Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue

por Couto Alves, Alexessander, Glastonbury, Craig A., El-Sayed Moustafa, Julia S., Small, Kerrin S.
Publicado 2018

Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs

por Glastonbury, Craig A., Couto Alves, Alexessander, El-Sayed Moustafa, Julia S., Small, Kerrin S.
Publicado 2019

Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable

por Zito, Antonino, Roberts, Amy L., Visconti, Alessia, Rossi, Niccolo’, Andres-Ejarque, Rosa, Nardone, Stefano, El-Sayed Moustafa, Julia S., Falchi, Mario, Small, Kerrin S.
Publicado 2023

Epigenetic findings in periodontitis in UK twins: a cross-sectional study

por Kurushima, Yuko, Tsai, Pei-Chien, Castillo-Fernandez, Juan, Couto Alves, Alexessander, El-Sayed Moustafa, Julia Sarah, Le Roy, Caroline, Spector, Tim D., Ide, Mark, Hughes, Francis J., Small, Kerrin S., Steves, Claire J., Bell, Jordana T.
Publicado 2019

Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans

por Roberts, Amy L, Morea, Alessandro, Amar, Ariella, Zito, Antonino, El-Sayed Moustafa, Julia S, Tomlinson, Max, Bowyer, Ruth CE, Zhang, Xinyuan, Christiansen, Colette, Costeira, Ricardo, Steves, Claire J, Mangino, Massimo, Bell, Jordana T, Wong, Chloe CY, Vyse, Timothy J, Small, Kerrin S
Publicado 2022

Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice

por Patel, Satish, Haider, Afreen, Alvarez-Guaita, Anna, Bidault, Guillaume, El-Sayed Moustafa, Julia Sarah, Guiu-Jurado, Esther, Tadross, John A., Warner, James, Harrison, James, Virtue, Samuel, Scurria, Fabio, Zvetkova, Ilona, Blüher, Matthias, Small, Kerrin S., O’Rahilly, Stephen, Savage, David B.
Publicado 2022

What Is the Contribution of Two Genetic Variants Regulating VEGF Levels to Type 2 Diabetes Risk and to Microvascular Complications?

por Bonnefond, Amélie, Saulnier, Pierre-Jean, Stathopoulou, Maria G., Grarup, Niels, Ndiaye, Ndeye Coumba, Roussel, Ronan, Nezhad, Mohsen Azimi, Dechaume, Aurélie, Lantieri, Olivier, Hercberg, Serge, Lauritzen, Torsten, Balkau, Beverley, El-Sayed Moustafa, Julia S., Hansen, Torben, Pedersen, Oluf, Froguel, Philippe, Charpentier, Guillaume, Marre, Michel, Hadjadj, Samy, Visvikis-Siest, Sophie
Publicado 2013

Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults

por Zazzara, Maria Beatrice, Penfold, Rose S, Roberts, Amy L, Lee, Karla A, Dooley, Hannah, Sudre, Carole H, Welch, Carly, Bowyer, Ruth C E, Visconti, Alessia, Mangino, Massimo, Freidin, Maxim B, El-Sayed Moustafa, Julia S, Small, Kerrin S, Murray, Benjamin, Modat, Marc, Graham, Mark S, Wolf, Jonathan, Ourselin, Sebastien, Martin, Finbarr C, Steves, Claire J, Lochlainn, Mary Ni
Publicado 2020

ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition

por El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Publicado 2020

Rare Genomic Structural Variants in Complex Disease: Lessons from the Replication of Associations with Obesity

por Walters, Robin G., Coin, Lachlan J. M., Ruokonen, Aimo, de Smith, Adam J., El-Sayed Moustafa, Julia S., Jacquemont, Sebastien, Elliott, Paul, Esko, Tõnu, Hartikainen, Anna-Liisa, Laitinen, Jaana, Männik, Katrin, Martinet, Danielle, Meyre, David, Nauck, Matthias, Schurmann, Claudia, Sladek, Rob, Thorleifsson, Gudmar, Thorsteinsdóttir, Unnur, Valsesia, Armand, Waeber, Gerard, Zufferey, Flore, Balkau, Beverley, Pattou, François, Metspalu, Andres, Völzke, Henry, Vollenweider, Peter, Stefansson, Kári, Järvelin, Marjo-Riitta, Beckmann, Jacques S., Froguel, Philippe, Blakemore, Alexandra I. F.
Publicado 2013

Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits

por Brotman, Sarah M., El-Sayed Moustafa, Julia S., Guan, Li, Broadaway, K. Alaine, Wang, Dongmeng, Jackson, Anne U., Welch, Ryan, Currin, Kevin W., Tomlinson, Max, Vadlamudi, Swarooparani, Stringham, Heather M., Roberts, Amy L., Lakka, Timo A., Oravilahti, Anniina, Silva, Lilian Fernandes, Narisu, Narisu, Erdos, Michael R., Yan, Tingfen, Bonnycastle, Lori L., Raulerson, Chelsea K., Raza, Yasrab, Yan, Xinyu, Parker, Stephen C.J., Kuusisto, Johanna, Pajukanta, Päivi, Tuomilehto, Jaakko, Collins, Francis S., Boehnke, Michael, Love, Michael I., Koistinen, Heikki A., Laakso, Markku, Mohlke, Karen L., Small, Kerrin S., Scott, Laura J.
Publicado 2023

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

por Small, Kerrin S., Todorčević, Marijana, Civelek, Mete, El-Sayed Moustafa, Julia S., Wang, Xiao, Simon, Michelle M., Fernandez-Tajes, Juan, Mahajan, Anubha, Horikoshi, Momoko, Hugill, Alison, Glastonbury, Craig A., Quaye, Lydia, Neville, Matt J., Sethi, Siddharth, Yon, Marianne, Pan, Calvin, Che, Nam, Viñuela, Ana, Tsai, Pei-Chien, Nag, Abhishek, Buil, Alfonso, Thorleifsson, Gudmar, Raghavan, Avanthi, Ding, Qiurong, Morris, Andrew P., Bell, Jordana T., Thorsteinsdottir, Unnur, Stefansson, Kari, Laakso, Markku, Dahlman, Ingrid, Arner, Peter, Gloyn, Anna L., Musunuru, Kiran, Lusis, Aldons J., Cox, Roger, Karpe, Fredrik, McCarthy, Mark I.
Publicado 2018

Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app

por Sudre, Carole H., Lee, Karla A., Lochlainn, Mary Ni, Varsavsky, Thomas, Murray, Benjamin, Graham, Mark S., Menni, Cristina, Modat, Marc, Bowyer, Ruth C. E., Nguyen, Long H., Drew, David A., Joshi, Amit D., Ma, Wenjie, Guo, Chuan-Guo, Lo, Chun-Han, Ganesh, Sajaysurya, Buwe, Abubakar, Pujol, Joan Capdevila, du Cadet, Julien Lavigne, Visconti, Alessia, Freidin, Maxim B., El-Sayed Moustafa, Julia S., Falchi, Mario, Davies, Richard, Gomez, Maria F., Fall, Tove, Cardoso, M. Jorge, Wolf, Jonathan, Franks, Paul W., Chan, Andrew T., Spector, Tim D., Steves, Claire J., Ourselin, Sébastien
Publicado 2021

ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19

por El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Acors, Sam, Kouphou, Neophytos, Wadge, Samuel, Duncan, Emma L., Steves, Claire J., Doores, Katie J., Malim, Michael H., Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Publicado 2022