Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease

por Engreitz, Jesse M., Agarwala, Vineeta, Mirny, Leonid A.
Publicado 2012

Positional specificity of different transcription factor classes within enhancers

por Grossman, Sharon R., Engreitz, Jesse, Ray, John P., Nguyen, Tung H., Hacohen, Nir, Lander, Eric S.
Publicado 2018

Content-based microarray search using differential expression profiles

por Engreitz, Jesse M, Morgan, Alexander A, Dudley, Joel T, Chen, Rong, Thathoo, Rahul, Altman, Russ B, Butte, Atul J
Publicado 2010

SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease

por Dey, Kushal K., Gazal, Steven, van de Geijn, Bryce, Kim, Samuel Sungil, Nasser, Joseph, Engreitz, Jesse M., Price, Alkes L.
Publicado 2022

Functional disease architectures reveal unique biological role of transposable elements

por Hormozdiari, Farhad, van de Geijn, Bryce, Nasser, Joseph, Weissbrod, Omer, Gazal, Steven, Ju, Chelsea J. -T., Connor, Luke O’, Hujoel, Margaux L. A., Engreitz, Jesse, Hormozdiari, Fereydoun, Price, Alkes L.
Publicado 2019

Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease

por Yu, Mengyao, Tcheandjieu, Catherine, Georges, Adrien, Xiao, Ke, Tejeda, Helio, Dina, Christian, Le Tourneau, Thierry, Fiterau, Madalina, Judy, Renae, Tsao, Noah L., Amgalan, Dulguun, Munger, Chad J., Engreitz, Jesse M., Damrauer, Scott M., Bouatia-Naji, Nabila, Priest, James R.
Publicado 2022

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

por Ray, John P., de Boer, Carl G., Fulco, Charles P., Lareau, Caleb A., Kanai, Masahiro, Ulirsch, Jacob C., Tewhey, Ryan, Ludwig, Leif S., Reilly, Steven K., Bergman, Drew T., Engreitz, Jesse M., Issner, Robbyn, Finucane, Hilary K., Lander, Eric S., Regev, Aviv, Hacohen, Nir
Publicado 2020

Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability

por Boulting, Gabriella L., Durresi, Ershela, Ataman, Bulent, Sherman, Maxwell A., Mei, Kevin, Harmin, David A., Carter, Ava C., Hochbaum, Daniel R., Granger, Adam J., Engreitz, Jesse M, Hrvatin, Sinisa, Blanchard, Michael R., Yang, Marty G., Griffith, Eric C., Greenberg, Michael E.
Publicado 2021

Topological Organization of Multi-chromosomal Regions by Firre

por Hacisuleyman, Ezgi, Goff, Loyal A., Trapnell, Cole, Williams, Adam, Henao-Mejia, Jorge, Sun, Lei, McClanahan, Patrick, Hendrickson, David G., Sauvageau, Martin, Kelley, David R., Morse, Michael, Engreitz, Jesse, Lander, Eric S., Guttman, Mitch, Lodish, Harvey F., Flavell, Richard, Raj, Arjun, Rinn, John L.
Publicado 2014

KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress

por Moonen, Jan-Renier, Chappell, James, Shi, Minyi, Shinohara, Tsutomu, Li, Dan, Mumbach, Maxwell R., Zhang, Fan, Nair, Ramesh V., Nasser, Joseph, Mai, Daniel H., Taylor, Shalina, Wang, Lingli, Metzger, Ross J., Chang, Howard Y., Engreitz, Jesse M., Snyder, Michael P., Rabinovitch, Marlene
Publicado 2022

Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension

por Isobe, Sarasa, Nair, Ramesh V., Kang, Helen Y., Wang, Lingli, Moonen, Jan-Renier, Shinohara, Tsutomu, Cao, Aiqin, Taylor, Shalina, Otsuki, Shoichiro, Marciano, David P., Harper, Rebecca L., Adil, Mir S., Zhang, Chongyang, Lago-Docampo, Mauro, Körbelin, Jakob, Engreitz, Jesse M., Snyder, Michael P., Rabinovitch, Marlene
Publicado 2023

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

por Nandakumar, Satish K, McFarland, Sean K, Mateyka, Laura M, Lareau, Caleb A, Ulirsch, Jacob C, Ludwig, Leif S, Agarwal, Gaurav, Engreitz, Jesse M, Przychodzen, Bartlomiej, McConkey, Marie, Cowley, Glenn S, Doench, John G, Maciejewski, Jaroslaw P, Ebert, Benjamin L, Root, David E, Sankaran, Vijay G
Publicado 2019

Activity-by-Contact model of enhancer-promoter regulation from thousands of CRISPR perturbations

por Fulco, Charles P., Nasser, Joseph, Jones, Thouis R., Munson, Glen, Bergman, Drew T., Subramanian, Vidya, Grossman, Sharon R., Anyoha, Rockwell, Doughty, Benjamin R., Patwardhan, Tejal A., Nguyen, Tung H., Kane, Michael, Perez, Elizabeth M., Durand, Neva C., Lareau, Caleb A., Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric S., Engreitz, Jesse M.
Publicado 2019

