pHLIP and Acidity as a Universal Biomarker for Cancer

por Fendos, Justin, Engelman, Donald
Publicado 2012

CURRENT MODELS FOR THE STRUCTURE OF BIOLOGICAL MEMBRANES

por Stoeckenius, Walther, Engelman, Donald M.
Publicado 1969

Helix-helix interactions inside lipid bilayers

por Lemmon, Mark A., Engelman, Donald M.
Publicado 1992

Pharmacokinetic modeling reveals parameters that govern tumor targeting and delivery by a pH-Low Insertion Peptide (pHLIP)

por Svoronos, Alexander A., Engelman, Donald M.
Publicado 2021

Genomic analysis of membrane protein families: abundance and conserved motifs

por Liu, Yang, Engelman, Donald M, Gerstein, Mark
Publicado 2002

Targeting diseased tissues by pHLIP insertion at low cell surface pH

por Andreev, Oleg A., Engelman, Donald M., Reshetnyak, Yana K.
Publicado 2014

MicroRNA function can be reversed by altering target gene expression levels

por Svoronos, Alexander A., Campbell, Stuart G., Engelman, Donald M.
Publicado 2021

Accurate Analysis of Tumor Margins Using a Fluorescent pH Low Insertion Peptide (pHLIP)

por Segala, James, Engelman, Donald M., Reshetnyak, Yana K., Andreev, Oleg A.
Publicado 2009

Targeting Acidic Diseased Tissues by pH-Triggered Membrane-Associated Peptide Folding

por Reshetnyak, Yana K., Moshnikova, Anna, Andreev, Oleg A., Engelman, Donald M.
Publicado 2020

The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein

por Miyauchi, Kosuke, Curran, A Rachael, Long, Yufei, Kondo, Naoyuki, Iwamoto, Aikichi, Engelman, Donald M, Matsuda, Zene
Publicado 2010

Eradication of tumors and development of anti-cancer immunity using STINGa targeted by pHLIP

por Moshnikova, Anna, DuPont, Michael, Visca, Hannah, Engelman, Donald M., Andreev, Oleg A., Reshetnyak, Yana K.
Publicado 2022

Tumor treatment by pHLIP-targeted antigen delivery

por DuPont, Michael, Visca, Hannah, Moshnikova, Anna, Engelman, Donald M., Reshetnyak, Yana K., Andreev, Oleg A.
Publicado 2023

Mapping the Homodimer Interface of an Optimized, Artificial, Transmembrane Protein Activator of the Human Erythropoietin Receptor

por Cohen, Emily B., Jun, Susan J., Bears, Zachary, Barrera, Francisco N., Alonso, Miriam, Engelman, Donald M., DiMaio, Daniel
Publicado 2014

pHLIP-FIRE, a Cell Insertion-Triggered Fluorescent Probe for Imaging Tumors Demonstrates Targeted Cargo Delivery In Vivo

por Karabadzhak, Alexander G., An, Ming, Yao, Lan, Langenbacher, Rachel, Moshnikova, Anna, Adochite, Ramona-Cosmina, Andreev, Oleg A., Reshetnyak, Yana K., Engelman, Donald M.
Publicado 2014

pHLIP ICG for delineation of tumors and blood flow during fluorescence-guided surgery

por Crawford, Troy, Moshnikova, Anna, Roles, Sean, Weerakkody, Dhammika, DuPont, Michael, Carter, Lukas M., Shen, John, Engelman, Donald M., Lewis, Jason S., Andreev, Oleg A., Reshetnyak, Yana K.
Publicado 2020

MicroRNA silencing for cancer therapy targeted to the tumor microenvironment

por Cheng, Christopher J., Bahal, Raman, Babar, Imran A., Pincus, Zachary, Barrera, Francisco, Liu, Connie, Svoronos, Alexander, Braddock, Demetrios T., Glazer, Peter M., Engelman, Donald M., Saltzman, W. Mark, Slack, Frank J.
Publicado 2014

Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy

por Liu, Wu, Deacon, John, Yan, Huagang, Sun, Bo, Liu, Yanfeng, Hegan, Denise, Li, Qin, Coman, Daniel, Parent, Maxime, Hyder, Fahmeed, Roberts, Kenneth, Nath, Ravinder, Tillement, Olivier, Engelman, Donald, Glazer, Peter
Publicado 2020

PET Imaging of Extracellular pH in Tumors with (64)Cu- and (18)F-Labeled pHLIP Peptides: A Structure–Activity Optimization Study

por Demoin, Dustin Wayne, Wyatt, Linden C., Edwards, Kimberly J., Abdel-Atti, Dalya, Sarparanta, Mirkka, Pourat, Jacob, Longo, Valerie A., Carlin, Sean D., Engelman, Donald M., Andreev, Oleg A., Reshetnyak, Yana K., Viola-Villegas, Nerissa, Lewis, Jason S.
Publicado 2016

Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity

por Gayle, Sophia, Aiello, Robert, Leelatian, Nalin, Beckta, Jason M, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Maguire, Robert J, Marshall, Dan, Sundaram, Ranjini K, Van Doorn, Jinny, Jones, Kelli, Moore, Hunter, Lopresti-Morrow, Lori, Paradis, Timothy, Tylaska, Laurie, Zhang, Qing, Visca, Hannah, Reshetnyak, Yana K, Andreev, Oleg A, Engelman, Donald M, Glazer, Peter M, Bindra, Ranjit S, Paralkar, Vishwas M
Publicado 2021

Correction to ‘Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity’

por Gayle, Sophia, Aiello, Robert, Leelatian, Nalin, Beckta, Jason M, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Maguire, Robert J, Marshall, Dan, Sundaram, Ranjini K, Van Doorn, Jinny, Jones, Kelli, Moore, Hunter, Lopresti-Morrow, Lori, Paradis, Timothy, Tylaska, Laurie, Zhang, Qing, Visca, Hannah, Reshetnyak, Yana K, Andreev, Oleg A, Engelman, Donald M, Glazer, Peter M, Bindra, Ranjit S, Paralkar, Vishwas M
Publicado 2021