The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network

por Ellenbroek, Saskia I. J., Iden, Sandra, Collard, John G.
Publicado 2012

In Vivo Imaging Reveals Existence of Crypt Fission and Fusion in Adult Mouse Intestine

por Bruens, Lotte, Ellenbroek, Saskia I.J., van Rheenen, Jacco, Snippert, Hugo J.
Publicado 2017

Brief Report: Intravital Imaging of Cancer Stem Cell Plasticity in Mammary Tumors

por Zomer, Anoek, Ellenbroek, Saskia Inge Johanna, Ritsma, Laila, Beerling, Evelyne, Vrisekoop, Nienke, Van Rheenen, Jacco
Publicado 2013

Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT

por Bornes, Laura, van Scheppingen, Roan Hugo, Beerling, Evelyne, Schelfhorst, Tim, Ellenbroek, Saskia Inge Johanna, Seinstra, Danielle, van Rheenen, Jacco
Publicado 2019

Stem cell lineage survival as a noisy competition for niche access

por Corominas-Murtra, Bernat, Scheele, Colinda L. G. J., Kishi, Kasumi, Ellenbroek, Saskia I. J., Simons, Benjamin D., van Rheenen, Jacco, Hannezo, Edouard
Publicado 2020

Intestinal crypt homeostasis revealed at single stem cell level by in vivo live-imaging

por Ritsma, Laila, Ellenbroek, Saskia I.J., Zomer, Anoek, Snippert, Hugo J., de Sauvage, Frederic J., Simons, Benjamin D., Clevers, Hans, van Rheenen, Jacco
Publicado 2014

Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations

por Huelsz-Prince, Guizela, Kok, Rutger Nico Ulbe, Goos, Yvonne, Bruens, Lotte, Zheng, Xuan, Ellenbroek, Saskia, Van Rheenen, Jacco, Tans, Sander, van Zon, Jeroen S
Publicado 2022

An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency

por López, Ignacio, Chalatsi, Eleftheria, Ellenbroek, Saskia I. J., Andrieux, Alexandra, Roux, Pierre-François, Cerapio, Juan P., Jouvion, Grégory, van Rheenen, Jacco, Seeler, Jacob-S., Dejean, Anne
Publicado 2020

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine

por Bruens, Lotte, Ellenbroek, Saskia Inge Johanna, Suijkerbuijk, Saskia Jacoba Elisabeth, Azkanaz, Maria, Hale, Alexander James, Toonen, Pim, Flanagan, Dustin James, Sansom, Owen James, Snippert, Hugo Johannes, van Rheenen, Jacco
Publicado 2020

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

por Zomer, Anoek, Maynard, Carrie, Verweij, Frederik Johannes, Kamermans, Alwin, Schäfer, Ronny, Beerling, Evelyne, Schiffelers, Raymond Michel, de Wit, Elzo, Berenguer, Jordi, Ellenbroek, Saskia Inge Johanna, Wurdinger, Thomas, Pegtel, Dirk Michiel, van Rheenen, Jacco
Publicado 2015

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

por Fumagalli, Arianna, Oost, Koen C., Kester, Lennart, Morgner, Jessica, Bornes, Laura, Bruens, Lotte, Spaargaren, Lisa, Azkanaz, Maria, Schelfhorst, Tim, Beerling, Evelyne, Heinz, Maria C., Postrach, Daniel, Seinstra, Danielle, Sieuwerts, Anieta M., Martens, John W.M., van der Elst, Stefan, van Baalen, Martijn, Bhowmick, Debajit, Vrisekoop, Nienke, Ellenbroek, Saskia I.J., Suijkerbuijk, Saskia J.E., Snippert, Hugo J., van Rheenen, Jacco
Publicado 2020

Retrograde movements determine effective stem cell numbers in the intestine

por Azkanaz, Maria, Corominas-Murtra, Bernat, Ellenbroek, Saskia I.J., Bruens, Lotte, Webb, Anna T., Laskaris, Dimitrios, Oost, Koen C., Lafirenze, Simona J.A., Annusver, Karl, Messal, Hendrik A., Iqbal, Sharif, Flanagan, Dustin J., Huels, David J., Rojas-Rodríguez, Felipe, Vizoso, Miguel, Kasper, Maria, Sansom, Owen J., Snippert, Hugo J., Liberali, Prisca, Simons, Benjamin D., Katajisto, Pekka, Hannezo, Edouard, van Rheenen, Jacco
Publicado 2022