Theophylline-based hybrids as acetylcholinesterase inhibitors endowed with anti-inflammatory activity: synthesis, bioevaluation, in silico and preliminary kinetic studies

por Elgazar, Abdullah A., El-Domany, Ramadan A., Eldehna, Wagdy M., Badria, Farid A.
Publicado 2023

3-Acetyl-11-keto-β-boswellic Acid-Based Hybrids Alleviate Acetaminophen-Induced Hepatotoxicity in HepG2 by the Regulation of Inflammatory and Oxidative Stress Pathways: An Integrat...

por Elgazar, Abdullah A., El-Domany, Ramadan A., Eldehna, Wagdy M., Badria, Farid A.
Publicado 2023

Design, Synthesis and Antitubercular Activity of Certain Nicotinic Acid Hydrazides

por Eldehna, Wagdy M., Fares, Mohamed, Abdel-Aziz, Marwa M., Abdel-Aziz, Hatem A.
Publicado 2015

Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor C...

por Abdel-Megied, Ahmed M., Eldehna, Wagdy M., Abdelrahman, Mohamed A., Elbarbry, Fawzy A.
Publicado 2020

Pyridine-Ureas as Potential Anticancer Agents: Synthesis and In Vitro Biological Evaluation

por El-Naggar, Mohamed, Almahli, Hadia, Ibrahim, Hany S., Eldehna, Wagdy M., Abdel-Aziz, Hatem A.
Publicado 2018

The old world salsola as a source of valuable secondary metabolites endowed with diverse pharmacological activities: a review

por ElNaggar, Mai H., Eldehna, Wagdy M., Abourehab, Mohammed A. S., Abdel Bar, Fatma M.
Publicado 2022

Identification of a New Potential SARS-COV-2 RNA-Dependent RNA Polymerase Inhibitor via Combining Fragment-Based Drug Design, Docking, Molecular Dynamics, and MM-PBSA Calculations

por El Hassab, Mahmoud A., Shoun, Aly A., Al-Rashood, Sara T., Al-Warhi, Tarfah, Eldehna, Wagdy M.
Publicado 2020

Olive Leaves as a Potential Phytotherapy in the Treatment of COVID-19 Disease; A Mini-Review

por Abdelgawad, Shimaa M., Hassab, Mahmoud A. El, Abourehab, Mohammed A. S., Elkaeed, Eslam B., Eldehna, Wagdy M.
Publicado 2022

Recent Advancements in the Development of Anti-Breast Cancer Synthetic Small Molecules

por Elkaeed, Eslam B., Salam, Hayam A. Abd El, Sabt, Ahmed, Al-Ansary, Ghada H., Eldehna, Wagdy M.
Publicado 2021

Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors

por Elsayed, Zainab M., Almahli, Hadia, Nocentini, Alessio, Ammara, Andrea, Supuran, Claudiu T., Eldehna, Wagdy M., Abou-Seri, Sahar M.
Publicado 2023

Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation

por Eldehna, Wagdy M., Hassan, Ghada S., Al-Rashood, Sara T., Alkahtani, Hamad M., A. Almehizia, Abdulrahman, Al-Ansary, Ghada H.
Publicado 2020

Dual Targeting of VEGFR2 and C-Met Kinases via the Design and Synthesis of Substituted 3-(Triazolo-thiadiazin-3-yl)indolin-2-one Derivatives as Angiogenesis Inhibitors

por Mohamady, Samy, Galal, Mahmoud, Eldehna, Wagdy M., Gutierrez, David C., Ibrahim, Hany S., Elmazar, Mohey M., Ali, Hamed I.
Publicado 2020

Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies

por Eldehna, Wagdy M., Al-Rashood, Sara T., Al-Warhi, Tarfah, Eskandrani, Razan O., Alharbi, Amal, El Kerdawy, Ahmed M.
Publicado 2020

In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches

por El Hassab, Mahmoud A., Ibrahim, Tamer M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Eldehna, Wagdy M.
Publicado 2021

GC/MS Analysis of Essential Oil and Enzyme Inhibitory Activities of Syzygium cumini (Pamposia) Grown in Egypt: Chemical Characterization and Molecular Docking Studies

por El-Nashar, Heba A. S., Eldehna, Wagdy M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Aly, Shaza H.
Publicado 2021

Synthesis, Crystal Study, and Anti-Proliferative Activity of Some 2-Benzimidazolylthioacetophenones towards Triple-Negative Breast Cancer MDA-MB-468 Cells as Apoptosis-Inducing Age...

por Abdel-Aziz, Hatem A., Eldehna, Wagdy M., Ghabbour, Hazem, Al-Ansary, Ghada H., Assaf, Areej M., Al-Dhfyan, Abdullah
Publicado 2016

New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres

por Attia, Mohamed I., Eldehna, Wagdy M., Afifi, Samar A., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A.
Publicado 2017

One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells

por Eldehna, Wagdy M., EL-Naggar, Dina H., Hamed, Ahmed R., Ibrahim, Hany S., Ghabbour, Hazem A., Abdel-Aziz, Hatem A.
Publicado 2017

Novel Thiazolidinone/Thiazolo[3,2-a]Benzimidazolone-Isatin Conjugates as Apoptotic Anti-proliferative Agents Towards Breast Cancer: One-Pot Synthesis and In Vitro Biological Evalua...

por El-Naggar, Mohamed, Eldehna, Wagdy M., Almahli, Hadia, Elgez, Amr, Fares, Mohamed, Elaasser, Mahmoud M., Abdel-Aziz, Hatem A.
Publicado 2018

Phytonutrients, Colorant Pigments, Phytochemicals, and Antioxidant Potential of Orphan Leafy Amaranthus Species

por Sarker, Umakanta, Rabbani, Md. Golam, Oba, Shinya, Eldehna, Wagdy M., Al-Rashood, Sara T., Mostafa, Nada M., Eldahshan, Omayma A.
Publicado 2022