Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells

por Bongiorno-Borbone, Lucilla, Giacobbe, Arianna, Compagnone, Mirco, Eramo, Adriana, De Maria, Ruggero, Peschiaroli, Angelo, Melino, Gerry
Publicado 2015

Lipid Storage and Autophagy in Melanoma Cancer Cells

por Giampietri, Claudia, Petrungaro, Simonetta, Cordella, Martina, Tabolacci, Claudio, Tomaipitinca, Luana, Facchiano, Antonio, Eramo, Adriana, Filippini, Antonio, Facchiano, Francesco, Ziparo, Elio
Publicado 2017

Targeting Melanoma-Initiating Cells by Caffeine: In Silico and In Vitro Approaches

por Tabolacci, Claudio, Cordella, Martina, Rossi, Stefania, Bonaccio, Marialaura, Eramo, Adriana, Mischiati, Carlo, Beninati, Simone, Iacoviello, Licia, Facchiano, Antonio, Facchiano, Francesco
Publicado 2021

Lung Cancer Organoids: The Rough Path to Personalized Medicine

por Rossi, Rachele, De Angelis, Maria Laura, Xhelili, Eljona, Sette, Giovanni, Eramo, Adriana, De Maria, Ruggero, Cesta Incani, Ursula, Francescangeli, Federica, Zeuner, Ann
Publicado 2022

CRIPTO Is a Marker of Chemotherapy-Induced Stem Cell Expansion in Non-Small Cell Lung Cancer

por Francescangeli, Federica, De Angelis, Maria Laura, Rossi, Rachele, Sette, Giovanni, Eramo, Adriana, Boe, Alessandra, Guardiola, Ombretta, Tang, Tao, Yu, Shi-Cang, Minchiotti, Gabriella, Zeuner, Ann
Publicado 2022

Quantitative Evaluation of CFTR Gene Expression: A Comparison between Relative Quantification by Real-Time PCR and Absolute Quantification by Droplet Digital PCR

por Bruno, Sabina Maria, Blaconà, Giovanna, Lo Cicero, Stefania, Castelli, Germana, Virgulti, Mariarita, Testino, Giancarlo, Pierandrei, Silvia, Fuso, Andrea, Cimino, Giuseppe, Ferraguti, Giampiero, Eramo, Adriana, Lucarelli, Marco
Publicado 2023

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

por Del Bufalo, Donatella, Desideri, Marianna, De Luca, Teresa, Di Martile, Marta, Gabellini, Chiara, Monica, Valentina, Busso, Simone, Eramo, Adriana, De Maria, Ruggero, Milella, Michele, Trisciuoglio, Daniela
Publicado 2014

Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts

por Sette, Giovanni, Fecchi, Katia, Salvati, Valentina, Lotti, Fiorenza, Pilozzi, Emanuela, Duranti, Enrico, Biffoni, Mauro, Pagliuca, Alfredo, Martinetti, Daniela, Memeo, Lorenzo, Milella, Michele, De Maria, Ruggero, Eramo, Adriana
Publicado 2013

EGFR Inhibition Abrogates Leiomyosarcoma Cell Chemoresistance through Inactivation of Survival Pathways and Impairment of CSC Potential

por Sette, Giovanni, Salvati, Valentina, Memeo, Lorenzo, Fecchi, Katia, Colarossi, Cristina, Di Matteo, Paola, Signore, Michele, Biffoni, Mauro, D’Andrea, Vito, De Antoni, Enrico, Canzonieri, Vincenzo, De Maria, Ruggero, Eramo, Adriana
Publicado 2012

Theratyping cystic fibrosis in vitro in ALI culture and organoid models generated from patient-derived nasal epithelial conditionally reprogrammed stem cells

por Sette, Giovanni, Lo Cicero, Stefania, Blaconà, Giovanna, Pierandrei, Silvia, Bruno, Sabina Maria, Salvati, Valentina, Castelli, Germana, Falchi, Mario, Fabrizzi, Benedetta, Cimino, Giuseppe, De Maria, Ruggero, Biffoni, Mauro, Eramo, Adriana, Lucarelli, Marco
Publicado 2021

Ex Vivo Irradiation of Lung Cancer Stem Cells Identifies the Lowest Therapeutic Dose Needed for Tumor Growth Arrest and Mass Reduction In Vivo

por Puglisi, Caterina, Giuffrida, Raffaella, Borzì, Giuseppina, Illari, Salvatore, Caronia, Francesco Paolo, Di Mattia, Paolo, Colarossi, Cristina, Ferini, Gianluca, Martorana, Emanuele, Sette, Giovanni, Eramo, Adriana, Lorico, Aurelio, Di Grazia, Alfio, Forte, Stefano
Publicado 2022

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

por Tafani, Marco, Di Vito, Maura, Frati, Alessandro, Pellegrini, Laura, De Santis, Elena, Sette, Giovanni, Eramo, Adriana, Sale, Patrizio, Mari, Emanuela, Santoro, Antonio, Raco, Antonino, Salvati, Maurizio, De Maria, Ruggero, Russo, Matteo A
Publicado 2011

