Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations

por Porkka, Noora, Valo, Satu, Nieminen, Taina T., Olkinuora, Alisa, Mäki-Nevala, Satu, Eldfors, Samuli, Peltomäki, Päivi
Publicado 2017

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas

por Porkka, Noora K., Olkinuora, Alisa, Kuopio, Teijo, Ahtiainen, Maarit, Eldfors, Samuli, Almusa, Henrikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2020

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

por Olkinuora, Alisa, Gylling, Annette, Almusa, Henrikki, Eldfors, Samuli, Lepistö, Anna, Mecklin, Jukka-Pekka, Nieminen, Taina Tuulikki, Peltomäki, Päivi
Publicado 2020

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer

por Kangaspeska, Sara, Hultsch, Susanne, Jaiswal, Alok, Edgren, Henrik, Mpindi, John-Patrick, Eldfors, Samuli, Brück, Oscar, Aittokallio, Tero, Kallioniemi, Olli
Publicado 2016

Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

por Eldfors, S, Kuusanmäki, H, Kontro, M, Majumder, M M, Parsons, A, Edgren, H, Pemovska, T, Kallioniemi, O, Wennerberg, K, Gökbuget, N, Burmeister, T, Porkka, K, Heckman, C A
Publicado 2017

Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation

por Andersson, E I, Rajala, H L M, Eldfors, S, Ellonen, P, Olson, T, Jerez, A, Clemente, M J, Kallioniemi, O, Porkka, K, Heckman, C, Loughran, T P, Maciejewski, J P, Mustjoki, S
Publicado 2013

Comparison of solution-based exome capture methods for next generation sequencing

por Sulonen, Anna-Maija, Ellonen, Pekka, Almusa, Henrikki, Lepistö, Maija, Eldfors, Samuli, Hannula, Sari, Miettinen, Timo, Tyynismaa, Henna, Salo, Perttu, Heckman, Caroline, Joensuu, Heikki, Raivio, Taneli, Suomalainen, Anu, Saarela, Janna
Publicado 2011

Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

por Malani, D, Murumägi, A, Yadav, B, Kontro, M, Eldfors, S, Kumar, A, Karjalainen, R, Majumder, M M, Ojamies, P, Pemovska, T, Wennerberg, K, Heckman, C, Porkka, K, Wolf, M, Aittokallio, T, Kallioniemi, O
Publicado 2017

Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

por Majumder, Muntasir Mamun, Silvennoinen, Raija, Anttila, Pekka, Tamborero, David, Eldfors, Samuli, Yadav, Bhagwan, Karjalainen, Riikka, Kuusanmäki, Heikki, Lievonen, Juha, Parsons, Alun, Suvela, Minna, Jantunen, Esa, Porkka, Kimmo, Heckman, Caroline A.
Publicado 2017

Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis

por Savola, P., Kelkka, T., Rajala, H. L., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagström, S., Lepistö, M., Hannunen, T., Andersson, E. I., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M., Mustjoki, S.
Publicado 2017

Somatic mutations and T-cell clonality in patients with immunodeficiency

por Savola, Paula, Martelius, Timi, Kankainen, Matti, Huuhtanen, Jani, Lundgren, Sofie, Koski, Yrjö, Eldfors, Samuli, Kelkka, Tiina, Keränen, Mikko A.I., Ellonen, Pekka, Kovanen, Panu E., Kytölä, Soili, Saarela, Janna, Lähdesmäki, Harri, Seppänen, Mikko R.J., Mustjoki, Satu
Publicado 2019

Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

por Kelkka, Tiina, Savola, Paula, Bhattacharya, Dipabarna, Huuhtanen, Jani, Lönnberg, Tapio, Kankainen, Matti, Paalanen, Kirsi, Tyster, Mikko, Lepistö, Maija, Ellonen, Pekka, Smolander, Johannes, Eldfors, Samuli, Yadav, Bhagwan, Khan, Sofia, Koivuniemi, Riitta, Sjöwall, Christopher, Elo, Laura L., Lähdesmäki, Harri, Maeda, Yuka, Nishikawa, Hiroyoshi, Leirisalo-Repo, Marjatta, Sokka-Isler, Tuulikki, Mustjoki, Satu
Publicado 2020

