Rational Design and In Vivo Characterization of mRNA-Encoded Broadly Neutralizing Antibody Combinations against HIV-1

por Narayanan, Elisabeth, Falcone, Samantha, Elbashir, Sayda M., Attarwala, Husain, Hassett, Kimberly, Seaman, Michael S., Carfi, Andrea, Himansu, Sunny
Publicado 2022

Altering the mRNA-1273 dosing interval impacts the kinetics, quality, and magnitude of immune responses in mice

por Garcia-Dominguez, Dario, Henry, Carole, Ma, LingZhi, Jani, Hardik, Amato, Nicholas J., Manning, Taylor, Freyn, Alec, Davis, Heather, Hsiao, Chiaowen Joyce, Li, Mengying, Koch, Hillary, Elbashir, Sayda, DiPiazza, Anthony, Carfi, Andrea, Edwards, Darin, Bahl, Kapil
Publicado 2022

mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2

por Darling, Tamarand L., Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Bricker, Traci L., Liang, Chieh-Yu, Joshi, Astha, Bamunuarachchi, Gayan, Seehra, Kuljeet, Schmitz, Aaron J., Halfmann, Peter J., Kawaoka, Yoshihiro, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S., Boon, Adrianus C.M.
Publicado 2022

Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice

por Ying, Baoling, Scheaffer, Suzanne M., Whitener, Bradley, Liang, Chieh-Yu, Dmytrenko, Oleksandr, Mackin, Samantha, Wu, Kai, Lee, Diana, Avena, Laura E., Chong, Zhenlu, Case, James Brett, Ma, LingZhi, Kim, Thu, Sein, Caralyn, Woods, Angela, Berrueta, Daniela Montes, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2022

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

por Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda, Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2021

Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

por Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2021

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

por Wu, Kai, Choi, Angela, Koch, Matthew, Elbashir, Sayda, Ma, LingZhi, Lee, Diana, Woods, Angela, Henry, Carole, Palandjian, Charis, Hill, Anna, Jani, Hardik, Quinones, Julian, Nunna, Naveen, O'Connell, Sarah, McDermott, Adrian B., Falcone, Samantha, Narayanan, Elisabeth, Colpitts, Tonya, Bennett, Hamilton, Corbett, Kizzmekia S., Seder, Robert, Graham, Barney S., Stewart-Jones, Guillaume B.E., Carfi, Andrea, Edwards, Darin K.
Publicado 2021

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant

por Scheaffer, Suzanne M., Lee, Diana, Whitener, Bradley, Ying, Baoling, Wu, Kai, Jani, Hardik, Martin, Philippa, Amato, Nicholas J., Avena, Laura E., Berrueta, Daniela Montes, Schmidt, Stephen D., O’Dell, Sijy, Nasir, Arshan, Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Koup, Richard A., Doria-Rose, Nicole A., Carfi, Andrea, Elbashir, Sayda M., Thackray, Larissa B., Edwards, Darin K., Diamond, Michael S.
Publicado 2022

Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice

por Ying, Baoling, Scheaffer, Suzanne M., Whitener, Bradley, Liang, Chieh-Yu, Dmytrenko, Oleksandr, Mackin, Samantha, Wu, Kai, Lee, Diana, Avena, Laura E., Chong, Zhenlu, Case, James Brett, Ma, LingZhi, Kim, Thu T.M., Sein, Caralyn E., Woods, Angela, Berrueta, Daniela Montes, Chang, Gwo-Yu, Stewart-Jones, Guillaume, Renzi, Isabella, Lai, Yen-Ting, Malinowski, Agata, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Publicado 2022

Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice

por Walls, Alexandra C., VanBlargan, Laura A., Wu, Kai, Choi, Angela, Navarro, Mary Jane, Lee, Diana, Avena, Laura, Berrueta, Daniela Montes, Pham, Minh N., Elbashir, Sayda, Kraft, John C., Miranda, Marcos C., Kepl, Elizabeth, Johnson, Max, Blackstone, Alyssa, Sprouse, Kaitlin, Fiala, Brooke, O’Connor, Megan A., Brunette, Natalie, Arunachalam, Prabhu S., Shirreff, Lisa, Rogers, Kenneth, Carter, Lauren, Fuller, Deborah H., Villinger, Francois, Pulendran, Bali, Diamond, Michael S., Edwards, Darin K., King, Neil P., Veesler, David
Publicado 2022

mRNA-1273 Protects against SARS-CoV-2 Beta Infection in Nonhuman Primates

por Corbett, Kizzmekia S., Werner, Anne P., O’ Connell, Sarah, Gagne, Matthew, Lai, Lilin, Moliva, Juan I., Flynn, Barbara, Choi, Angela, Koch, Matthew, Foulds, Kathryn E., Andrew, Shayne F., Flebbe, Dillon R., Lamb, Evan, Nurmukhambetova, Saule T., Provost, Samantha J., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Van Ry, Alex, Flinchbaugh, Zackery, Johnston, Timothy S., Mokhtari, Elham Bayat, Mudvari, Prakriti, Henry, Amy R., Laboune, Farida, Chang, Becky, Porto, Maciel, Wear, Jaclyn, Alvarado, Gabriela S., Boyoglu-Barnum, Seyhan, Todd, John-Paul M., Bart, Bridget, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Steingrebe, Katelyn, Elbashir, Sayda, Sriparna, Manjari, Pekosz, Andrew, Andersen, Hanne, Wu, Kai, Edwards, Darin K., Kar, Swagata, Lewis, Mark G., Boritz, Eli, Moore, Ian N., Carfi, Andrea, Suthar, Mehul S., McDermott, Adrian, Roederer, Mario, Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Seder, Robert A.
Publicado 2021

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

por Corbett, Kizzmekia S., Edwards, Darin K., Leist, Sarah R., Abiona, Olubukola M., Boyoglu-Barnum, Seyhan, Gillespie, Rebecca A., Himansu, Sunny, Schäfer, Alexandra, Ziwawo, Cynthia T., DiPiazza, Anthony T., Dinnon, Kenneth H., Elbashir, Sayda M., Shaw, Christine A., Woods, Angela, Fritch, Ethan J., Martinez, David R., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Hutchinson, Geoffrey B., Wu, Kai, Henry, Carole, Bahi, Kapil, Garcia-Dominguez, Dario, Ma, LingZhi, Renzi, Isabella, Kong, Wing-Pui, Schmidt, Stephen D., Wang, Lingshu, Zhang, Yi, Phung, Emily, Chang, Lauren A., Loomis, Rebecca J., Altaras, Nedim Emil, Narayanan, Elisabeth, Metkar, Mihir, Presnyak, Vlad, Liu, Cuiping, Louder, Mark K., Shi, Wei, Leung, Kwanyee, Yang, Eun Sung, West, Ande, Gully, Kendra L., Stevens, Laura J., Wang, Nianshuang, Wrapp, Daniel, Doria-Rose, Nicole A., Stewart-Jones, Guillaume, Bennett, Hamilton, Alvarado, Gabriela S., Nason, Martha C., Ruckwardt, Tracy J., McLellan, Jason S., Denison, Mark R., Chappell, James D., Moore, Ian N., Morabito, Kaitlyn M., Mascola, John R., Baric, Ralph S., Carfi, Andrea, Graham, Barney S.
Publicado 2020