Mucormycosis in South America: A review of 143 reported cases

por Nucci, Marcio, Engelhardt, Marc, Hamed, Kamal
Publicado 2019

1149. Baseline Chest CT Findings in Patients with Pulmonary Mold Infections: A Post-Hoc Analysis from the Phase 3 SECURE Study that Compared Isavuconazole to Voriconazole for the P...

por Hamed, Kamal, Engelhardt, Marc, Saulay, Mikael, Kovanda, Laura
Publicado 2020

A randomized double-blind placebo-controlled trial to investigate the effects of nasal calcitonin on bone microarchitecture measured by high-resolution peripheral quantitative comp...

por Richert, Laura, Uebelhart, Brigitte, Engelhardt, Marc, Azria, Moise, Rizzoli, René
Publicado 2008

Variability and exposure–response relationships of isavuconazole plasma concentrations in the Phase 3 SECURE trial of patients with invasive mould diseases

por Kaindl, Thomas, Andes, David, Engelhardt, Marc, Saulay, Mikael, Larger, Patrice, Groll, Andreas H
Publicado 2019

Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies

por Hamed, Kamal, Engelhardt, Marc, Kovanda, Laura L., Huang, Jin Ju, Yan, Jean, Aram, Jalal A.
Publicado 2023

Early improvement in severely ill patients with pneumonia treated with ceftobiprole: a retrospective analysis of two major trials

por Scheeren, Thomas W. L., Welte, Tobias, Saulay, Mikael, Engelhardt, Marc, Santerre-Henriksen, Anne, Hamed, Kamal
Publicado 2019

Ceftobiprole versus daptomycin in Staphylococcus aureus bacteremia: a novel protocol for a double-blind, Phase III trial

por Hamed, Kamal, Engelhardt, Marc, Jones, Mark E, Saulay, Mikael, Holland, Thomas L, Seifert, Harald, Fowler Jr, Vance G
Publicado 2020

Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole

por Kovanda, Laura L., Marty, Francisco M., Maertens, Johan, Desai, Amit V., Lademacher, Christopher, Engelhardt, Marc, Lu, Qiaoyang, Hope, William W.
Publicado 2017

2561. Population Pharmacokinetic Analyses for Ceftobiprole Using Data from Phase 1 and 3 Studies

por Cammarata, Anthony P, Litherland, Karine, Safir, M Courtney, Bhavnani, Sujata M, Saulay, Mikael, Smart, Jennifer, Jones, Mark E, Engelhardt, Marc, Rubino, Christopher M
Publicado 2023

Safety and anti-tumor activity of lisavanbulin administered as 48-hour infusion in patients with ovarian cancer or recurrent glioblastoma: a phase 2a study

por Joerger, Markus, Hundsberger, Thomas, Haefliger, Simon, von Moos, Roger, Hottinger, Andreas F., Kaindl, Thomas, Engelhardt, Marc, Marszewska, Michalina, Lane, Heidi, Roth, Patrick, Stathis, Anastasios
Publicado 2023

2785. Characterization of Methicillin-resistant Staphylococcus aureus Bloodstream Isolates Recovered from Patients Enrolled in a Randomized, Double-blind, Multi-center Study to Est...

por Mendes, Rodrigo E, Duncan, Leonard R, Kimbrough, John H, Holland, Thomas L, Fowler, Vance G, Jones, Mark E, Engelhardt, Marc, Smart, Jennifer, Castanheira, Mariana
Publicado 2023

Principles and Applications of CF(2)X Moieties as Unconventional Halogen Bond Donors in Medicinal Chemistry, Chemical Biology, and Drug Discovery

por Vaas, Sebastian, Zimmermann, Markus O., Schollmeyer, Dieter, Stahlecker, Jason, Engelhardt, Marc U., Rheinganz, Janosch, Drotleff, Bernhard, Olfert, Matthias, Lämmerhofer, Michael, Kramer, Markus, Stehle, Thilo, Boeckler, Frank M.
Publicado 2023

