Variability in the Log Domain and Limitations to Its Approximation by the Normal Distribution

por Elassaiss‐Schaap, Jeroen, Duisters, Kevin
Publicado 2020

Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC(50) Values in Aging and Alzheimer’s Disease, Using the Physiologically Based LeiCNS-PK3.0 Model

por Saleh, Mohammed A. A., Bloemberg, Julia S., Elassaiss-Schaap, Jeroen, de Lange, Elizabeth C. M.
Publicado 2022

Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3.0 simulations

por Saleh, Mohammed A. A., Loo, Chi Fong, Elassaiss-Schaap, Jeroen, De Lange, Elizabeth C. M.
Publicado 2021

The PBPK LeiCNS-PK3.0 framework predicts Nirmatrelvir (but not Remdesivir or Molnupiravir) to achieve effective concentrations against SARS-CoV-2 in human brain cells

por Saleh, Mohammed A.A., Hirasawa, Makoto, Sun, Ming, Gülave, Berfin, Elassaiss-Schaap, Jeroen, de Lange, Elizabeth C.M.
Publicado 2023

Crowdsourced Asparagus Urinary Odor Population Kinetics

por Ramamoorthy, Anuradha, Sadler, Brian M., van Hasselt, J.G. Coen, Elassaiss‐Schaap, Jeroen, Kasichayanula, Sreeneeranj, Edwards, Alena Y., van der Graaf, Piet H., Zhang, Lei, Wagner, John A.
Publicado 2017