P332: LIN28B: AN IMPORTANT ONCO-FETAL GENE IN INFANT ACUTE LYMPHOBLASTIC LEUKAEMIA

por Ling, Rebecca, Jackson, Thomas, Elliott, Natalina, Cross, Joe, Rice, Siobhan, Howitt, Rebecca, Smith, Alastair, Harman, Joe, T Crump, Nicholas, Wang, Guanlin, Iskander, Deena, Thongjuea, Supat, Ancliff, Philip, Psaila, Beth, Roberts, Irene, Milne, Thomas, Roy, Anindita
Publicado 2023

Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development

por Roy, Anindita, Wang, Guanlin, Iskander, Deena, O’Byrne, Sorcha, Elliott, Natalina, O’Sullivan, Jennifer, Buck, Gemma, Heuston, Elisabeth F., Wen, Wei Xiong, Meira, Alba Rodriguez, Hua, Peng, Karadimitris, Anastasios, Mead, Adam J., Bodine, David M., Roberts, Irene, Psaila, Bethan, Thongjuea, Supat
Publicado 2021

Accelerated epigenetic aging in newborns with Down syndrome

por Xu, Keren, Li, Shaobo, Muskens, Ivo S., Elliott, Natalina, Myint, Swe Swe, Pandey, Priyatama, Hansen, Helen M., Morimoto, Libby M., Kang, Alice Y., Ma, Xiaomei, Metayer, Catherine, Mueller, Beth A., Roberts, Irene, Walsh, Kyle M., Horvath, Steve, Wiemels, Joseph L., de Smith, Adam J.
Publicado 2022

LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways

por Smith, Stephen, Tripathi, Rati, Goodings, Charnise, Cleveland, Susan, Mathias, Elizabeth, Hardaway, J. Andrew, Elliott, Natalina, Yi, Yajun, Chen, Xi, Downing, James, Mullighan, Charles, Swing, Deborah A., Tessarollo, Lino, Li, Liqi, Love, Paul, Jenkins, Nancy A., Copeland, Neal G., Thompson, Mary Ann, Du, Yang, Davé, Utpal P.
Publicado 2014

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

por Rice, Siobhan, Jackson, Thomas, Crump, Nicholas T., Fordham, Nicholas, Elliott, Natalina, O’Byrne, Sorcha, Fanego, Maria del Mar Lara, Addy, Dilys, Crabb, Trisevgeni, Dryden, Carryl, Inglott, Sarah, Ladon, Dariusz, Wright, Gary, Bartram, Jack, Ancliff, Philip, Mead, Adam J., Halsey, Christina, Roberts, Irene, Milne, Thomas A., Roy, Anindita
Publicado 2021

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

por Godfrey, Laura, Crump, Nicholas T., O’Byrne, Sorcha, Lau, I-Jun, Rice, Siobhan, Harman, Joe R., Jackson, Thomas, Elliott, Natalina, Buck, Gemma, Connor, Christopher, Thorne, Ross, Knapp, David J. H. F., Heidenreich, Olaf, Vyas, Paresh, Menendez, Pablo, Inglott, Sarah, Ancliff, Philip, Geng, Huimin, Roberts, Irene, Roy, Anindita, Milne, Thomas A.
Publicado 2020

Epigenome-wide association study of acute lymphoblastic leukemia in children with Down syndrome

por Li, Shaobo, Sok, Pagna, Xu, Keren, Muskens, Ivo S., Elliott, Natalina, Myint, Swe Swe, Pandey, Priyatama, Hansen, Helen M., Morimoto, Libby M., Kang, Alice Y., Metayer, Catherine, Ma, Xiaomei, Mueller, Beth A., Roy, Anindita, Roberts, Irene, Rabin, Karen R., Brown, Austin L., Lupo, Philip J., Wiemels, Joseph L., de Smith, Adam J.
Publicado 2022

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

por Louka, Eleni, Povinelli, Benjamin, Rodriguez-Meira, Alba, Buck, Gemma, Wen, Wei Xiong, Wang, Guanlin, Sousos, Nikolaos, Ashley, Neil, Hamblin, Angela, Booth, Christopher A.G., Roy, Anindita, Elliott, Natalina, Iskander, Deena, de la Fuente, Josu, Fordham, Nicholas, O’Byrne, Sorcha, Inglott, Sarah, Norfo, Ruggiero, Salio, Mariolina, Thongjuea, Supat, Rao, Anupama, Roberts, Irene, Mead, Adam J.
Publicado 2021

Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies

por Khan, Abdullah O., Rodriguez-Romera, Antonio, Reyat, Jasmeet S., Olijnik, Aude-Anais, Colombo, Michela, Wang, Guanlin, Wen, Wei Xiong, Sousos, Nikolaos, Murphy, Lauren C., Grygielska, Beata, Perrella, Gina, Mahony, Christopher B., Ling, Rebecca E., Elliott, Natalina E., Karali, Christina Simoglou, Stone, Andrew P., Kemble, Samuel, Cutler, Emily A., Fielding, Adele K., Croft, Adam P., Bassett, David, Poologasundarampillai, Gowsihan, Roy, Anindita, Gooding, Sarah, Rayes, Julie, Machlus, Kellie R., Psaila, Bethan
Publicado 2023