2530. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Ceftobiprole Dose Selection for the Treatment of Patients with Acute Bacterial Skin and Skin Str...

por Bhavnani, Sujata M, Hammel, Jeffrey P, Rinaldo, Anthony J, Smart, Jennifer, Litherland, Karine, Duncan, Leonard R, Jones, Mark E, Engelhardt, Marc, Ambrose, Paul G, Rubino, Christopher M
Publicado 2023

2531. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Ceftobiprole Dosing Regimens for Patients with Staphylococcus aureus Bacteremia (SAB)

por Bhavnani, Sujata M, Hammel, Jeffrey P, Rinaldo, Anthony J, Smart, Jennifer, Litherland, Karine, Duncan, Leonard R, Jones, Mark E, Engelhardt, Marc, Ambrose, Paul G, Rubino, Christopher M
Publicado 2023

2532. Pharmacokinetic-Pharmacodynamic Analyses for Ceftobiprole Efficacy Based on Phase 3 Data from Patients with Staphylococcus aureus Bacteremia

por Bhavnani, Sujata M, Hammel, Jeffrey P, Liolios, Kathryn, Cammarata, Anthony P, Saulay, Mikael, Rubino, Christopher M, Engelhardt, Marc, Smart, Jennifer, Jones, Mark E, Ambrose, Paul G, Litherland, Karine
Publicado 2023

Isavuconazole treatment for rare fungal diseases and for invasive aspergillosis in patients with renal impairment: Challenges and lessons of the VITAL trial

por Perfect, John R., Cornely, Oliver A., Heep, Markus, Ostrosky-Zeichner, Luis, Mullane, Kathleen M., Maher, Rochelle, Croos-Dabrera, Rodney, Lademacher, Christopher, Engelhardt, Marc, Chen, Caroline, Marty, Francisco M.
Publicado 2018

Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling

por Woodhead, Jeffrey L., Paech, Franziska, Maurer, Martina, Engelhardt, Marc, Schmitt‐Hoffmann, Anne H., Spickermann, Jochen, Messner, Simon, Wind, Mathias, Witschi, Anne‐Therese, Krähenbühl, Stephan, Siler, Scott Q., Watkins, Paul B., Howell, Brett A.
Publicado 2018

A Phase 1 study of BAL101553, a novel tumor checkpoint controller targeting microtubules, administered as 48-h infusion in adult patients with advanced solid tumors

por Joerger, Markus, Stathis, Anastasios, Metaxas, Yannis, Hess, Dagmar, Mantiero, Mara, Mark, Michael, Volden, Matthias, Kaindl, Thomas, Engelhardt, Marc, Larger, Patrice, Lane, Heidi, Hafner, Peter, Levy, Nicole, Stuedeli, Silvia, Sessa, Cristiana, von Moos, Roger
Publicado 2019

Ceftobiprole Compared With Vancomycin Plus Aztreonam in the Treatment of Acute Bacterial Skin and Skin Structure Infections: Results of a Phase 3, Randomized, Double-blind Trial (T...

por Overcash, J Scott, Kim, Charles, Keech, Richard, Gumenchuk, Illia, Ninov, Borislav, Gonzalez-Rojas, Yaneicy, Waters, Michael, Simeonov, Simeon, Engelhardt, Marc, Saulay, Mikael, Ionescu, Daniel, Smart, Jennifer I, Jones, Mark E, Hamed, Kamal A
Publicado 2020

Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses

por Thompson, George R., Rendon, Adrian, Ribeiro dos Santos, Rodrigo, Queiroz-Telles, Flavio, Ostrosky-Zeichner, Luis, Azie, Nkechi, Maher, Rochelle, Lee, Misun, Kovanda, Laura, Engelhardt, Marc, Vazquez, Jose A., Cornely, Oliver A., Perfect, John R.
Publicado 2016