Corrigendum: Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

por Kelkka, Tiina, Savola, Paula, Bhattacharya, Dipabarna, Huuhtanen, Jani, Lönnberg, Tapio, Kankainen, Matti, Paalanen, Kirsi, Tyster, Mikko, Lepistö, Maija, Ellonen, Pekka, Smolander, Johannes, Eldfors, Samuli, Yadav, Bhagwan, Khan, Sofia, Koivuniemi, Riitta, Sjöwall, Christopher, Elo, Laura L., Lähdesmäki, Harri, Maeda, Yuka, Nishikawa, Hiroyoshi, Leirisalo-Repo, Marjatta, Sokka-Isler, Tuulikki, Mustjoki, Satu
Publicado 2021

Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease

por Kim, Daehong, Park, Giljun, Huuhtanen, Jani, Lundgren, Sofie, Khajuria, Rajiv K., Hurtado, Ana M., Muñoz-Calleja, Cecilia, Cardeñoso, Laura, Gómez-García de Soria, Valle, Chen-Liang, Tzu Hua, Eldfors, Samuli, Ellonen, Pekka, Hannula, Sari, Kankainen, Matti, Bruck, Oscar, Kreutzman, Anna, Salmenniemi, Urpu, Lönnberg, Tapio, Jerez, Andrés, Itälä-Remes, Maija, Myllymäki, Mikko, Keränen, Mikko A. I., Mustjoki, Satu
Publicado 2020

Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

por Malani, Disha, Kumar, Ashwini, Brück, Oscar, Kontro, Mika, Yadav, Bhagwan, Hellesøy, Monica, Kuusanmäki, Heikki, Dufva, Olli, Kankainen, Matti, Eldfors, Samuli, Potdar, Swapnil, Saarela, Jani, Turunen, Laura, Parsons, Alun, Västrik, Imre, Kivinen, Katja, Saarela, Janna, Räty, Riikka, Lehto, Minna, Wolf, Maija, Gjertsen, Bjorn Tore, Mustjoki, Satu, Aittokallio, Tero, Wennerberg, Krister, Heckman, Caroline A., Kallioniemi, Olli, Porkka, Kimmo
Publicado 2022

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

por Dufva, Olli, Kankainen, Matti, Kelkka, Tiina, Sekiguchi, Nodoka, Awad, Shady Adnan, Eldfors, Samuli, Yadav, Bhagwan, Kuusanmäki, Heikki, Malani, Disha, Andersson, Emma I, Pietarinen, Paavo, Saikko, Leena, Kovanen, Panu E., Ojala, Teija, Lee, Dean A., Loughran, Thomas P., Nakazawa, Hideyuki, Suzumiya, Junji, Suzuki, Ritsuro, Ko, Young Hyeh, Kim, Won Seog, Chuang, Shih-Sung, Aittokallio, Tero, Chan, Wing C., Ohshima, Koichi, Ishida, Fumihiro, Mustjoki, Satu
Publicado 2018

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

por Kuusanmäki, Heikki, Dufva, Olli, Vähä-Koskela, Markus, Leppä, Aino-Maija, Huuhtanen, Jani, Vänttinen, Ida, Nygren, Petra, Klievink, Jay, Bouhlal, Jonas, Pölönen, Petri, Zhang, Qi, Adnan-Awad, Shady, Mancebo-Pérez, Cristina, Saad, Joseph, Miettinen, Juho, Javarappa, Komal K., Aakko, Sofia, Ruokoranta, Tanja, Eldfors, Samuli, Heinäniemi, Merja, Theilgaard-Mönch, Kim, Wartiovaara-Kautto, Ulla, Keränen, Mikko, Porkka, Kimmo, Konopleva, Marina, Wennerberg, Krister, Kontro, Mika, Heckman, Caroline A., Mustjoki, Satu
Publicado 2023