Mechanisms of neratinib resistance in HER2-mutant metastatic breast cancer

por Eli, Lisa D., Kavuri, Shyam M.
Publicado 2022

Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast...

por Collins, Denis M., Conlon, Neil T., Kannan, Srinivasaraghavan, Verma, Chandra S., Eli, Lisa D., Lalani, Alshad S., Crown, John
Publicado 2019

PI3K and MAPK Pathways as Targets for Combination with the Pan-HER Irreversible Inhibitor Neratinib in HER2-Positive Breast Cancer and TNBC by Kinome RNAi Screening

por Lee, Jangsoon, Liu, Huey, Pearson, Troy, Iwase, Toshiaki, Fuson, Jon, Lalani, Alshad S., Eli, Lisa D., Diala, Irmina, Tripathy, Debu, Lim, Bora, Ueno, Naoto T.
Publicado 2021

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors

por Conlon, Neil T., Kooijman, Jeffrey J., van Gerwen, Suzanne J. C., Mulder, Winfried R., Zaman, Guido J. R., Diala, Irmina, Eli, Lisa D., Lalani, Alshad S., Crown, John, Collins, Denis M.
Publicado 2021

Biomarker Analysis of the Phase III NALA Study of Neratinib + Capecitabine versus Lapatinib + Capecitabine in Patients with Previously Treated Metastatic Breast Cancer

por Saura, Cristina, Matito, Judit, Oliveira, Mafalda, Wildiers, Hans, Brufksy, Adam M., Waters, Simon H., Hurvitz, Sara A., Moy, Beverly, Kim, Sung-Bae, Gradishar, William J., Queiroz, Geraldo Silva, Cronemberger, Eduardo, Wallweber, Gerald J., Bebchuk, Judith, Keyvanjah, Kiana, Lalani, Alshad S., Bryce, Richard, Vivancos, Ana, Eli, Lisa D., Delaloge, Suzette
Publicado 2021

PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial

por Chia, Stephen K. L., Martin, Miguel, Holmes, Frankie A., Ejlertsen, Bent, Delaloge, Suzette, Moy, Beverly, Iwata, Hiroji, von Minckwitz, Gunter, Mansi, Janine, Barrios, Carlos H., Gnant, Michael, Tomašević, Zorica, Denduluri, Neelima, Šeparović, Robert, Kim, Sung-Bae, Jakobsen, Erik Hugger, Harvey, Vernon, Robert, Nicholas, Smith, John, Harker, Graydon, Zhang, Bo, Eli, Lisa D., Ye, Yining, Lalani, Alshad S., Buyse, Marc, Chan, Arlene
Publicado 2019

Neratinib in patients with HER2-mutant, metastatic cervical cancer: Findings from the phase 2 SUMMIT basket trial

por Oaknin, Ana, Friedman, Claire F., Roman, Lynda D., D’Souza, Anishka, Brana, Irene, Bidard, François-Clement, Goldman, Jonathan, Alvarez, Edwin A., Boni, Valentina, ElNaggar, Adam C., Passalacqua, Rodolfo, Do, Khanh T.M., Santin, Alessandro D., Keyvanjah, Kiana, Xu, Feng, Eli, Lisa D., Lalani, Alshad S., Bryce, Richard P., Hyman, David M., Meric-Bernstam, Funda, Solit, David B., Monk, Bradley J.
Publicado 2020

Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers

por Harding, James J., Piha-Paul, Sarina A., Shah, Ronak H., Murphy, Jessica J., Cleary, James M., Shapiro, Geoffrey I., Quinn, David I., Braña, Irene, Moreno, Victor, Borad, Mitesh, Loi, Sherene, Spanggaard, Iben, Park, Haeseong, Ford, James M., Arnedos, Mónica, Stemmer, Salomon M., de la Fouchardiere, Christelle, Fountzilas, Christos, Zhang, Jie, DiPrimeo, Daniel, Savin, Casey, Duygu Selcuklu, S., Berger, Michael F., Eli, Lisa D., Meric-Bernstam, Funda, Jhaveri, Komal, Solit, David B., Abou-Alfa, Ghassan K.
Publicado 2023

HER kinase inhibition in patients with HER2- and HER3-mutant cancers

por Hyman, David M., Piha-Paul, Sarina A., Won, Helen, Rodon, Jordi, Saura, Cristina, Shapiro, Geoffrey I., Juric, Dejan, Quinn, David I., Moreno, Victor, Doger, Bernard, Mayer, Ingrid A., Boni, Valentina, Calvo, Emiliano, Loi, Sherene, Lockhart, Albert C., Erinjeri, Joseph P., Scaltriti, Maurizio, Ulaner, Gary A., Patel, Juber, Tang, Jiabin, Beer, Hannah, Selcuklu, S. Duygu, Hanrahan, Aphrothiti J., Bouvier, Nancy, Melcer, Myra, Murali, Rajmohan, Schram, Alison M., Smyth, Lillian M., Jhaveri, Komal, Li, Bob T., Drilon, Alexander, Harding, James J., Iyer, Gopa, Taylor, Barry S., Berger, Michael F., Cutler, Richard E., Xu, Feng, Butturini, Anna, Eli, Lisa D., Mann, Grace, Farrell, Cynthia, Lalani, Alshad S., Bryce, Richard P., Arteaga, Carlos L., Meric-Bernstam, Funda, Baselga, José, Solit, David B.
Publicado 2018