MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to loss of the HES1/Notch1 regulatory circuit

por Spitschak, Alf, Meier, Claudia, Kowtharapu, Bhavani, Engelmann, David, Pützer, Brigitte M.
Publicado 2017

E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry

por Alla, Vijay, Kowtharapu, Bhavani S., Engelmann, David, Emmrich, Stephan, Schmitz, Ulf, Steder, Marc, Pützer, Brigitte M.
Publicado 2012

Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures

por Wang, Yajie, Alla, Vijay, Goody, Deborah, Gupta, Shailendra K., Spitschak, Alf, Wolkenhauer, Olaf, Pützer, Brigitte M., Engelmann, David
Publicado 2016

Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

por Khan, Faiz M., Marquardt, Stephan, Gupta, Shailendra K., Knoll, Susanne, Schmitz, Ulf, Spitschak, Alf, Engelmann, David, Vera, Julio, Wolkenhauer, Olaf, Pützer, Brigitte M.
Publicado 2017

LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1

por Logotheti, Stella, Marquardt, Stephan, Gupta, Shailendra K., Richter, Christin, Edelhäuser, Berdien A.H., Engelmann, David, Brenmoehl, Julia, Söhnchen, Christoph, Murr, Nico, Alpers, Michael, Singh, Krishna P., Wolkenhauer, Olaf, Heckl, Dirk, Spitschak, Alf, Pützer, Brigitte M.
Publicado 2020

Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers

por Goody, Deborah, Gupta, Shailendra K., Engelmann, David, Spitschak, Alf, Marquardt, Stephan, Mikkat, Stefan, Meier, Claudia, Hauser, Charlotte, Gundlach, Jan-Paul, Egberts, Jan-Hendrik, Martin, Hubert, Schumacher, Toni, Trauzold, Anna, Wolkenhauer, Olaf, Logotheti, Stella, Pützer, Brigitte M.
Publicado 2019