Targeting Cell Senescence to Improve Cardiac Regeneration

por Ellison-Hughes, Georgina M.
Publicado 2023

First evidence that senolytics are effective at decreasing senescent cells in humans

por Ellison-Hughes, Georgina M.
Publicado 2020

Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery()

por Ellison-Hughes, Georgina M., Madeddu, Paolo
Publicado 2017

A protocol for extracting immunolabeled murine cardiomyocytes of high-quality RNA by laser capture microdissection

por Shaalan, Abeer K., Ellison-Hughes, Georgina M.
Publicado 2022

Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo

por Cottle, Beverley J., Lewis, Fiona C., Shone, Victoria, Ellison-Hughes, Georgina M.
Publicado 2017

Cardiac Stem Cells for Myocardial Regeneration: They Are Not Alone

por Leong, Yin Yee, Ng, Wai Hoe, Ellison-Hughes, Georgina M., Tan, Jun Jie
Publicado 2017

Imatinib Mesylate Induces Necroptotic Cell Death and Impairs Autophagic Flux in Human Cardiac Progenitor Cells

por Walmsley, Robert, Steele, Derek S., Ellison-Hughes, Georgina M., Papaspyros, Sotiris, Smith, Andrew J.
Publicado 2022

Vascular Manifestations of COVID-19 – Thromboembolism and Microvascular Dysfunction

por Roberts, Kirsty A., Colley, Liam, Agbaedeng, Thomas A., Ellison-Hughes, Georgina M., Ross, Mark D.
Publicado 2020

The Role of MSC Therapy in Attenuating the Damaging Effects of the Cytokine Storm Induced by COVID-19 on the Heart and Cardiovascular System

por Ellison-Hughes, Georgina M., Colley, Liam, O'Brien, Katie A., Roberts, Kirsty A., Agbaedeng, Thomas A., Ross, Mark D.
Publicado 2020

Senescent Cells: A Therapeutic Target in Cardiovascular Diseases

por Suda, Masayoshi, Paul, Karl H., Minamino, Tohru, Miller, Jordan D., Lerman, Amir, Ellison-Hughes, Georgina M., Tchkonia, Tamar, Kirkland, James L.
Publicado 2023

Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease

por Cianflone, Eleonora, Torella, Michele, Biamonte, Flavia, De Angelis, Antonella, Urbanek, Konrad, Costanzo, Francesco S., Rota, Marcello, Ellison-Hughes, Georgina M., Torella, Daniele
Publicado 2020

Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells

por Smith, Andrew J., Ruchaya, Prashant, Walmsley, Robert, Wright, Kathleen E., Lewis-McDougall, Fiona C., Bond, Jacquelyn, Ellison-Hughes, Georgina M.
Publicado 2022

Transplantation of Skeletal Muscle-Derived Sca-1(+)/PW1(+)/Pax7(−) Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Inf...

por Ruchaya, Prashant J, Lewis-McDougall, Fiona C., Sornkarn, Nitiphat, Amin, Sachin, Grimsdell, Benjamin, Shaalan, Abeer, Gritti, Guilia, Soe, Kyi Thar, Clark, James E., Ellison-Hughes, Georgina M.
Publicado 2022

Transplantation of Allogeneic PW1(pos)/Pax7(neg) Interstitial Cells Enhance Endogenous Repair of Injured Porcine Skeletal Muscle

por Lewis, Fiona C., Cottle, Beverley J., Shone, Victoria, Marazzi, Giovanna, Sassoon, David, Tseng, Cheyenne C.S., Dankers, Patricia Y.W., Chamuleau, Steven A.J., Nadal-Ginard, Bernardo, Ellison-Hughes, Georgina M.
Publicado 2017

A Mouse Model of Dilated Cardiomyopathy Produced by Isoproterenol Acute Exposure Followed by 5-Fluorouracil Administration

por Salerno, Nadia, Scalise, Mariangela, Marino, Fabiola, Filardo, Andrea, Chiefalo, Antonio, Panuccio, Giuseppe, Torella, Michele, De Angelis, Antonella, De Rosa, Salvatore, Ellison-Hughes, Georgina M., Urbanek, Konrad, Viglietto, Giuseppe, Torella, Daniele, Cianflone, Eleonora
Publicado 2023

Aged‐senescent cells contribute to impaired heart regeneration

por Lewis‐McDougall, Fiona C., Ruchaya, Prashant J., Domenjo‐Vila, Eva, Shin Teoh, Tze, Prata, Larissa, Cottle, Beverley J., Clark, James E., Punjabi, Prakash P., Awad, Wael, Torella, Daniele, Tchkonia, Tamara, Kirkland, James L., Ellison‐Hughes, Georgina M.
Publicado 2019

Correction: c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration

por Aquila, Iolanda, Cianflone, Eleonora, Scalise, Mariangela, Marino, Fabiola, Mancuso, Teresa, Filardo, Andrea, Smith, Andrew J., Cappetta, Donato, De Angelis, Antonella, Urbanek, Konrad, Isidori, Andrea M., Torella, Michele, Agosti, Valter, Viglietto, Giuseppe, Nadal-Ginard, Bernardo, Ellison-Hughes, Georgina M., Torella, Daniele
Publicado 2023

c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration

por Aquila, Iolanda, Cianflone, Eleonora, Scalise, Mariangela, Marino, Fabiola, Mancuso, Teresa, Filardo, Andrea, Smith, Andrew J., Cappetta, Donato, De Angelis, Antonella, Urbanek, Konrad, Isidori, Andrea M., Torella, Michele, Agosti, Valter, Viglietto, Giuseppe, Nadal-Ginard, Bernardo, Ellison-Hughes, Georgina M., Torella, Daniele
Publicado 2019

Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification

por Vicinanza, Carla, Aquila, Iolanda, Scalise, Mariangela, Cristiano, Francesca, Marino, Fabiola, Cianflone, Eleonora, Mancuso, Teresa, Marotta, Pina, Sacco, Walter, Lewis, Fiona C, Couch, Liam, Shone, Victoria, Gritti, Giulia, Torella, Annalaura, Smith, Andrew J, Terracciano, Cesare MN, Britti, Domenico, Veltri, Pierangelo, Indolfi, Ciro, Nadal-Ginard, Bernardo, Ellison-Hughes, Georgina M, Torella, Daniele
Publicado 2017

Atrial myxomas arise from multipotent cardiac stem cells

por Scalise, Mariangela, Torella, Michele, Marino, Fabiola, Ravo, Maria, Giurato, Giorgio, Vicinanza, Carla, Cianflone, Eleonora, Mancuso, Teresa, Aquila, Iolanda, Salerno, Luca, Nassa, Giovanni, Agosti, Valter, De Angelis, Antonella, Urbanek, Konrad, Berrino, Liberato, Veltri, Pierangelo, Paolino, Donatella, Mastroroberto, Pasquale, De Feo, Marisa, Viglietto, Giuseppe, Weisz, Alessandro, Nadal-Ginard, Bernardo, Ellison-Hughes, Georgina M, Torella, Daniele
Publicado 2020