Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology

por El-Sagheer, Afaf H., Brown, Tom
Publicado 2012

Efficient enzymatic synthesis and dual-colour fluorescent labelling of DNA probes using long chain azido-dUTP and BCN dyes

por Ren, Xiaomei, El-Sagheer, Afaf H., Brown, Tom
Publicado 2016

Artificial nucleic acid backbones and their applications in therapeutics, synthetic biology and biotechnology

por Epple, Sven, El-Sagheer, Afaf H., Brown, Tom
Publicado 2021

Combination probes with intercalating anchors and proximal fluorophores for DNA and RNA detection

por Qiu, Jieqiong, Wilson, Adam, El-Sagheer, Afaf H., Brown, Tom
Publicado 2016

Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA

por Kumar, Pawan, El-Sagheer, Afaf H., Truong, Lynda, Brown, Tom
Publicado 2017

An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA

por Taemaitree, Lapatrada, Shivalingam, Arun, El-Sagheer, Afaf H., Brown, Tom
Publicado 2019

Squaramides and Ureas: A Flexible Approach to Polymerase‐Compatible Nucleic Acid Assembly

por Shivalingam, Arun, Taemaitree, Lapatrada, El‐Sagheer, Afaf H., Brown, Tom
Publicado 2020

Assessing the biocompatibility of click-linked DNA in Escherichia coli

por Sanzone, A. Pia, El-Sagheer, Afaf H., Brown, Tom, Tavassoli, Ali
Publicado 2012

Force-induced melting of DNA—evidence for peeling and internal melting from force spectra on short synthetic duplex sequences

por Bosaeus, Niklas, El-Sagheer, Afaf H., Brown, Tom, Åkerman, Björn, Nordén, Bengt
Publicado 2014

Synthesis and biophysical properties of carbamate-locked nucleic acid (LNA) oligonucleotides with potential antisense applications

por Thorpe, Cameron, Epple, Sven, Woods, Benjamin, El-Sagheer, Afaf H., Brown, Tom
Publicado 2019

Enzyme-free synthesis of cyclic single-stranded DNA constructs containing a single triazole, amide or phosphoramidate backbone linkage and their use as templates for rolling circle...

por Chen, Jinfeng, Baker, Ysobel R., Brown, Asha, El-Sagheer, Afaf H., Brown, Tom
Publicado 2018

Design of thiazole orange oligonucleotide probes for detection of DNA and RNA by fluorescence and duplex melting

por Klimkowski, Piotr, De Ornellas, Sara, Singleton, Daniel, El-Sagheer, Afaf H., Brown, Tom
Publicado 2019

Molecular flexibility of DNA as a key determinant of RAD51 recruitment

por Paoletti, Federico, El‐Sagheer, Afaf H, Allard, Jun, Brown, Tom, Dushek, Omer, Esashi, Fumiko
Publicado 2020

Transcription of Click-Linked DNA in Human Cells**

por Birts, Charles N, Sanzone, A Pia, El-Sagheer, Afaf H, Blaydes, Jeremy P, Brown, Tom, Tavassoli, Ali
Publicado 2014

Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures

por Manuguerra, Ilenia, Croce, Stefano, El-Sagheer, Afaf H., Krissanaprasit, Abhichart, Brown, Tom, Gothelf, Kurt V., Manetto, Antonio
Publicado 2018

Expanding the chemical functionality of DNA nanomaterials generated by rolling circle amplification

por Baker, Ysobel R, Yuan, Liyiwen, Chen, Jinfeng, Belle, Roman, Carlisle, Robert, El-Sagheer, Afaf H, Brown, Tom
Publicado 2021

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA

por Dierckx, Anke, Dinér, Peter, El-Sagheer, Afaf H., Kumar, Joshi Dhruval, Brown, Tom, Grøtli, Morten, Wilhelmsson, L. Marcus
Publicado 2011

Preparation and characterization of manganese, cobalt and zinc DNA nanoflowers with tuneable morphology, DNA content and size

por Baker, Ysobel R, Chen, Jinfeng, Brown, Jason, El-Sagheer, Afaf H, Wiseman, Philip, Johnson, Errin, Goddard, Paul, Brown, Tom
Publicado 2018

Enzymatic Synthesis of Chemical Nuclease Triplex-Forming Oligonucleotides with Gene-Silencing Applications

por McGorman, Bríonna, Fantoni, Nicolò Zuin, O’Carroll, Sinéad, Ziemele, Anna, El-Sagheer, Afaf H, Brown, Tom, Kellett, Andrew
Publicado 2022

RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks

por Abdullah, Ummi B, McGouran, Joanna F, Brolih, Sanja, Ptchelkine, Denis, El‐Sagheer, Afaf H, Brown, Tom, McHugh, Peter J
Publicado 2017