Inositol hexakisphosphate is required for Integrator function

por Lin, Min-Han, Jensen, Madeline K., Elrod, Nathan D., Huang, Kai-Lieh, Welle, Kevin A., Wagner, Eric J., Tong, Liang
Publicado 2022

Zika Virus Infection Alters Gene Expression and Poly-Adenylation Patterns in Placental Cells

por Sotcheff, Stephanea L., Chen, John Yun-Chung, Elrod, Nathan, Cao, Jun, Jaworski, Elizabeth, Kuyumcu-Martinez, Mugé N., Shi, Pei-Yong, Routh, Andrew L.
Publicado 2022

The Integrator complex cleaves nascent mRNAs to attenuate transcription

por Tatomer, Deirdre C., Elrod, Nathan D., Liang, Dongming, Xiao, Mei-Sheng, Jiang, Jeffrey Z., Jonathan, Michael, Huang, Kai-Lieh, Wagner, Eric J., Cherry, Sara, Wilusz, Jeremy E.
Publicado 2019

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome

por Enwerem, Isioma I.I., Elrod, Nathan D., Chang, Chung-Te, Lin, Ai, Ji, Ping, Bohn, Jennifer A., Levdansky, Yevgen, Wagner, Eric J., Valkov, Eugene, Goldstrohm, Aaron C.
Publicado 2021

Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase

por Haugen, Rebecca J., Barnier, Catherine, Elrod, Nathan D., Luo, Hua, Jensen, Madeline K., Ji, Ping, Smibert, Craig A., Lipshitz, Howard D., Wagner, Eric J., Lydia Freddolino, P., Goldstrohm, Aaron C.
Publicado 2023

Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation

por Alcott, Callison E, Yalamanchili, Hari Krishna, Ji, Ping, van der Heijden, Meike E, Saltzman, Alexander, Elrod, Nathan, Lin, Ai, Leng, Mei, Bhatt, Bhoomi, Hao, Shuang, Wang, Qi, Saliba, Afaf, Tang, Jianrong, Malovannaya, Anna, Wagner, Eric J, Liu, Zhandong, Zoghbi, Huda Y
Publicado 2020

RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts

por Cao, Jun, Verma, Sunil K., Jaworski, Elizabeth, Mohan, Stephanie, Nagasawa, Chloe K., Rayavara, Kempaiah, Sooter, Amanda, Miller, Sierra N., Holcomb, Richard J., Powell, Mason J., Ji, Ping, Elrod, Nathan D., Yildirim, Eda, Wagner, Eric J., Popov, Vsevolod, Garg, Nisha J., Routh, Andrew L., Kuyumcu-Martinez, Muge N.
Publicado 2021

Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis

por Wilson, Cory, Mertens, Tinne C.J., Shivshankar, Pooja, Bi, Weizen, Collum, Scott D., Wareing, Nancy, Ko, Junsuk, Weng, Tingting, Naikawadi, Ram P., Wolters, Paul J., Maire, Pascal, Jyothula, Soma S.K., Thandavarayan, Rajarajan A., Ren, Dewei, Elrod, Nathan D., Wagner, Eric J., Huang, Howard J., Dickey, Burton F., Ford, Heide L., Karmouty-Quintana, Harry
Publicado 2022

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex

por Mascibroda, Lauren G., Shboul, Mohammad, Elrod, Nathan D., Colleaux, Laurence, Hamamy, Hanan, Huang, Kai-Lieh, Peart, Natoya, Singh, Moirangthem Kiran, Lee, Hane, Merriman, Barry, Jodoin, Jeanne N., Sitaram, Poojitha, Lee, Laura A., Fathalla, Raja, Al-Rawashdeh, Baeth, Ababneh, Osama, El-Khateeb, Mohammad, Escande-Beillard, Nathalie, Nelson, Stanley F., Wu, Yixuan, Tong, Liang, Kenney, Linda J., Roy, Sudipto, Russell, William K., Amiel, Jeanne, Reversade, Bruno, Wagner, Eric J.
Publicado 2022

Alternative polyadenylation alters protein dosage by switching between intronic and 3′UTR sites

por de Prisco, Nicola, Ford, Caitlin, Elrod, Nathan D., Lee, Winston, Tang, Lauren C., Huang, Kai-Lieh, Lin, Ai, Ji, Ping, Jonnakuti, Venkata S., Boyle, Lia, Cabaj, Maximilian, Botta, Salvatore, Õunap, Katrin, Reinson, Karit, Wojcik, Monica H., Rosenfeld, Jill A., Bi, Weimin, Tveten, Kristian, Prescott, Trine, Gerstner, Thorsten, Schroeder, Audrey, Fong, Chin-To, George-Abraham, Jaya K., Buchanan, Catherine A., Hanson-Khan, Andrea, Bernstein, Jonathan A., Nella, Aikaterini A., Chung, Wendy K., Brandt, Vicky, Jovanovic, Marko, Targoff, Kimara L., Yalamanchili, Hari Krishna, Wagner, Eric J., Gennarino, Vincenzo A.
Publicado 2023