Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

por Maertens, Goedele N, El Messaoudi-Aubert, Selma, Elderkin, Sarah, Hiom, Kevin, Peters, Gordon
Publicado 2010

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment

por Cooper, Sarah, Dienstbier, Martin, Hassan, Raihann, Schermelleh, Lothar, Sharif, Jafar, Blackledge, Neil P., De Marco, Valeria, Elderkin, Sarah, Koseki, Haruhiko, Klose, Robert, Heger, Andreas, Brockdorff, Neil
Publicado 2014

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression

por Kar, Gozde, Kim, Jong Kyoung, Kolodziejczyk, Aleksandra A., Natarajan, Kedar Nath, Torlai Triglia, Elena, Mifsud, Borbala, Elderkin, Sarah, Marioni, John C., Pombo, Ana, Teichmann, Sarah A.
Publicado 2017

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

por Tavares, Lígia, Dimitrova, Emilia, Oxley, David, Webster, Judith, Poot, Raymond, Demmers, Jeroen, Bezstarosti, Karel, Taylor, Stephen, Ura, Hiroki, Koide, Hiroshi, Wutz, Anton, Vidal, Miguel, Elderkin, Sarah, Brockdorff, Neil
Publicado 2012

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

por Tavares, Lígia, Dimitrova, Emilia, Oxley, David, Webster, Judith, Poot, Raymond, Demmers, Jeroen, Bezstarosti, Karel, Taylor, Stephen, Ura, Hiroki, Koide, Hiroshi, Wutz, Anton, Vidal, Miguel, Elderkin, Sarah, Brockdorff, Neil
Publicado 2012

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system

por Bruno, Ludovica, Ramlall, Vijendra, Studer, Romain A., Sauer, Stephan, Bradley, David, Dharmalingam, Gopuraja, Carroll, Thomas, Ghoneim, Mohamed, Chopin, Michaël, Nutt, Stephen L., Elderkin, Sarah, Rueda, David S., Fisher, Amanda G., Siggers, Trevor, Beltrao, Pedro, Merkenschlager, Matthias
Publicado 2019

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

por Novo, Clara Lopes, Tang, Calvin, Ahmed, Kashif, Djuric, Ugljesa, Fussner, Eden, Mullin, Nicholas P., Morgan, Natasha P., Hayre, Jasvinder, Sienerth, Arnold R., Elderkin, Sarah, Nishinakamura, Ryuichi, Chambers, Ian, Ellis, James, Bazett-Jones, David P., Rugg-Gunn, Peter J.
Publicado 2016

Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

por Koohy, Hashem, Bolland, Daniel J., Matheson, Louise S., Schoenfelder, Stefan, Stellato, Claudia, Dimond, Andrew, Várnai, Csilla, Chovanec, Peter, Chessa, Tamara, Denizot, Jeremy, Manzano Garcia, Raquel, Wingett, Steven W., Freire-Pritchett, Paula, Nagano, Takashi, Hawkins, Phillip, Stephens, Len, Elderkin, Sarah, Spivakov, Mikhail, Fraser, Peter, Corcoran, Anne E., Varga-Weisz, Patrick D.
Publicado 2018

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

por Schoenfelder, Stefan, Furlan-Magaril, Mayra, Mifsud, Borbala, Tavares-Cadete, Filipe, Sugar, Robert, Javierre, Biola-Maria, Nagano, Takashi, Katsman, Yulia, Sakthidevi, Moorthy, Wingett, Steven W., Dimitrova, Emilia, Dimond, Andrew, Edelman, Lucas B., Elderkin, Sarah, Tabbada, Kristina, Darbo, Elodie, Andrews, Simon, Herman, Bram, Higgs, Andy, LeProust, Emily, Osborne, Cameron S., Mitchell, Jennifer A., Luscombe, Nicholas M., Fraser, Peter
Publicado 2015