, Kudolo, Mark, Anton, Débora Bublitz, Sita, Giulia, Romasco, Jenny, Geibel, Christian, Lämmerhofer, Michael, Goettert, Márcia Ines, Tarozzi, Andrea, Laufer, Stefan A., Koch, Pierre
Publicado 2020

Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain

por Shaban, Elkhabiry, Świtalska, Marta, Wang, Li, Wang, Ning, Xiu, Fan, Hayashi, Ikuya, Ngoc, Tran Anh, Nagae, Sachie, El-Ghlban, Samah, Shimoda, Shiho, El Gokha, Ahmed Abdel Aleem, El Sayed, Ibrahim El Tantawy, Wietrzyk, Joanna, Inokuchi, Tsutomu
Publicado 2017

Cytotoxic Potential of Novel Quinoline Derivative: 11-(1,4-Bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline against Different Cancer Cell Lines via Activation and Deact...

por Abd Elrahman, Sara Fathy, Ahmed, Abdullah A. S., Abd Elsatar, Doaa, Elkady, Salma, Elgendy, Amira, Alnakeeb, Fatma, Elmongy, Elshaymaa I., Henidi, Hanan A., El-Gendy, Saad M., El Sayed, Ibrahim El Tantawy, El-Gokha, Ahmed A., Abd Eldaim, Mabrouk Attia
Publicado 2023