Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury

por Hu, Daniel Jun-Kit, Yun, Jina, Elstrott, Justin, Jasper, Heinrich
Publicado 2021

Integration of human stem cell-derived in vitro systems and mouse preclinical models identifies complex pathophysiologic mechanisms in retinal dystrophy

por Jones, Melissa K., Orozco, Luz D., Qin, Han, Truong, Tom, Caplazi, Patrick, Elstrott, Justin, Modrusan, Zora, Chaney, Shawnta Y., Jeanne, Marion
Publicado 2023

Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants

por Bien-Ly, Nga, Yu, Y. Joy, Bumbaca, Daniela, Elstrott, Justin, Boswell, C. Andrew, Zhang, Yin, Luk, Wilman, Lu, Yanmei, Dennis, Mark S., Weimer, Robby M., Chung, Inhee, Watts, Ryan J.
Publicado 2014

Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

por Katschke, Kenneth J., Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P., McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M, van Lookeren Campagne, Menno
Publicado 2018

Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

por Katschke, Kenneth J., Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P., McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M., van Lookeren Campagne, Menno
Publicado 2018

IL-33 amplifies an innate immune response in the degenerating retina

por Xi, Hongkang, Katschke, Kenneth J., Li, Yun, Truong, Tom, Lee, Wyne P., Diehl, Lauri, Rangell, Linda, Tao, Jianhua, Arceo, Rommel, Eastham-Anderson, Jeffrey, Hackney, Jason A., Iglesias, Antonio, Cote-Sierra, Javier, Elstrott, Justin, Weimer, Robby M., van Lookeren Campagne, Menno
Publicado 2016

Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mou...

por Meilandt, William J., Ngu, Hai, Gogineni, Alvin, Lalehzadeh, Guita, Lee, Seung-Hye, Srinivasan, Karpagam, Imperio, Jose, Wu, Tiffany, Weber, Martin, Kruse, Agatha J., Stark, Kimberly L., Chan, Pamela, Kwong, Mandy, Modrusan, Zora, Friedman, Brad A., Elstrott, Justin, Foreman, Oded, Easton, Amy, Sheng, Morgan, Hansen, David V.
Publicado 2020

Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease

por Dai, Bingbing, Hackney, Jason A., Ichikawa, Ryan, Nguyen, Allen, Elstrott, Justin, Orozco, Luz D., Sun, Kai-Hui, Modrusan, Zora, Gogineni, Alvin, Scherl, Alexis, Gubatan, John, Habtezion, Aida, Deswal, Monika, Somsouk, Ma, Faubion, William A., Chai, Akiko, Sharafali, Zaineb, Hassanali, Azra, Oh, Young S., Tole, Swati, McBride, Jacqueline, Keir, Mary E., Yi, Tangsheng
Publicado 2021

GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models

por Hanson, Jesse E., Ma, Keran, Elstrott, Justin, Weber, Martin, Saillet, Sandrine, Khan, Abdullah S., Simms, Jeffrey, Liu, Benjamin, Kim, Thomas A., Yu, Gui-Qiu, Chen, Yelin, Wang, Tzu-Ming, Jiang, Zhiyu, Liederer, Bianca M., Deshmukh, Gauri, Solanoy, Hilda, Chan, Connie, Sellers, Benjamin D., Volgraf, Matthew, Schwarz, Jacob B., Hackos, David H., Weimer, Robby M., Sheng, Morgan, Gill, T. Michael, Scearce-Levie, Kimberly, Palop, Jorge J.
Publicado 2020

Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors

por Castiglioni, Alessandra, Yang, Yagai, Williams, Katherine, Gogineni, Alvin, Lane, Ryan S., Wang, Amber W., Shyer, Justin A., Zhang, Zhe, Mittman, Stephanie, Gutierrez, Alan, Astarita, Jillian L., Thai, Minh, Hung, Jeffrey, Yang, Yeqing Angela, Pourmohamad, Tony, Himmels, Patricia, De Simone, Marco, Elstrott, Justin, Capietto, Aude-Hélène, Cubas, Rafael, Modrusan, Zora, Sandoval, Wendy, Ziai, James, Gould, Stephen E., Fu, Wenxian, Wang, Yulei, Koerber, James T., Sanjabi, Shomyseh, Mellman, Ira, Turley, Shannon J., Müller, Sören
Publicado 2023

LRRC15(+) myofibroblasts dictate the stromal setpoint to suppress tumour immunity

por Krishnamurty, Akshay T., Shyer, Justin A., Thai, Minh, Gandham, Vineela, Buechler, Matthew B., Yang, Yeqing Angela, Pradhan, Rachana N., Wang, Amber W., Sanchez, Patricia L., Qu, Yan, Breart, Beatrice, Chalouni, Cécile, Dunlap, Debra, Ziai, James, Elstrott, Justin, Zacharias, Neelie, Mao, Weiguang, Rowntree, Rebecca K., Sadowsky, Jack, Lewis, Gail D., Pillow, Thomas H., Nabet, Barzin Y., Banchereau, Romain, Tam, Lucinda, Caothien, Roger, Bacarro, Natasha, Roose-Girma, Merone, Modrusan, Zora, Mariathasan, Sanjeev, Müller, Sören, Turley, Shannon J.
Publicado 2022

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

por Balestrini, Alessia, Joseph, Victory, Dourado, Michelle, Reese, Rebecca M., Shields, Shannon D., Rougé, Lionel, Bravo, Daniel D., Chernov-Rogan, Tania, Austin, Cary D., Chen, Huifen, Wang, Lan, Villemure, Elisia, Shore, Daniel G.M., Verma, Vishal A., Hu, Baihua, Chen, Yong, Leong, Laurie, Bjornson, Chris, Hötzel, Kathy, Gogineni, Alvin, Lee, Wyne P., Suto, Eric, Wu, Xiumin, Liu, John, Zhang, Juan, Gandham, Vineela, Wang, Jianyong, Payandeh, Jian, Ciferri, Claudio, Estevez, Alberto, Arthur, Christopher P., Kortmann, Jens, Wong, Ryan L., Heredia, Jose E., Doerr, Jonas, Jung, Min, Vander Heiden, Jason A., Roose-Girma, Merone, Tam, Lucinda, Barck, Kai H., Carano, Richard A.D., Ding, Han Ting, Brillantes, Bobby, Tam, Christine, Yang, Xiaoying, Gao, Simon S., Ly, Justin Q., Liu, Liling, Chen, Liuxi, Liederer, Bianca M., Lin, Joseph H., Magnuson, Steven, Chen, Jun, Hackos, David H., Elstrott, Justin, Rohou, Alexis, Safina, Brian S., Volgraf, Matthew, Bauer, Rebecca N., Riol-Blanco, Lorena
Publicado 2021