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

por Di Martile, Marta, Desideri, Marianna, De Luca, Teresa, Gabellini, Chiara, Buglioni, Simonetta, Eramo, Adriana, Sette, Giovanni, Milella, Michele, Rotili, Dante, Mai, Antonello, Carradori, Simone, Secci, Daniela, De Maria, Ruggero, Del Bufalo, Donatella, Trisciuoglio, Daniela
Publicado 2016

L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fibrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro gu...

por Lo Cicero, Stefania, Castelli, Germana, Blaconà, Giovanna, Bruno, Sabina Maria, Sette, Giovanni, Pigliucci, Riccardo, Villella, Valeria Rachela, Esposito, Speranza, Zollo, Immacolata, Spadaro, Francesca, Maria, Ruggero De, Biffoni, Mauro, Cimino, Giuseppe, Amato, Felice, Lucarelli, Marco, Eramo, Adriana
Publicado 2023

Correction to: L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fbrosis patient-derived air–liquid interface (ALI) cultures and organoid...

por Lo Cicero, Stefania, Castelli, Germana, Blaconà, Giovanna, Bruno, Sabina Maria, Sette, Giovanni, Pigliucci, Riccardo, Villella, Valeria Rachela, Esposito, Speranza, Zollo, Immacolata, Spadaro, Francesca, De Maria, Ruggero, Biffoni, Mauro, Cimino, Giuseppe, Amato, Felice, Lucarelli, Marco, Eramo, Adriana
Publicado 2023

A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells

por Orienti, Isabella, Salvati, Valentina, Sette, Giovanni, Zucchetti, Massimo, Bongiorno-Borbone, Lucilla, Peschiaroli, Angelo, Zolla, Lello, Francescangeli, Federica, Ferrari, Mariella, Matteo, Cristina, Bello, Ezia, Di Virgilio, Antonio, Falchi, Mario, De Angelis, Maria Laura, Baiocchi, Marta, Melino, Gerry, De Maria, Ruggero, Zeuner, Ann, Eramo, Adriana
Publicado 2019

Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models

por Del Curatolo, Anais, Conciatori, Fabiana, Cesta Incani, Ursula, Bazzichetto, Chiara, Falcone, Italia, Corbo, Vincenzo, D’Agosto, Sabrina, Eramo, Adriana, Sette, Giovanni, Sperduti, Isabella, De Luca, Teresa, Marabese, Mirko, Shirasawa, Senji, De Maria, Ruggero, Scarpa, Aldo, Broggini, Massimo, Del Bufalo, Donatella, Cognetti, Francesco, Milella, Michele, Ciuffreda, Ludovica
Publicado 2018

A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors

por Orienti, Isabella, Francescangeli, Federica, De Angelis, Maria Laura, Fecchi, Katia, Bongiorno-Borbone, Lucilla, Signore, Michele, Peschiaroli, Angelo, Boe, Alessandra, Bruselles, Alessandro, Costantino, Angelita, Eramo, Adriana, Salvati, Valentina, Sette, Giovanni, Contavalli, Paola, Zolla, Lello, Oki, Toshihiko, Kitamura, Toshio, Spada, Massimo, Giuliani, Alessandro, Baiocchi, Marta, La Torre, Filippo, Melino, Gerry, Tartaglia, Marco, De Maria, Ruggero, Zeuner, Ann
Publicado 2019

In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells

por Kleinfelder, Karina, Lotti, Virginia, Eramo, Adriana, Amato, Felice, Lo Cicero, Stefania, Castelli, Germana, Spadaro, Francesca, Farinazzo, Alessia, Dell’Orco, Daniele, Preato, Sara, Conti, Jessica, Rodella, Luca, Tomba, Francesco, Cerofolini, Angelo, Baldisseri, Elena, Bertini, Marina, Volpi, Sonia, Villella, Valeria Rachela, Esposito, Speranza, Zollo, Immacolata, Castaldo, Giuseppe, Laudanna, Carlo, Sorsher, Eric J., Hong, Jeong, Joshi, Disha, Cutting, Garry, Lucarelli, Marco, Melotti, Paola, Sorio, Claudio
Publicado 2023

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

por Milella, Michele, Falcone, Italia, Conciatori, Fabiana, Matteoni, Silvia, Sacconi, Andrea, De Luca, Teresa, Bazzichetto, Chiara, Corbo, Vincenzo, Simbolo, Michele, Sperduti, Isabella, Benfante, Antonina, Del Curatolo, Anais, Cesta Incani, Ursula, Malusa, Federico, Eramo, Adriana, Sette, Giovanni, Scarpa, Aldo, Konopleva, Marina, Andreeff, Michael, McCubrey, James Andrew, Blandino, Giovanni, Todaro, Matilde, Stassi, Giorgio, De Maria, Ruggero, Cognetti, Francesco, Del Bufalo, Donatella, Ciuffreda, Ludovica
Publicado 2017