Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors

por Elsayed, Zainab M., Almahli, Hadia, Nocentini, Alessio, Ammara, Andrea, Supuran, Claudiu T., Eldehna, Wagdy M., Abou-Seri, Sahar M.
Publicado 2023

Development of Novel Quinoline-Based Sulfonamides as Selective Cancer-Associated Carbonic Anhydrase Isoform IX Inhibitors

por Shaldam, Moataz, Nocentini, Alessio, Elsayed, Zainab M., Ibrahim, Tamer M., Salem, Rofaida, El-Domany, Ramadan A., Capasso, Clemente, Supuran, Claudiu T., Eldehna, Wagdy M.
Publicado 2021

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibi...

por Eldehna, Wagdy M., El Hassab, Mahmoud A., Elsayed, Zainab M., Al-Warhi, Tarfah, Elkady, Hazem, Abo-Ashour, Mahmoud F., Abourehab, Mohammed A. S., Eissa, Ibrahim H., Abdel-Aziz, Hatem A.
Publicado 2022

Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights

por Al-Warhi, Tarfah, El Kerdawy, Ahmed M, Said, Mohamed A, Albohy, Amgad, Elsayed, Zainab M, Aljaeed, Nada, Elkaeed, Eslam B, Eldehna, Wagdy M, Abdel-Aziz, Hatem A, Abdelmoaz, Miral A
Publicado 2022

Development of novel isatin–nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing–bacteria

por Elsayed, Zainab M., Eldehna, Wagdy M., Abdel-Aziz, Marwa M., El Hassab, Mahmoud A., Elkaeed, Eslam B., Al-Warhi, Tarfah, Abdel-Aziz, Hatem A., Abou-Seri, Sahar M., Mohammed, Eman R.
Publicado 2021

Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer

por Eldehna, Wagdy M., Salem, Rofaida, Elsayed, Zainab M., Al-Warhi, Tarfah, Knany, Hamada R., Ayyad, Rezk R., Traiki, Thamer Bin, Abdulla, Maha-Hamadien, Ahmad, Rehan, Abdel-Aziz, Hatem A., El-Haggar, Radwan
Publicado 2021

Development of novel isatin thiazolyl-pyrazoline hybrids as promising antimicrobials in MDR pathogens

por Al-Warhi, Tarfah, Elimam, Diaaeldin M., Elsayed, Zainab M., Abdel-Aziz, Marwa M., Maklad, Raed M., Al-Karmalawy, Ahmed A., Afarinkia, Kamyar, Abourehab, Mohammed A. S., Abdel-Aziz, Hatem A., Eldehna, Wagdy M.
Publicado 2022

1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights

por Al-Warhi, Tarfah, Almahli, Hadia, Maklad, Raed M., Elsayed, Zainab M., El Hassab, Mahmoud A., Alotaibi, Ohoud J., Aljaeed, Nada, Ayyad, Rezk R., Ghabour, Hazem A., Eldehna, Wagdy M., El-Ashrey, Mohamed K.
Publicado 2023

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors

por Shaldam, Moataz A., Almahli, Hadia, Angeli, Andrea, Badi, Rehab Mustafa, Khaleel, Eman F., Zain-Alabdeen, Abdelrahman I., Elsayed, Zainab M., Elkaeed, Eslam B., Salem, Rofaida, Supuran, Claudiu T., Eldehna, Wagdy M., Tawfik, Haytham O.
Publicado 2023

Development of 3-methyl/3-(morpholinomethyl)benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells

por Al-Sanea, Mohammad M., Al-Ansary, Ghada H., Elsayed, Zainab M., Maklad, Raed M., Elkaeed, Eslam B., Abdelgawad, Mohamed A., Bukhari, Syed Nasir Abbas, Abdel-Aziz, Marwa M., Suliman, Howayda, Eldehna, Wagdy M.
Publicado 2021

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

por Al-Sanea, Mohammad M, Gotina, Lizaveta, Mohamed, Mamdouh FA, Grace Thomas Parambi, Della, Gomaa, Hesham A M, Mathew, Bijo, Youssif, Bahaa G M, Alharbi, Khalid Saad, Elsayed, Zainab M, Abdelgawad, Mohamed A, Eldehna, Wagdy M
Publicado 2020

Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease

por ElNaggar, Mai H., Elgazar, Abdullah A., Gamal, Ghada, Hamed, Shimaa M., Elsayed, Zainab M., El-Ashrey, Mohamed K., Abood, Amira, El Hassab, Mahmoud A., Soliman, Ahmed M., El-Domany, Ramadan A., Badria, Farid A., Supuran, Claudiu T., Eldehna, Wagdy M.
Publicado 2023