Applications of Hydrogen/Deuterium Exchange MS from 2012 to 2014

por Pirrone, Gregory F., Iacob, Roxana E., Engen, John R.
Publicado 2014

Allosteric Interactions between the Myristate- and ATP-Site of the Abl Kinase

por Iacob, Roxana E., Zhang, Jianming, Gray, Nathanael S., Engen, John R.
Publicado 2011

Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding

por Kardon, Julia R, Moroco, Jamie A, Engen, John R, Baker, Tania A
Publicado 2020

General structural features that regulate integrin affinity revealed by atypical αVβ8

por Wang, Jianchuan, Su, Yang, Iacob, Roxana E., Engen, John R., Springer, Timothy A.
Publicado 2019

Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems

por James, Ellie I., Murphree, Taylor A., Vorauer, Clint, Engen, John R., Guttman, Miklos
Publicado 2021

Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change

por Su, Yang, Iacob, Roxana E., Li, Jing, Engen, John R., Springer, Timothy A.
Publicado 2022

Electron Transfer Control in Soluble Methane Monooxygenase

por Wang, Weixue, Iacob, Roxana E., Luoh, Rebecca P., Engen, John R., Lippard, Stephen J.
Publicado 2014

Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

por Cohen, Daniel T., Wales, Thomas E., McHenry, Matthew W., Engen, John R., Walensky, Loren D.
Publicado 2020

A redox switch regulates the structure and function of anti-apoptotic BFL-1

por Korshavn, Kyle J., Wales, Thomas E., Bird, Gregory H., Engen, John R., Walensky, Loren D.
Publicado 2020

Differential impact of BTK active site inhibitors on the conformational state of full-length BTK

por Joseph, Raji E, Amatya, Neha, Fulton, D Bruce, Engen, John R, Wales, Thomas E, Andreotti, Amy
Publicado 2020

c-Abl Tyrosine Kinase Adopts Multiple Active Conformational States in Solution

por Badger, John, Grover, Prerna, Shi, Haibin, Panjarian, Shoghag B., Engen, John R., Smithgall, Thomas E., Makowski, Lee
Publicado 2016

The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core

por Bloch, Noah B., Wales, Thomas E., Prew, Michelle S., Levy, Hannah R., Engen, John R., Walensky, Loren D.
Publicado 2021

A Conformational Investigation of Propeptide Binding to the Integral Membrane Protein γ-Glutamyl Carboxylase Using Nanodisc Hydrogen Exchange Mass Spectrometry

por Parker, Christine H., Morgan, Christopher R., Rand, Kasper D., Engen, John R., Jorgenson, James W., Stafford, Darrel W.
Publicado 2014

Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement

por Moroco, Jamie A., Craigo, Jodi K., Iacob, Roxana E., Wales, Thomas E., Engen, John R., Smithgall, Thomas E.
Publicado 2014

Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker

por Bonazza, Klaus, Iacob, Roxana E, Hudson, Nathan E, Li, Jing, Lu, Chafen, Engen, John R, Springer, Timothy A
Publicado 2022

Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases

por Chopra, Nikita, Wales, Thomas E., Joseph, Raji E., Boyken, Scott E., Engen, John R., Jernigan, Robert L., Andreotti, Amy H.
Publicado 2016

Design of Stapled Antimicrobial Peptides that Overcome Antibiotic Resistance and In Vivo Toxicity

por Mourtada, Rida, Herce, Henry D., Yin, Daniel J., Moroco, Jamie A., Wales, Thomas E., Engen, John R., Walensky, Loren D.
Publicado 2019

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly

por Chaikuad, Apirat, Filippakopoulos, Panagis, Marcsisin, Sean R., Picaud, Sarah, Schröder, Martin, Sekine, Shiori, Ichijo, Hidenori, Engen, John R., Takeda, Kohsuke, Knapp, Stefan
Publicado 2017

Fusion surface structure, function, and dynamics of gamete fusogen HAP2

por Feng, Juan, Dong, Xianchi, Pinello, Jennifer, Zhang, Jun, Lu, Chafen, Iacob, Roxana E, Engen, John R, Snell, William J, Springer, Timothy A
Publicado 2018

Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4

por Bodnar, Nicholas O., Kim, Kelly H., Ji, Zhejian, Wales, Thomas E., Svetlov, Vladimir, Nudler, Evgeny, Engen, John R., Walz, Thomas, Rapoport, Tom A.
Publicado 2018