Crystal Structure of the Cytosolic C2a-C2b Domains of Synaptotagmin III: Implications for Ca(+2)-Independent Snare Complex Interaction

por Sutton, R. Bryan, Ernst, James A., Brunger, Axel T.
Publicado 1999

Regulation of Epithelial Branching Morphogenesis and Cancer Cell Growth of the Prostate by Wnt Signaling

por Wang, Bu-Er, Wang, Xi-De, Ernst, James A., Polakis, Paul, Gao, Wei-Qiang
Publicado 2008

Molecular mechanism of the synaptotagmin–SNARE interaction in Ca(2+)-triggered vesicle fusion

por Vrljic, Marija, Strop, Pavel, Ernst, James A., Sutton, R. Bryan, Chu, Steven, Brunger, Axel T.
Publicado 2010

Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP)

por Bainbridge, Travis W., Dunshee, Diana Ronai, Kljavin, Noelyn M., Skelton, Nicholas J., Sonoda, Junichiro, Ernst, James A.
Publicado 2017

Translation Levels Control Multi-Spanning Membrane Protein Expression

por Kim, Hok Seon, Ernst, James A., Brown, Cecilia, Bostrom, Jenny, Fuh, Germaine, Lee, Chingwei V., Huang, Arthur, Vandlen, Richard L., Yansura, Daniel G.
Publicado 2012

High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants

por DiCara, Danielle M., Andersen, Nisana, Chan, Ruby, Ernst, James A., Ayalon, Gai, Lazar, Greg A., Agard, Nicholas J., Hilderbrand, Amy, Hötzel, Isidro
Publicado 2018

Tethered-variable C(L) bispecific IgG: an antibody platform for rapid bispecific antibody screening

por Kim, Hok Seon, Dunshee, Diana Ronai, Yee, Angie, Tong, Raymond K, Kim, Ingrid, Farahi, Farzam, Hongo, Jo-Anne, Ernst, James A, Sonoda, Junichiro, Spiess, Christoph
Publicado 2017

Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ

por Meilandt, William J., Maloney, Janice A., Imperio, Jose, Lalehzadeh, Guita, Earr, Tim, Crowell, Susan, Bainbridge, Travis W., Lu, Yanmei, Ernst, James A., Fuji, Reina N., Atwal, Jasvinder K.
Publicado 2019

Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin

por Ultsch, Mark, Li, Bing, Maurer, Till, Mathieu, Mary, Adolfsson, Oskar, Muhs, Andreas, Pfeifer, Andrea, Pihlgren, Maria, Bainbridge, Travis W., Reichelt, Mike, Ernst, James A., Eigenbrot, Charles, Fuh, Germaine, Atwal, Jasvinder K., Watts, Ryan J., Wang, Weiru
Publicado 2016

Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies

por Gong, Yan, Bourhis, Eric, Chiu, Cecilia, Stawicki, Scott, DeAlmeida, Venita I., Liu, Bob Y., Phamluong, Khanhky, Cao, Tim C., Carano, Richard A. D., Ernst, James A., Solloway, Mark, Rubinfeld, Bonnee, Hannoush, Rami N., Wu, Yan, Polakis, Paul, Costa, Mike
Publicado 2010

Evolutionary Divergence in the Catalytic Activity of the CAM-1, ROR1 and ROR2 Kinase Domains

por Bainbridge, Travis W., DeAlmeida, Venita I., Izrael-Tomasevic, Anita, Chalouni, Cécile, Pan, Borlan, Goldsmith, Joshua, Schoen, Alia P., Quiñones, Gabriel A., Kelly, Ryan, Lill, Jennie R., Sandoval, Wendy, Costa, Mike, Polakis, Paul, Arnott, David, Rubinfeld, Bonnee, Ernst, James A.
Publicado 2014

An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans

por Chung, Shan, Nguyen, Van, Lin, Yuwen Linda, Lafrance-Vanasse, Julien, Scales, Suzie J., Lin, Kevin, Deng, Rong, Williams, Kathi, Sperinde, Gizette, Li, Juan Jenny, Zheng, Kai, Sukumaran, Siddharth, Tesar, Devin, Ernst, James A., Fischer, Saloumeh, Lazar, Greg A., Prabhu, Saileta, Song, An
Publicado 2019

Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy

por Chang, Joshua C., Durinck, Steffen, Chen, Mark Z., Martinez-Martin, Nadia, Zhang, Jingli A., Lehoux, Isabelle, Li, Hong, Lin, May, Wu, Jiansheng, Bainbridge, Travis W., Ernst, James A., Ramani, Sree R., Paduchuri, Sairupa, Kates, Lance, Solon, Margaret, Buechler, Matthew B., Castiglioni, Alessandra, Thai, Minh, Breart, Beatrice, Modrusan, Zora, Peterson, Andrew S., Turley, Shannon J., Sonoda, Junichiro
Publicado 2019

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

por Kolumam, Ganesh, Chen, Mark Z., Tong, Raymond, Zavala-Solorio, Jose, Kates, Lance, van Bruggen, Nicholas, Ross, Jed, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A.D., Dunshee, Diana Ronai, Wu, Ai-Luen, Haley, Benjamin, Anderson, Keith, Warming, Søren, Rairdan, Xin Y., Lewin-Koh, Nicholas, Zhang, Yingnan, Gutierrez, Johnny, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Rajan, Sharmila, Bainbridge, Travis W., Vernes, Jean-Michel, Meng, Y. Gloria, Ziai, James, Soriano, Robert H., Brauer, Matthew J., Chen, Yongmei, Stawicki, Scott, Kim, Hok Seon, Comps-Agrar, Laëtitia, Luis, Elizabeth, Spiess, Christoph, Wu, Yan, Ernst, James A., McGuinness, Owen P., Peterson, Andrew S., Sonoda, Junichiro
Publicado 2015