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

por Jiao, Yang, Ahmed, Umer, Sim, M.F. Michelle, Bejar, Andrea, Zhang, Xiaolan, Talukder, M. Mesbah Uddin, Rice, Robert, Flannick, Jason, Podgornaia, Anna I., Reilly, Dermot F., Engreitz, Jesse M., Kost-Alimova, Maria, Hartland, Kate, Mercader, Josep-Maria, Georges, Sara, Wagh, Vilas, Tadin-Strapps, Marija, Doench, John G., Edwardson, J. Michael, Rochford, Justin J., Rosen, Evan D., Majithia, Amit R.
Publicado 2019

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

por Zekavat, Seyedeh M., Ruotsalainen, Sanni, Handsaker, Robert E., Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M., Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A., Fu, Mao, Johnson, W. Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S., Cupples, L. Adrienne, Rotter, Jerome I., Rich, Stephen S., Post, Wendy, Mitchell, Braxton D., Correa, Adolfo, Metspalu, Andres, Wilson, James G., Salomaa, Veikko, Kellis, Manolis, Daly, Mark J., Neale, Benjamin M., McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2018

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

por Zekavat, Seyedeh M., Ruotsalainen, Sanni, Handsaker, Robert E., Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M., Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A., Fu, Mao, Johnson, W. Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S., Cupples, L. Adrienne, Rotter, Jerome I., Rich, Stephen S., Post, Wendy, Mitchell, Braxton D., Correa, Adolfo, Metspalu, Andres, Wilson, James G., Salomaa, Veikko, Kellis, Manolis, Daly, Mark J., Neale, Benjamin M., McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2018

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

por Natarajan, Pradeep, Peloso, Gina M., Zekavat, Seyedeh Maryam, Montasser, May, Ganna, Andrea, Chaffin, Mark, Khera, Amit V., Zhou, Wei, Bloom, Jonathan M., Engreitz, Jesse M., Ernst, Jason, O’Connell, Jeffrey R., Ruotsalainen, Sanni E., Alver, Maris, Manichaikul, Ani, Johnson, W. Craig, Perry, James A., Poterba, Timothy, Seed, Cotton, Surakka, Ida L., Esko, Tonu, Ripatti, Samuli, Salomaa, Veikko, Correa, Adolfo, Vasan, Ramachandran S., Kellis, Manolis, Neale, Benjamin M., Lander, Eric S., Abecasis, Goncalo, Mitchell, Braxton, Rich, Stephen S., Wilson, James G., Cupples, L. Adrienne, Rotter, Jerome I., Willer, Cristen J., Kathiresan, Sekar
Publicado 2018

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

por Zekavat, Seyedeh M., Ruotsalainen, Sanni, Handsaker, Robert E., Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M., Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A., Fu, Mao, Johnson, W. Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S., Cupples, L. Adrienne, Rotter, Jerome I., Rich, Stephen S., Post, Wendy, Mitchell, Braxton D., Correa, Adolfo, Metspalu, Andres, Wilson, James G., Salomaa, Veikko, Kellis, Manolis, Daly, Mark J., Neale, Benjamin M., McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2020

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

por Delorey, Toni M., Ziegler, Carly G. K., Heimberg, Graham, Normand, Rachelly, Yang, Yiming, Segerstolpe, Asa, Abbondanza, Domenic, Fleming, Stephen J., Subramanian, Ayshwarya, Montoro, Daniel T., Jagadeesh, Karthik A., Dey, Kushal K., Sen, Pritha, Slyper, Michal, Pita-Juárez, Yered H., Phillips, Devan, Bloom-Ackerman, Zohar, Barkas, Nick, Ganna, Andrea, Gomez, James, Normandin, Erica, Naderi, Pourya, Popov, Yury V., Raju, Siddharth S., Niezen, Sebastian, Tsai, Linus T.-Y., Siddle, Katherine J., Sud, Malika, Tran, Victoria M., Vellarikkal, Shamsudheen K., Amir-Zilberstein, Liat, Atri, Deepak S., Beechem, Joseph, Brook, Olga R., Chen, Jonathan, Divakar, Prajan, Dorceus, Phylicia, Engreitz, Jesse M., Essene, Adam, Fitzgerald, Donna M., Fropf, Robin, Gazal, Steven, Gould, Joshua, Grzyb, John, Harvey, Tyler, Hecht, Jonathan, Hether, Tyler, Jane-Valbuena, Judit, Leney-Greene, Michael, Ma, Hui, McCabe, Cristin, McLoughlin, Daniel E., Miller, Eric M., Muus, Christoph, Niemi, Mari, Padera, Robert, Pan, Liuliu, Pant, Deepti, Pe’er, Carmel, Pfiffner-Borges, Jenna, Pinto, Christopher J., Plaisted, Jacob, Reeves, Jason, Ross, Marty, Rudy, Melissa, Rueckert, Erroll H., Siciliano, Michelle, Sturm, Alexander, Todres, Ellen, Waghray, Avinash, Warren, Sarah, Zhang, Shuting, Zollinger, Daniel R., Cosimi, Lisa, Gupta, Rajat M., Hacohen, Nir, Hide, Winston, Price, Alkes L., Rajagopal, Jayaraj, Tata, Purushothama Rao, Riedel, Stefan, Szabo, Gyongyi, Tickle, Timothy L., Hung, Deborah, Sabeti, Pardis C., Novak, Richard, Rogers, Robert, Ingber, Donald E., Jiang, Z. Gordon, Juric, Dejan, Babadi, Mehrtash, Farhi, Samouil L., Stone, James R., Vlachos, Ioannis S., Solomon, Isaac H., Ashenberg, Orr, Porter, Caroline B.M., Li, Bo, Shalek, Alex K., Villani, Alexandra-Chloé, Rozenblatt-Rosen, Orit, Regev, Aviv
Publicado 2021

