To live or to die: a matter of processing damaged DNA termini in neurons

por El-Khamisy, Sherif F
Publicado 2011

Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia

por Walker, Callum, El-Khamisy, Sherif F
Publicado 2018

TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy

por Alagoz, Meryem, Wells, Owen S., El-Khamisy, Sherif F.
Publicado 2014

DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat

por Boughey, Harvey, Jurga, Mateusz, El-Khamisy, Sherif F.
Publicado 2021

Editorial: Genomic Instability and Neurodegeneration

por Fuchs, Julia, Schwer, Bjoern, El-Khamisy, Sherif F.
Publicado 2022

ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells

por Alagoz, Meryem, Chiang, Shih-Chieh, Sharma, Abhishek, El-Khamisy, Sherif F.
Publicado 2013

TDP1/TOP1 Ratio as a Promising Indicator for the Response of Small Cell Lung Cancer to Topotecan

por Meisenberg, Cornelia, Ward, Simon E, Schmid, Peter, El-Khamisy, Sherif F
Publicado 2014

Rad5, HLTF, and SHPRH: A Fresh View of an Old Story

por Elserafy, Menattallah, Abugable, Arwa A., Atteya, Reham, El-Khamisy, Sherif F.
Publicado 2018

TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage

por Zeng, Zhihong, Cortés-Ledesma, Felipe, El Khamisy, Sherif F., Caldecott, Keith W.
Publicado 2011

Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development

por Zaksauskaite, Ringaile, Thomas, Ruth C, van Eeden, Freek, El-Khamisy, Sherif F.
Publicado 2021

USP11 controls R-loops by regulating senataxin proteostasis

por Jurga, Mateusz, Abugable, Arwa A., Goldman, Alastair S. H., El-Khamisy, Sherif F.
Publicado 2021

Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites

por Lebedeva, Natalia A., Rechkunova, Nadejda I., El-Khamisy, Sherif F., Lavrik, Olga I.
Publicado 2012

Gold nanoparticles – an optical biosensor for RNA quantification for cancer and neurologic disorders diagnosis

por Shawky, Sherif M, Awad, Ahmed M, Abugable, Arwa A, El-Khamisy, Sherif F
Publicado 2018

SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair

por Hudson, Jessica J.R., Chiang, Shih-Chieh, Wells, Owen S., Rookyard, Chris, El-Khamisy, Sherif F.
Publicado 2012

Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1

por Elsayed, Waheba, El-Shafie, Lamia, Hassan, Mohamed K., Farag, Mohamed A., El-Khamisy, Sherif F.
Publicado 2016

Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples

por Shawky, Sherif M., Awad, Ahmed M., Allam, Walaa, Alkordi, Mohamed H., EL-Khamisy, Sherif F.
Publicado 2017

Recent advances in stem cells therapy: A focus on cancer, Parkinson’s and Alzheimer’s

por Fleifel, Dalia, Rahmoon, Mai Atef, AlOkda, Abdelrahman, Nasr, Mostafa, Elserafy, Menattallah, El-Khamisy, Sherif F.
Publicado 2018

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

por Kok, Jannigje Rachel, Palminha, Nelma M., Dos Santos Souza, Cleide, El-Khamisy, Sherif F., Ferraiuolo, Laura
Publicado 2021

Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin

por El-Khamisy, Sherif F., Katyal, Sachin, Patel, Poorvi, Ju, Limei, McKinnon, Peter J., Caldecott, Keith W.
Publicado 2009

P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane

por Hassan, Mohamed Kamel, Watari, Hidemichi, Mitamura, Takashi, Mohamed, Zainab, EL-khamisy, Sherif F., Ohba, Yusuke, Sakuragi, Noriaki
Publicado 2015