NetWalker: a contextual network analysis tool for functional genomics

por Komurov, Kakajan, Dursun, Serkan, Erdin, Serkan, Ram, Prahlad T
Publicado 2012

Function prediction from networks of local evolutionary similarity in protein structure

por Erdin, Serkan, Venner, Eric, Lisewski, Andreas Martin, Lichtarge, Olivier
Publicado 2013

Accurate Protein Structure Annotation through Competitive Diffusion of Enzymatic Functions over a Network of Local Evolutionary Similarities

por Venner, Eric, Lisewski, Andreas Martin, Erdin, Serkan, Ward, R. Matthew, Amin, Shivas R., Lichtarge, Olivier
Publicado 2010

De-Orphaning the Structural Proteome through Reciprocal Comparison of Evolutionarily Important Structural Features

por Ward, R. Matthew, Erdin, Serkan, Tran, Tuan A., Kristensen, David M., Lisewski, Andreas Martin, Lichtarge, Olivier
Publicado 2008

Evolutionary Trace Annotation Server: automated enzyme function prediction in protein structures using 3D templates

por Matthew Ward, R., Venner, Eric, Daines, Bryce, Murray, Stephen, Erdin, Serkan, Kristensen, David M., Lichtarge, Olivier
Publicado 2009

Accounting for epistatic interactions improves the functional analysis of protein structures

por Wilkins, Angela D., Venner, Eric, Marciano, David C., Erdin, Serkan, Atri, Benu, Lua, Rhonald C., Lichtarge, Olivier
Publicado 2013

mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition

por Beauchamp, Roberta L., Erdin, Serkan, Witt, Luke, Jordan, Justin T., Plotkin, Scott R., Gusella, James F., Ramesh, Vijaya
Publicado 2020

Prediction of enzyme function based on 3D templates of evolutionarily important amino acids

por Kristensen, David M, Ward, R Matthew, Lisewski, Andreas Martin, Erdin, Serkan, Chen, Brian Y, Fofanov, Viacheslav Y, Kimmel, Marek, Kavraki, Lydia E, Lichtarge, Olivier
Publicado 2008

TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling

por Martin, Pauline, Wagh, Vilas, Reis, Surya A., Erdin, Serkan, Beauchamp, Roberta L., Shaikh, Ghalib, Talkowski, Michael, Thiele, Elizabeth, Sheridan, Steven D., Haggarty, Stephen J., Ramesh, Vijaya
Publicado 2020

Physiological Characterization and Transcriptomic Properties of GnRH Neurons Derived From Human Stem Cells

por Keen, Kim L, Petersen, Andrew J, Figueroa, Alexander G, Fordyce, Benjamin I, Shin, Jaeweon, Yadav, Rachita, Erdin, Serkan, Pearce, Robert A, Talkowski, Michael E, Bhattacharyya, Anita, Terasawa, Ei
Publicado 2021

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

por Settembre, Carmine, Zoncu, Roberto, Medina, Diego L, Vetrini, Francesco, Erdin, Serkan, Erdin, SerpilUckac, Huynh, Tuong, Ferron, Mathieu, Karsenty, Gerard, Vellard, Michel C, Facchinetti, Valeria, Sabatini, David M, Ballabio, Andrea
Publicado 2012

Dystonia-specific mutations in THAP1 alter transcription of genes associated with neurodevelopment and myelin

por Domingo, Aloysius, Yadav, Rachita, Shah, Shivangi, Hendriks, William T., Erdin, Serkan, Gao, Dadi, O’Keefe, Kathryn, Currall, Benjamin, Gusella, James F., Sharma, Nutan, Ozelius, Laurie J., Ehrlich, Michelle E., Talkowski, Michael E., Bragg, D. Cristopher
Publicado 2021

Hypomorphic mutation of the mouse Huntington’s disease gene orthologue

por Murthy, Vidya, Tebaldi, Toma, Yoshida, Toshimi, Erdin, Serkan, Calzonetti, Teresa, Vijayvargia, Ravi, Tripathi, Takshashila, Kerschbamer, Emanuela, Seong, Ihn Sik, Quattrone, Alessandro, Talkowski, Michael E., Gusella, James F., Georgopoulos, Katia, MacDonald, Marcy E., Biagioli, Marta
Publicado 2019

Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR

por Tai, Derek J. C., Ragavendran, Ashok, Manavalan, Poornima, Stortchevoi, Alexei, Seabra, Catarina M., Erdin, Serkan, Collins, Ryan L., Blumenthal, Ian, Chen, Xiaoli, Shen, Yiping, Sahin, Mustafa, Zhang, Chengsheng, Lee, Charles, Gusella, James F., Talkowski, Michael E.
Publicado 2016

Pain correlates with germline mutation in schwannomatosis

por Jordan, Justin T., Smith, Miriam J., Walker, James A., Erdin, Serkan, Talkowski, Michael E., Merker, Vanessa L., Ramesh, Vijaya, Cai, Wenli, Harris, Gordon J., Bredella, Miriam A., Seijo, Marlon, Suuberg, Alessandra, Gusella, James F., Plotkin, Scott R.
Publicado 2018

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

por Kovalenko, Marina, Erdin, Serkan, Andrew, Marissa A, St Claire, Jason, Shaughnessey, Melissa, Hubert, Leroy, Neto, João Luís, Stortchevoi, Alexei, Fass, Daniel M, Mouro Pinto, Ricardo, Haggarty, Stephen J, Wilson, John H, Talkowski, Michael E, Wheeler, Vanessa C
Publicado 2020

Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons

por Seabra, Catarina M., Aneichyk, Tatsiana, Erdin, Serkan, Tai, Derek J. C., De Esch, Celine E. F., Razaz, Parisa, An, Yu, Manavalan, Poornima, Ragavendran, Ashok, Stortchevoi, Alexei, Abad, Clemer, Young, Juan I., Maciel, Patricia, Talkowski, Michael E., Gusella, James F.
Publicado 2020

Potential molecular consequences of transgene integration: The R6/2 mouse example

por Jacobsen, Jessie C., Erdin, Serkan, Chiang, Colby, Hanscom, Carrie, Handley, Renee R., Barker, Douglas D., Stortchevoi, Alex, Blumenthal, Ian, Reid, Suzanne J., Snell, Russell G., MacDonald, Marcy E., Morton, A. Jennifer, Ernst, Carl, Gusella, James F., Talkowski, Michael E.
Publicado 2017

CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing

por Kerschbamer, Emanuela, Arnoldi, Michele, Tripathi, Takshashila, Pellegrini, Miguel, Maturi, Samuele, Erdin, Serkan, Salviato, Elisa, Di Leva, Francesca, Sebestyén, Endre, Dassi, Erik, Zarantonello, Giulia, Benelli, Matteo, Campos, Eric, Basson, M Albert, Gusella, James F, Gustincich, Stefano, Piazza, Silvano, Demichelis, Francesca, Talkowski, Michael E, Ferrari, Francesco, Biagioli, Marta
Publicado 2022

Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

por Lim, Elaine T., Chan, Yingleong, Dawes, Pepper, Guo, Xiaoge, Erdin, Serkan, Tai, Derek J. C., Liu, Songlei, Reichert, Julia M., Burns, Mannix J., Chan, Ying Kai, Chiang, Jessica J., Meyer, Katharina, Zhang, Xiaochang, Walsh, Christopher A., Yankner, Bruce A., Raychaudhuri, Soumya, Hirschhorn, Joel N., Gusella, James F., Talkowski, Michael E., Church, George M.
Publicado 2022