Inherited Causes of Clonal Hematopoiesis in 97,691 TOPMed Whole Genomes

por Bick, Alexander G., Weinstock, Joshua S., Nandakumar, Satish K., Fulco, Charles P., Bao, Erik L., Zekavat, Seyedeh M., Szeto, Mindy D., Liao, Xiaotian, Leventhal, Matthew J., Nasser, Joseph, Chang, Kyle, Laurie, Cecelia, Burugula, Bala Bharathi, Gibson, Christopher J., Lin, Amy E., Taub, Margaret A., Aguet, Francois, Ardlie, Kristin, Mitchell, Braxton D., Barnes, Kathleen C., Moscati, Arden, Fornage, Myriam, Redline, Susan, Psaty, Bruce M., Silverman, Edwin K., Weiss, Scott T., Palmer, Nicholette D., Vasan, Ramachandran S., Burchard, Esteban G., Kardia, Sharon L. R., He, Jiang, Kaplan, Robert C., Smith, Nicholas L., Arnett, Donna K., Schwartz, David A., Correa, Adolfo, de Andrade, Mariza, Guo, Xiuqing, Konkle, Barbara A., Custer, Brian, Peralta, Juan M., Gui, Hongsheng, Meyers, Deborah A., McGarvey, Stephen T., Chen, Ida Yii-Der., Shoemaker, M. Benjamin, Peyser, Patricia A., Broome, Jai G., Gogarten, Stephanie M., Wang, Fei Fei, Wong, Quenna, Montasser, May E., Daya, Michelle, Kenny, Eimear E., North, Kari E., Launer, Lenore J., Cade, Brian E., Bis, Joshua C., Cho, Michael H., Lasky-Su, Jessica, Bowden, Donald W., Cupples, L. Adrienne., Mak, Angel C., Becker, Lewis C., Smith, Jennifer A., Kelly, Tanika N., Aslibekyan, Stella, Heckbert, Susan R., Tiwari, Hemant K., Yang, Ivana V., Heit, John A., Lubitz, Steven, Johnsen, Jill M., Curran, Joanne E., Wenzel, Sally E., Weeks, Daniel E., Rao, Dabeeru C., Darbar, Dawood, Moon, Jee-Young, Tracy, Russell P., Buth, Erin J., Rafaels, Nicholas, Loos, Ruth J.F., Durda, Peter, Liu, Yongmei, Hou, Lifang, Lee, Jiwon, Kachroo, Priyadarshini, Freedman, Barry I., Levy, Daniel, Bielak, Lawrence F., Hixson, James E., Floyd, James S., Whitsel, Eric A., Ellinor, Patrick T., Irvin, Marguerite R., Fingerlin, Tasha E., Raffield, Laura M., Armasu, Sebastian M., Wheeler, Marsha M., Sabino, Ester C., Blangero, John, Williams, L. Keoki, Levy, Bruce D., Huey-Herng Sheu, Wayne, Roden, Dan M., Boerwinkle, Eric, Manson, JoAnn E., Mathias, Rasika A., Desai, Pinkal, Taylor, Kent D., Johnson, Andrew D., Auer, Paul L., Kooperberg, Charles, Laurie, Cathy C., Blackwell, Thomas W., Smith, Albert V., Zhao, Hongyu, Lange, Ethan, Lange, Leslie, Rich, Stephen S., Rotter, Jerome I., Wilson, James G., Scheet, Paul, Kitzman, Jacob O., Lander, Eric S., Engreitz, Jesse M., Ebert, Benjamin L., Reiner, Alexander P., Jaiswal, Siddhartha, Abecasis, Gonçalo, Sankaran, Vijay G., Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2020