Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

por Tse, Justin R., Engler, Adam J.
Publicado 2011

Rationally engineered advances in cancer research

por Engler, Adam J., Discher, Dennis E.
Publicado 2018

Cation Type Specific Cell Remodeling Regulates Attachment Strength

por Fuhrmann, Alexander, Li, Julie, Chien, Shu, Engler, Adam J.
Publicado 2014

Recent advancements and future requirements in vascularization of cortical organoids

por LaMontagne, Erin, Muotri, Alysson R., Engler, Adam J.
Publicado 2022

Computational models of migration modes improve our understanding of metastasis

por Shatkin, Gabriel, Yeoman, Benjamin, Birmingham, Katherine, Katira, Parag, Engler, Adam J.
Publicado 2020

Adhesion strength and contractility enable metastatic cells to become adurotactic

por Yeoman, Benjamin, Shatkin, Gabriel, Beri, Pranjali, Banisadr, Afsheen, Katira, Parag, Engler, Adam J.
Publicado 2021

Mechanosensitive Kinases Regulate Stiffness-Induced Cardiomyocyte Maturation

por Young, Jennifer L., Kretchmer, Kyle, Ondeck, Matthew G., Zambon, Alexander C., Engler, Adam J.
Publicado 2014

Mechanical regulation of cardiac fibroblast profibrotic phenotypes

por Herum, Kate M., Choppe, Jonas, Kumar, Aditya, Engler, Adam J., McCulloch, Andrew D.
Publicado 2017

Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation

por Happe, Cassandra L., Tenerelli, Kevin P., Gromova, Anastasia K., Kolb, Frederic, Engler, Adam J.
Publicado 2017

Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

por Joshi-Barr, Shivanjali, Karpiak, Jerome V., Ner, Yogesh, Wen, Jessica H., Engler, Adam J., Almutairi, Adah
Publicado 2013

Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments

por Engler, Adam J., Griffin, Maureen A., Sen, Shamik, Bönnemann, Carsten G., Sweeney, H. Lee, Discher, Dennis E.
Publicado 2004

Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction

por Kaushik, Gaurav, Zambon, Alexander C, Fuhrmann, Alexander, Bernstein, Sanford I, Bodmer, Rolf, Engler, Adam J, Cammarato, Anthony, Mercola, Mark
Publicado 2012

Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age‐associated functional decline

por Blice‐Baum, Anna C., Zambon, Alexander C., Kaushik, Gaurav, Viswanathan, Meera C., Engler, Adam J., Bodmer, Rolf, Cammarato, Anthony
Publicado 2017

Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity

por Mayner, Jaimie M., Masutani, Evan M., Demeester, Elena, Kumar, Aditya, Macapugay, Gail, Beri, Pranjali, Lo Sardo, Valentina, Engler, Adam J.
Publicado 2023

YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis

por Wu, Zhengming, Su, Junhui, Li, Fu-long, Chen, Tao, Mayner, Jaimie, Engler, Adam, Ma, Shenghong, Li, Qingquan, Guan, Kun-Liang
Publicado 2023

Multi-scale cellular engineering: From molecules to organ-on-a-chip

por Huang, Ngan F., Chaudhuri, Ovijit, Cahan, Patrick, Wang, Aijun, Engler, Adam J., Wang, Yingxiao, Kumar, Sanjay, Khademhosseini, Ali, Li, Song
Publicado 2020

Spatial transcriptomics tools allow for regional exploration of heterogeneous muscle pathology in the pre-clinical rabbit model of rotator cuff tear

por Ruoss, Severin, Esparza, Mary C., Vasquez-Bolanos, Laura S., Nasamran, Chanond A., Fisch, Kathleen M., Engler, Adam J., Ward, Samuel R.
Publicado 2022

Interplay of Matrix Stiffness and Protein Tethering in Stem Cell Differentiation

por Wen, Jessica H., Vincent, Ludovic G., Fuhrmann, Alexander, Choi, Yu Suk, Hribar, Kolin, Taylor-Weiner, Hermes, Chen, Shaochen, Engler, Adam J.
Publicado 2014

Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span

por Sessions, Ayla O., Min, Peter, Cordes, Thekla, Weickert, Barry J., Divakaruni, Ajit S., Murphy, Anne N., Metallo, Christian M., Engler, Adam J.
Publicado 2018

Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy

por Powers, Joseph D., Kirkland, Natalie J., Liu, Canzhao, Razu, Swithin S., Fang, Xi, Engler, Adam J., Chen, Ju, McCulloch, Andrew D.
Publicado 2022