Different Toll-Like Receptor Stimuli Have a Profound Impact on Cytokines Required to Break Tolerance and Induce Autoimmunity

por Lin, Albert C. C., Dissanayake, Dilan, Dhanji, Salim, Elford, Alisha R., Ohashi, Pamela S.
Publicado 2011

Peptide-Pulsed Dendritic Cells Have Superior Ability to Induce Immune-Mediated Tissue Destruction Compared to Peptide with Adjuvant

por Dissanayake, Dilan, Murakami, Kiichi, Tran, Michael D., Elford, Alisha R., Millar, Douglas G., Ohashi, Pamela S.
Publicado 2014

Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

por Nguyen, Linh T., Elford, Alisha R., Murakami, Kiichi, Garza, Kristine M., Schoenberger, Stephen P., Odermatt, Bernhard, Speiser, Daniel E., Ohashi, Pamela S.
Publicado 2002

Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes

por Ono, Nobuyuki, Murakami, Kiichi, Chan, Olivia, Hall, Håkan, Elford, Alisha R., Yen, Patty, Calzascia, Thomas, Spencer, David M., Ohashi, Pamela S., Dhanji, Salim
Publicado 2017

Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity

por Tran, Charles W., Gold, Matthew J., Garcia-Batres, Carlos, Tai, Kelly, Elford, Alisha R., Himmel, Megan E., Elia, Andrew J., Ohashi, Pamela S.
Publicado 2020

PKCθ Signals Activation versus Tolerance In Vivo

por Berg-Brown, Nancy N., Gronski, Matthew A., Jones, Russell G., Elford, Alisha R., Deenick, Elissa K., Odermatt, Bernhard, Littman, Dan R., Ohashi, Pamela S.
Publicado 2004

Overproduction of IL-2 by Cbl-b deficient CD4(+) T cells provides resistance against regulatory T cells

por Han, SeongJun, Chung, Douglas C., St. Paul, Michael, Liu, Zhe Qi, Garcia-Batres, Carlos, Elford, Alisha R., Tran, Charles W., Chapatte, Laurence, Ohashi, Pamela S.
Publicado 2020

CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly

por Jones, Russell G., Elford, Alisha R., Parsons, Michael J., Wu, Linda, Krawczyk, Connie M., Yeh, Wen-Chen, Hakem, Razqallah, Rottapel, Robert, Woodgett, James R., Ohashi, Pamela S.
Publicado 2002

Overproduction of IFNγ by Cbl-b–Deficient CD8(+) T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity

por Han, SeongJun, Liu, Zhe Qi, Chung, Douglas C., Paul, Michael St., Garcia-Batres, Carlos R., Sayad, Azin, Elford, Alisha R., Gold, Matthew J., Grimshaw, Natasha, Ohashi, Pamela S.
Publicado 2022

Cellular FLICE-inhibitory protein is required for T cell survival and cycling

por Chau, Hien, Wong, Veronica, Chen, Nien-Jung, Huang, Huey-Lan, Lin, Wen-Jye, Mirtsos, Christine, Elford, Alisha R., Bonnard, Madeleine, Wakeham, Andrew, You-Ten, Annick Itie, Lemmers, Bénédicte, Salmena, Leonardo, Pellegrini, Marc, Hakem, Razq, Mak, Tak W., Ohashi, Pamela, Yeh, Wen-Chen
Publicado 2005

Development of an adoptive cell therapy protocol with tumor-infiltrating lymphocytes and intermediate-dose interleukin-2 therapy

por Nguyen, Linh T, Butler, Marcus O, Yen, Pei Hua, Nie, Jessica, Pniak, Michael, Elford, Alisha R, Joshua, Anthony M, Hogg, David, Ghazarian, Danny, Al-Habeeb, Ayman, Easson, Alexandra M, Leong, Wey L, McCready, David R, Reedijk, Michael, Messner, Hans A, Ohashi, Pamela S
Publicado 2013

NK Cells Regulate CD8(+) T Cell Mediated Autoimmunity

por Lang, Philipp A., Crome, Sarah Q., Xu, Haifeng C., Lang, Karl S., Chapatte, Laurence, Deenick, Elissa K., Grusdat, Melanie, Pandyra, Aleksandra A., Pozdeev, Vitaly I., Wang, Ruifeng, Holderried, Tobias A. W., Cantor, Harvey, Diefenbach, Andreas, Elford, Alisha R., McIlwain, David R., Recher, Mike, Häussinger, Dieter, Mak, Tak W., Ohashi, Pamela S.
Publicado 2020

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

por Hao, Zhenyue, Sheng, Yi, Duncan, Gordon S., Li, Wanda Y., Dominguez, Carmen, Sylvester, Jennifer, Su, Yu-Wen, Lin, Gloria H.Y., Snow, Bryan E., Brenner, Dirk, You-Ten, Annick, Haight, Jillian, Inoue, Satoshi, Wakeham, Andrew, Elford, Alisha, Hamilton, Sara, Liang, Yi, Zúñiga-Pflücker, Juan C., He, Housheng Hansen, Ohashi, Pamela S., Mak, Tak W.
Publicado 2017

Loss of the signaling adaptor TRAF1 causes CD8(+) T cell dysregulation during human and murine chronic infection

por Wang, Chao, McPherson, Ann J., Jones, R. Brad, Kawamura, Kim S., Lin, Gloria H.Y., Lang, Philipp A., Ambagala, Thanuja, Pellegrini, Marc, Calzascia, Thomas, Aidarus, Nasra, Elford, Alisha R., Yue, Feng Yun, Kremmer, Elisabeth, Kovacs, Colin M., Benko, Erika, Tremblay, Cecile, Routy, Jean-Pierre, Bernard, Nicole F., Ostrowski, Mario A., Ohashi, Pamela S., Watts, Tania H.
Publicado 2012